Organogenesis Flashcards

1
Q

What is embryonic folding ?

A

Folding of the flat trilaminar germ layer into a cylindrical embryo

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2
Q

In which planes does Embryonic folding occurs?

A

Median and horizontal planes

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3
Q

During median folding, at the beginning of the 4th-week cranial neural folding occurs to form what?

A

Primordium of the brain

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4
Q

Describe development of the brain

A

Initially the brain projects dorsally into the amniotic cavity, later the developing forehead grows cranially beyond the oropharyngeal membrane overhanging the developing heart.

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5
Q

During cranial neural folding, the movement of structures to the ventral surface happens at the same time and in different directions, namely:

A

Septum transversum
Primordial heart
pericardial coelom
oropharyngeal

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6
Q

The foregut is developed from which part of the embryo?

A

An umbilical vesicle endoderm incorparated into the embryo

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7
Q

The foregut lies intermediate of:

A

The Forebrain and the primordial heart

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8
Q

Which membrane separate the foregut from the stomodeum?

A

The Oropharyngeal membrane

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9
Q

lies caudal to the heart and develops into central tendon of the diaphragm after folding…….

A

Septum transversum

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10
Q

Describe the position of the pericardial coelom after folding

A

lies ventral to the heart
lies cranial to the septum transversum

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11
Q

Describe the caudal folding of the embryo

A

caudal eminences projects over cloacal membrane, the endodermal layer incorporates into the embryo as Hindgut- the future transverse, descending and he rectum

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12
Q

After folding the primitive streak will lie caudal to ?

A

The Cloacal membrane

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13
Q

Allantois projects into the umbilical cord from which structure?

A

the umbilical vesicle/ yolk sac

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14
Q

Describe the folding of the primordia of ventrolateral abdominal wall

A

folds towards the median plane median plane, rolls embryonic disc edges ventrally

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15
Q

The midgut is formed ……

A

when the abdominal cavity formation incorporates the endodermal layer

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16
Q

Reduction of the connection of the midgut to the umbilical vesicle result in the formation of?

A

Omphaloenteric/ vitelline duct

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17
Q

Ectoderm gives rise to which structures?

A

the central and peripheral nervous system
sensory epithelia of the eyes, ears and nose
neural crest cells forms spinal cord and cranial nerve cells

18
Q

Mesoderm give rise which structures of the embryo?

A

Connective tissue
cartilage
heart
pleura

19
Q

Endoderm give rise to?

A

Epithelial lining of digestive and respiratory
thyroid and parathyroid glands
Epithelial linning of urinary bladder

20
Q

how many somites does an embryo have in the 4th week

A

4-12 somites dorsally

20
Q

Neural tube is formed opposite——–widely open at ———-and ———-.

A

The somites
caudal
rostral neuropores

21
Q

The first pharyngeal arches are visible by 24 days. which parts contributes to the mandible and the maxilla

A

the major parts contributes to the mandible
Rostral extension contributes to the maxilla

22
Q

in which days are the upper limbs recognizable

A

26/27 days as small swellings on the ventrolateral body walls

23
Q

Lens Placodes develops into?

A

future lenses of the eyes

24
Q

the third pharyngeal arch pairs are visible at….

A

at 26 days

25
Q

the 4th pharyngeal arches are visible at?

A

The end of the 4th week

26
Q

At the end of the 4th week 3 structures are visible namely…?

A

the fourth of Pharyngeal arches
lower limbs buds
caudal eminences
rudiments of the cardiovascular system

27
Q

what minor changes occurs at the fifth week

A

head grows, exceeding other regions. rapid development of brain and facial prominences.

the face soon contacts the heart.

the 2 pharyngeal arch outgrows the 3 and 4th- forming the lateral depression called cervical sinus.

28
Q

ON the 6th week the shows which movements

A

he spontaneous movement of the trunk and developing limbs
also exhibit responses to touch

29
Q

Describe the regional differentiation of the upper limbs

A

development of elbows and hand plates
digital rays begin to develop in hand plates

30
Q

development of lower limb occurs?

A

4-5 days after upper limbs

31
Q

what develops around pharyngeal groove

A

the Auricular hillocks as samll swellings

32
Q

which structure does auricular hillocks form

A

pinna (auricle)

33
Q

external acoustic meatus is formed by

A

pharyngeal groove

34
Q

where does the intestine enter

A

extraembryonic coelom the proximal part of the umbilical cord called umbilical herniation

35
Q

in which week does the the notches appear between digital rays and what are they indicating

A

seventh week
they are indicating hand and foot digital

36
Q

when does upper ossification start

A

by the end of this week 7

37
Q

around week 8

A

hand digit are clearly visible .
notsches on feets are clealy

38
Q

what forms a band

A

scalp vascular plexus

39
Q

why limbs are differentiated

A

purposeful li movements

40
Q

during 8th week

A

Primary ossification of the femur begins
Caudal eminence disappears completely
Hands and feet move towards each other ventrally
Distinct human characteristics present by end of week
- Head still disproportionately large
Eyelids established and fused by end of the week
- United by epithelial fusion
Intestines remain in the umbilical cord proximally
External genitalia is visible, but not distinctive enough

41
Q

coadal eminences appear as ?

A

as Stub