Orgo Flashcards
1
Q
What are the SB/WN?
A
DBN, DBU, KOtBu
DBN and DBU favor Zaitsev while KOtBu favor Hoffmann
2
Q
what are SB/SN?
A
OH, OMe, EtO
3
Q
what are WB/SN?
A
I, Br, Cl, R-S, HS, H2S, R-SH, CN
4
Q
what are WB/WN?
A
H2O, MeOH, EtOH
5
Q
What is Zaitsev?
A
Most substituted alkene
6
Q
What is Hofmann?
A
less substituted alkene
- preferred when base is large (KOtBu)
7
Q
what are the non polar solvent?
A
hexane
toulene
8
Q
what are the polar protic solvents (H connected to electronegative atom)?
A
H2O, MeOH, Acetic Acid
9
Q
what are polar aprotic solvents?
A
Dimethyl Sulfide, Acetone, Dimethylformamide (DMF), Acetonitrile
10
Q
what are the strong nucleophiles?
A
I, Br, Cl, SH, R-S, OH, R-O, and CN
11
Q
what are the weak nucleophiles?
A
H2O, R-OH
