Organic 19: Carboxylic Acid Derivatives: Nucleophilic Acyl Sub

Question 0

Nucleophilic Acyl substitution

Answer 0

Nucleophilic substitution at the carbon atom of an Acyl group

Question 1

Carboxylic acid derivatives

Answer 1

Related group of compounds, all with an Acyl group bonded to an electronegative element & Nucleophilic Acyl substitution as their characteristic reaction type

Question 2

Tetrahedral intermediate

Answer 2

The key intermediate in Nucleophilic Acyl substitution; formed by Nucleophilic addition to the carbonyl group of a Carboxylic acid derivative

Question 3

Fats & oils

Answer 3

Naturally occurring mixtures of glycerol trimesters

Question 4

Fatty acids

Answer 4

Long-chain Carboxylic acids obtained from fats & oils by hydrolysis

Question 5

Saponification

Answer 5

Ester hydrolysis in base; “soap making”

Question 6

Imides

Answer 6

Amides in which 2 carbonyl groups are bonded to the same nitrogen

Question 7

Lac tams

Answer 7

Cyclic amides; analogous to lactones (cyclic esters)

Question 8

Beta-lactam

Answer 8

Penicillin is an example; amide function as part of a 4-membered ring