Orthobullets OLD Flashcards
Anti CCP antibodies are detected in what disease?
RA
Protein C Deficiency causes a _ coagulable state
hyper
Most common radiographic finding of RSD about the knee?
patella osteopenia
Rate of fracture of strut allograft
25%
Rituximab is an antibody against what for RA?
CD20
periarticular erosions are seen in _
Gout
Rivoraxaban is a selective _ inhibitor
10A
Heparin is a _ inhibitor
non specific
Warfarin inhibits _
2,7,9,10
Juvenile RA is associated strongly with…
Uveitis
Mechanism of action for Vancomycion
Inhibition of cell wall synthesis
Protamine reverses the effects of what anti coagulant?
heparin
Medical tx for bone pain from fibrous dysplasia
Bisphosphonates
Binds presynaptic calcium channels to prevent release of neurotrans
gabapentin
Zone of polarizing activity controls what part of limb development
medial to lateral
apical ectodermal ridge controls what part of limb development?
proximal to distal
inhibits prostoglandin formation through IL-1B for pain relief
acetaminophen
Alteration in BMP-4 signaling is associated with _
fibrousdysplasia ossificans progressiva (FOP) - Stone man disease
Bending rigidity proportional to?
r^4
Sports hernias caused by activities that rely upon what hip position?
Hip extension and abduction
Most lethal condition associated with absent Radius
Fanconi’s anemia (aplastic anemia)
Tenotomy of Iliopsoas tendon from medial approach can injure what vessel?
Medial femoral circumflex
Excision of the lateral process of talus for non union leads to incompetence of what ligament
lateral talocalcaneal
Ewing’s is associated with what translocation and what fusion protein?
t(11:22), EWS-FL1
Pareosteal osteosarcoma is treated with?
wide excision alone; no chemo/xrt
Single bundle PCL recon should be tightened at what degree of knee flexion
90
What direction are CMC dislocations usually and what ligament is torn?
dorsal; dorsoradial ligament
What classification system correlates with the apex of curve progression in AIS
Turner-Whitehouse
Highest risk of blood born transmission from transfusion
Hep B
MOA non nitrogen Bisphosphonates
Toxic ATP analog
MOA nitrogen containing bisphosphonates
inhibits farnesyl disphosphate synthase
Position to avoid after remplissage
FF, adduction
primary blood supply to flexor tendons within the sheath?
synovial fluid, not veniculae
Fibular Hemimelia is associated with what ankle/hindfoot abnormalities?
ball and socket ankle, tarsal coalition
Driving reaction time returns to normal after THA at _ weeks
4-6
Type of collagen in Annulus fibrosis
1
Type of collagen in nucleus pulposus
2
During open chain knee extension, max tension on ACL is during _
0-30 extension
During open chain knee extension, max tension on PCL is during _
Deep flexion
BKA amputation with fibula strut is called
Ertl
Traditional long posterior flap BKA called
modified Burgess
Osteotomy for closed triradiates and incongruent joint
Chiari
Osteotomy for closed triradiate and congruent joint?
PAO
Dega osteotomy hinges through
open triradiate
Salter osteotomy hinges through
flexible pubis
Max amount of lateral uncoverage for THA cup
30%
A poly wear rate of greater than 0._mm/yr has increased risk of osteolysis
0.1
What Bone stimulating medication is contraindicated in Paget’s?
Teriparatide (Forteo)
Anterior or posterior ICBG has higher complication rate, duration of pain, and gait abnormalities?
Anterior
lead toxicity affects which growth factor?
PTHrP
hitchhikers thumb, cauliflower ears, severe clubfeet
diastrophic dwarfism
Gene and what it encodes for diastrophic dwarfism?
DTD, sulfate transport protein
Partial tears of the biceps insertion occur in what part of the tendon?
radial aspect
Articular cartilage cells are present in what zone of cartilage?
surface zone