ORGANOTROPIC AGENTS - Drugs used in gastrointestinal diseases

Question 1

Tick the main approach of peptic ulcer treatment

Answer 1

• Neutralization of gastric acid
• Eradication of Helicobacter pylori
• Inhibition of gastric acid secretion

Question 2

Gastric acid secretion is under the control of

Answer 2

• Histamine
• Acetylcholine
• Gastrin

Question 3

Gastric acid secretion is not under the control of

Answer 3

Serotonin

Question 4

Indicate the drug belonging to proton pump inhibitors

Answer 4

Omeprazole

Question 5

The following agents intensify the secretion of gastric glands

Answer 5

• Gastrin
• Histamine
• Carbonate mineral waters

Question 6

The following agent do not intensify the secretion of gastric glands

Answer 6

Pepsin

Question 7

Which drugs is an agent of substitution therapy?

Answer 7

Hydrochloric acid

Question 8

Choose the drug which is a H2-receptor antagonist

Answer 8

Ranitidine

Question 9

The following drugs are proton pump inhibitors

Answer 9

• Pantoprozole
• Omeprazole
• Rabeprazole

Question 10

Indicate the drug belonging to M1-cholinoblockers

Answer 10

Pirenzepin

Question 11

Which drugs may cause reversible gynecomastia?

Answer 11

Cimetidine

Question 12

True or False. Cimetidine has no effect on hepatic drug metabolism.

Answer 12

FALSE

Question 13

Tick the drug forming a physical barrier to HCL and Pepsin

Answer 13

Sucralfate

Question 14

Which drug is an analog of prostaglandin E1?

Answer 14

Misoprostole

Question 15

Select the drug stimulating the protective function of the mucous barrier and the stability of the mucous membrane against damaging factors

Answer 15

Misoprostol

Question 16

True or False. Antacids are weak bases that react with gastric hydrochloric acid to form salt and water.

Answer 16

TRUE

Question 17

Antacids drugs

Answer 17

• Maalox
• Mylanta
• Almagel

Question 18

Are not Antacids drugs

Answer 18

Misoprostol

Question 19

Indicate the drug that cause metabolic alkalosis

Answer 19

Sodium bicarbonate

Question 20

Drug that causes constipation

Answer 20

Aluminium hydroxide

Question 21

The following drugs stimulate appetite

Answer 21

• Vitamins
• Bitters
• Insulin

Question 22

The following drugs do not stimulate appetite

Answer 22

Fepranone

Question 23

True or False. Ethyl alcohol is an agent decreasing appetite.

Answer 23

FALSE

Question 24

Fenfluramine

Answer 24

An anorexigenic agent affecting serotoninergic system

Question 25

The following drugs intensify gastrointestinal motility

Answer 25

- Metoclopramide - Domperidone - Cisapride

Question 26

The following drugs do not intensify gastrointestinal motility

Answer 26

Papaverine

Question 27

True or False. Metoclopramide is a potent dopamine antagonist.

Answer 27

TRUE

Question 28

Emetic drug of central action

Answer 28

Apomorphine hydrochloride

Question 29

The mechanism of Metoclopramide antiemetic action

Answer 29

D2-dopamine and 5-HT3-serotonin receptor blocking effect

Question 30

The emetic agent having a reflex action

Answer 30

Ipecacuanha derivatives

Question 31

The following drugs are antiemetics

Answer 31

- Metoclopramide - Ondansetron - Chlorpromazine

Question 32

The following drugs are not antiemetics

Answer 32

Apomorphine hydrochloride

Question 33

Indicate an antiemetic agent which is related to neuroleptics

Answer 33

Prochlorperazine

Question 34

Drugs that reduces intestinal peristalsis

Answer 34

- Loperamide - Methyl cellulose - Magnesium aluminium silicate

Question 35

Drugs that does not reduces intestinal peristalsis

Answer 35

Cisapride

Question 36

Indicate the laxative drug belonging to osmotic laxatives

Answer 36

Sodium phosphate

Question 37

The mechanism of stimulant purgatives is

Answer 37

Increasing motility and secretion

Question 38

Drug irritating the gut and causing increased peristalsis

Answer 38

Phenolphthalein

Question 39

The following drugs stimulate bile production and bile secretion

Answer 39

- Cholenszyme - Oxaphenamide - Cholosas

Question 40

The following drugs do not stimulate bile production and bile secretion

Answer 40

Chenodiol

Question 41

Stimulant of bile production of vegetable origin

Answer 41

Cholosas

Question 42

Select the drug which inhibits peristalsis

Answer 42

Loperamide

Question 43

The drug affecting the biliary system and relaxing Oddy sphincter

Answer 43

No-spa