Ortho Fractures Flashcards

(86 cards)

1
Q

Osteogenesis

A

Ossification, the process of bone tissue formation

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2
Q

Endochondral Ossification

A

Bone replaces cartilage models, contain physis

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3
Q

Intramembranous Ossification

A

Undifferentiated mesenchymal cells that differentiate into osteoblasts which form bone (skull bones)

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4
Q

Appositional Ossification

A

Osteoblasts deposit new bone on existing bone resulting increased width of bone. Also plays part in proximal bone healing

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5
Q

Osteoprogenator Cell

A

From mesenchymal stem cells that lead to the formation of osteoblasts, cartilage, or fibrous tissue

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6
Q

Osteoblasts

A

Form bone by generating organic non-mineralized matrix, produces alkaline phosphatase

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7
Q

Osteocytes

A

Osteoblasts that have been surrounded by newly formed mtrix and are the living cells of the bone, communicate by canaliculi. Stimulated by calcitonin and inhibited by PTH

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8
Q

Osteoclast

A

Originate from macrophage lineage, have brush border and create Howship’s lacunae. Function to reabsorb bone and inhibited by calcitonin

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9
Q

Resting Zone

A

Small scattered condrocytes that store glycogen and proteoglycan for later bone and matrix formation

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10
Q

Proliferating Zone

A

Chondrocytes stack into lines in direction of bone growth and proliferate and divide. Longitudinal bone growth occurs

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11
Q

Zone of Hypertrophy

A

Chondrocytes enlarge and responsible for 44-59% of long bone growth. Also MOST COMMON AREA of FRACTURE!

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12
Q

Zone of Calcified Cartilage

A

Chondrocytes die and matrix calcifies, calcification begins at longitudinal septa

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13
Q

Apoptosis

A

Process by which cells undergo programmed cell death and plays role in terminally differentiating chondrocytes by preparing the matrix for calcification

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14
Q

Type 1 Collagen

A

Bone

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15
Q

Type 2 Collagen

A

Cartilage

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16
Q

Function of Calcified Cartilage

A

Remnants of cartilage act as scaffold for osteoid ad diaphyseal vessels invade

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17
Q

Mineralization

A

Collagenous matrix is seeded with calcium hydroxyapatite crystals (accretion=crystal growth)

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18
Q

Bone Cells

A

Osteocytes form when osteoblasts get trapped within newly formed lacunae

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19
Q

Physeal Closure

A

At adulthood skeletal maturity is reached and growth plate becomes solid. Decline in width of physis. Under control of ESTROGEN in both sexes that stops replication of chondrocytes

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20
Q

Ossification Center

A

Location in tissue where ossification begins

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21
Q

Bipartite Patella

A

Patella that has two ossification centers (Patella exhibits intramembranous ossification)

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22
Q

Fracture

A

Break in the integrity of a bone cause by a load/force to the bone that results in decrease in functional capability of the bone

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23
Q

Fracture Patterns

A

Determined by the type/direction of the force, physical characteristics of bone, and speed of the force

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24
Q

Location of Bone Fracture

A
  1. Epiphyseal
  2. Metaphyseal
  3. Diaphyseal
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25
Transverse Fracture
Perpendicular to long axi
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Oblique Fracture
Angulated fracture line
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Spiral
multi-planar break
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Comminuted
More than two fragments
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Segmental
Separate segments
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Intra-articular
Enters joint
31
Naming Direction of Fracture
Always name the direction of the distal fragment
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Non-displaced Fracture
Bone still in anatomical alingment
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Displaced
Not in anatomical Alingment
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Angulated
Fracture has an angle between the fragments
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Bayonet
Longitudinal overlap of fragments | Ex: causes short leg in tibia fracture
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Distraction
Gap between fragments
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Type 1 GA Classification
``` Wound size less than 1 cm Low velocity/energy Minimal soft tissue Damage No crush Little contamination ```
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Type 2 GA Classification
``` 1-10cm wound High velocity/energy No extensive soft tissue damage Slight to moderate crush Moderate contamination ```
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Type 3 A GA Classification
``` Wound size greater than 10cm High velocity/energy Extensive soft tissue damage with adequate coverage and no need for flaps No significant vascular injury High contamination ```
40
Type 3 B GA Classification
``` Wound greater than 10cm High velocity/energy Extensive soft tissue damage with periosteal stripping requiring flap covering of bone No vascular injury Massive contamination ```
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Type 3 C GA Classification
Same exact findings as Type B except they do have vascular injury that requires repair for limb salvage
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Plastic Deformation
Pediatric classification where there is bending of bone
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Buckle (torus)
Only one cortex in pediatric bone is involved
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Greenstick
Crack of one cortex and buckle of opposite cortex
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Epiphyseal Plate
Most common type of pediatric fracture, usually in Zone of Hypertrophy
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Apophyseal Plate
Fracture in pediatrics, this area does not add length to bone Ex: tubercles and trochanters
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Pediatric Skeleton
Bone is more porous then adults. Has higher amounts of cartilage, blood supply, osteoblasts compared to adult bone. Joint injuries uncommon because epiphyseal plate fractures more common and fractures can remodel easily
48
Why are fracture around hip in children so severe?
Devastating due to AVN of femoral head which is not easily fixed in child because they are growing and can't receive hip replacement
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Tiplane and Tallaux Fractures
Ankle fracture that are intra-articular and require anatomic reduction. Fracture due to asymmetrical growth of tibia growth plate
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Identifying Child Abuse
Look for fractures in various states of healing
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S-H Type 1
Widening of epiphyseal plate
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S-H Type 2
Fracture through plate and Metaphysis
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S-H Type 3
Fracture through plate and epiphysis
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S-H Type 4
Fracture through both metaphysis and epiphysis
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S-H Type 5
Crushed epiphysis leading to fusion and closure of growth plate at early age
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Stages of Fracture Healing
1) Bleeding- devascularizes and forms hematoma 2) Resorption- osteoclasts and inflammatory response 3) Mesenchymal differentiation into osteo and fibro progenitor cells 4) Callous formation
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Bone Circulation
Bone receives 5-10% of cardiac output 1) Nutrient artery system 2) Metaphyseal-epiphyseal system 3) Periosteal system (outer third of diaphysis)
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Bone Repair Stages
1) Hematoma/ inflammatory response 2) Fracture hematoma maturation 3) Conversion of hypertrophic cartilage into bone 4) Bone remodeling
59
Bone Morphogenic Protein
early post-fracture mesenchymal and osteoprogenitor cells facilitate BMP's which convert undifferentiated perivascular mesenchymal cells to form osteoblasts and bone formation
60
TGF-B
Induces mesenchymal cells to produce Type 2 collagen, regulates cartilage and bone formation in fracture callus
61
Fracture Hematoma Maturation (Soft Callus)
Provides progenitor and growth factors for mesenchymal differentiation and endochondral ossification repair
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Woven Bone (Hard Callus)
Weaker haphazard arrangement of collagen when hypertrophic chondrocytes differentiate and calcify during repair
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Osteoclastic tunneling
Remodeling of cortical bone (cutting cones)
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Clastic Resorption
Remodeling cancellous bone followed by blasts laying down new bone
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Wolff's Law
Bone remodels in response to mechanical stress (ex: edema or hematoma)
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Piezoelectric Charge
Compression side (neg charge) activates blast and tension side (pos charge) activates clasts
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Why immobilize a fracture?
The more a fracture is immobilized and brought into proximity of broken ends, the better facilitated repair is and less callus formed - Primary Cortical Healing
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Delayed Union
Fracture that has not healed in twice the normal healing time
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Nonunion
Fracture that had not healed in three times the normal healing time (6 months)
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Atrophic Nonunion
Bone near the fracture becomes pointed with no apparent healing of fracture
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Hypertrophic nonunion
Bone at fracture site form enormous amounts of bone with no healing
72
Malunion
Fracture that is united with unacceptable angulation, rotation, or shortening
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Fracture Blisters
Occur in response to increased compartmental pressure
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Jone's Fracture
Fracture of 5th metatarsal and rarely heals
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Local Complication of Fractures
Vasculare injury, compartment syndrome, tendon/soft tissue injury
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Thromboembolism Complication
DVT and PE are at increased risk when patient suffers fracture in long bone of extremities or in pelvis. Decreased immobilization and compliance in these patients increases risk of embolism.
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Homan's Sign
Sever pain in dorsiflexion of foot for patients with DVT. Also, edema seen distally to obstruction
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Fat Embolism Syndrome
Microvascular occlusions throughout organs due to embolizing fat. May occur with long bone fractures and bone marrow seeping into blood. usually occurs within 48 hours of break
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Conditions Associated with Fat Embolism
1) Steroid Therapy 2) Sickle Cell 3) Alcoholic fatty liver
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Classic Triad Finding of FE
1) Neurological Abnormalities 2) Hypoxemia 3) Petechial Rash
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Compartment Syndrom
Increased pressure in a compartment due to bleeding, increased cappillary perm, or compression (tight dressing) can lead to compromise of circulation and function of tissue
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Symptoms of Compartment Syndrome
Pain, Palor, Paresthesias, Pulselessness
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RSD
Reflex Sympathetic Dystrophy AKA Complex Regional Pain Syndrome is disruption of autonomic nervous system Type 1: triggered by tissue injury Type 2: Triggered by nerve injury
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Stages of CRPS
Acute, Dystrophic, Atrophic
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Pathological Fractures
Bone break in an area weakend by another disease process, usually during normal activity. Treatment must address underlying disease process
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Stress Fracture
Pathological fracture that is secondary to repeated microtrauma due to repeated stress causing little breaks over and over