Organic Chem

Question 1

A carboxylic acid is comprised of a carbonyl and what other functional group?

Answer 1

OH

Question 2

An ester is comprised of a carbonyl and what other functional group?

Answer 2

OR

Question 3

An amide is comprised of a carbonyl and what other functional group?

Answer 3

NR2

Question 4

An acyl halide is comprised of a carbonyl and what other functional group?

Answer 4

X (halogen)

Question 5

All carboxylic acid derivatives act as electrophiles. What are the carboxylic acid derivatives? (Hint: EAA)

Answer 5

Ester; Amide; Acyl Halide

Question 6

IUPAC Rules state that what functional group is the highest priority?

Answer 6

The most oxidized functional group (i.e. an Ester R-COOR’)

Question 7

Amides

Answer 7

-RCONR2
amide
made with ammonia + anhydride-

Question 8

Ester

Answer 8

• lacks h bonding and thus has lower b.p
• triacylglycerol
• oate
• formed by alcohol + anhydride

Question 9

Anhydride

Answer 9

formed by two carboxylic acids
RC(O)OC(O)R
higher bp due to greater weight

Question 10

Reactivity of Carboxylic Acid Derivatives

Answer 10

1) Anhydrides are resonance stabilized and have 3 EWG
2) Esters lack 1 EWG oxygen and are thus less reactive
3) Amides have an EDG amino group

Question 11

High Hydrolysis in B Lactams occurs due to __

Answer 11

higher strain and the forcing of the trigonal pyramidal bond geometry on the N atom in the ring reduces resonance , hydrolysis move likely

Question 12

In transesterification the alcohols act as __ and the carbonyl carbon serves as __

Answer 12

nucleophile ; electrophile

Question 13

Esterification cannot occur in water because __

Answer 13

it would revert back to the carboxylic acid

Question 14

Carboxylic acid derivatives are formed via __ reactions which have a loss of water to make 2 molecules –> 1 molecule.

Answer 14

condensation