Oral pathology and oral manifestations of systemic disease Flashcards
What cancer comprised 90% of oral cancers?
Squamous cell carcinoma
How might a squamous cell carcinoma look in the mouth?
White, red, speckled, ulcer, lump
Where are the high risk sites in the oral cavity for squamous cell carcinoma?
Floor of mouth
Lateral border of and ventral tongue
Soft palate
Retromolar pad/ tonsillar pillars
How do well differentiated squamous cell carcinomas appear histopathologically?
Well-differentiated tumour cells very obviously squamous with ‘prickles’ and keratinization
What are some of the differential diagnoses of an oral ulcer?
Recurrent aphthous stomatitis (RAS) (common ulcer)
Trauma
Tumour
Infection
What questions must be asked of a patient with an oral ulcer?
How long has it been there?
Is it the only one there?
Are there any other associated signs and symptoms?
What are some of the differential diagnoses of a lump in the oral cavity?
Hyperplasia
Tumour
Infection/abscess
What are some of the differential diagnoses of a white patch in the oral cavity?
Trauma
Infection
Immune
Dysplasia
What are some of the differential diagnoses of a red patch in the oral cavity?
Vascular
Immune
Dysplasia
What are some of the differential diagnoses of pigmented legions in the oral cavity?
Amalgam tattoo
Drugs
Melanoma
What are some of the differential diagnoses of a dry mouth?
Lack of saliva - dehydration, infection
Salivary gland disease - Sjogrens syndrome, radiotherapy
Diabetes
Diuretics
What are some oral manifestations of iron deficiency?
Recurrent oral ulceration
Oral candida
Angular cheilitis
Smooth tongue
How might bleeding disorders e.g. leukaemia present in the oral cavity?
Spontaneous oral mucosal bleeding usually around the teeth and gums
In which two ways might Crohn’s disease involve the oral cavity?
Directly
Via deficiencies
What are some of the oral manifestations of direct involvement of Crohn’s disease?
Oral ulceration
Mucosal tags
Cobblestone mucosa
Angular cheilitis
