organic 3 Flashcards
how can we form a-b unsaturated carbonyl compounds + what are they
base attacks acidic alpha hydrogen
move e- to O
use O- and double bond to attack other carbonyls carbon
move e- onto O
O- attacks a H
then reflux to get it!!!
when theres a double bond between the alpha and beta carbon of a carbonyl compound
describe an alpha, beta unsaturated carbonyl compound
carbonyl compound,, with a double bond between the alpha and beta carbon
made from refluxing a carbonyl with an OH on the beta carbon (formed by 2 carbonyls attacking eachother)
how does a ketone react in an acidic environments with other ketones
ketone O is protonated with acid
alpha H is removed and O is neutralised to give a OH.
double bond is formed when H is removed.
O: and double bond attack the C of another ketone carbonyl carbon (after it’s protonated at the O)
e- neutralise O and a bond is formed between the ketones, OH is formed from the new carbonyl. (the one u attacked)
OH attacks a H ,, forms a better LG
water is removed.
how do we form a ring // connect things
we remove an alpha H,, form a double bond and a O-
use this to attack a C that’s partially positive of a carbonyl ( make sure the rings have about 6/5 Cs in them)
think about what H to attack by looking at how many carbons will be in the ring if u attack different ones.
when u form an enolate,, which carbon do u start counting from,,
ngl u need to ask but i feel like look to see if the carbon won’t be pentavalent.
so like normally do the C that’s not bonded to the O
when ur making a bond between 2 carbonyl molecules but have a group between them,, where does the group go
it goes under,, so like where the double bond is is where u cut off the bond making bond. u don’t carry it through a bond and start wherever. u out the other things below it and just bond both carbonyls.
any methyl groups go underrrrr
is the aldehyde H acidic and can it be removed
don’t remove it girl. it’s not acidic it’s stable
can enols always be made
nopeee
if there’s no alpha protons then enols cannot be made.
aka benzaldehyde.
if only 1 reactant can form an enolate what do u do
either react the enolate to its original molecule.
or react the enolate to the molecule that can’t form an enolate
when u are drawing ur 2 carbonyls that reacted how should u change up the molecule
the one ur attacking,, draw it with the H towards the enolate,, if there’s no H’s remember to draw the group underrrr the main chain
when u have an OH what can u do
deprotonate an alpha H
and remove the OH
forming a double bondddd
what do u need to look out for
forming the bonds,, how many C’s u have and how many bonds ur drawing
tertiary amine can attack how many times
once
it forms a quaternary which is its max.
can react with Me-I
is a quaternary amine a good lg
yessss
a quaternary amine is a good lg
when u see a double bond thinkkk
a alpha proton was removed in order to remove a LG
which formed a double bond
