Oral Pathology Flashcards
ABCDE criteria of Melanoma
What type of melanoma does this criterion apply to
Asymmetry Borders are irregular Color variation Diameter is greater than or equal to 6mm Evolution
Superficial spreading melanoma
The facial paralysis scale is also known as the …
House Brackmann Scale
The House Brackmann Scale observes facial paralysis deformities in which three regions of the face
Eye closure, Forehead, and Angle of Mouth
The House Brackmann Scale has how many categories and what does each indicate?
VI
1 - Normal function
2 - Mild deficit with slight weakness
3 - Moderate deformity - eyes can close with max effort
4 - Symmetric at rest - Moderately severe with incomplete eye closure
5 - Asymmetric at rest - Severe dysfunction
6 - Total paralysis
Histology of a nasopalatine duct cyst
Pseudostratified columnar epithelium
Which vessels and nerves are sacrificed when enucleating a nasopalatine duct cyst?
The nasopalatine vessels and nerves
Typical diameter of a nasopalatine duct cyst
10mm - 25mm.
If there is a well-defined radiolucency in the midline of the anterior palate that is >6mm, a nasopalatine duct cyst should be suspected.
Initial pharmacological management of trigeminal neuralgia
Carbamazepine (tegretol).
The dose should be slowly increased until the pain disappears or the patient experiences side effects.
After 6-8 weeks of pain control, the dosage should be titrated
Need to obtain Hepatic Panel and CBC as tegretol is metabolized by the ctyo P450 enzyme in the liver
MOA: Na+ channel blocked/anticonvulsant
How many units of botox are injected into tigeminal neuralgia trigger zones?
50units of botox are injected into TN trigger zones
What is the initial dose of carbamazepine that should be started for TN?
200mg BID.
Obtain CBC and hepatic panel when using carbazempine
Most common vessel that causes classic (idiopathic) TN
Anterior inferior cerebellar or superior cerebellar artery is the most common vessel that is compressed and causes TN.
To establish a diagnosis of MRONJ, what are the three criteria needed?
At least 8 weeks of exposed jaw bone; no history of radiation therapy to the jaws; prior or current history of bisphosphonate therapy
Name the three radiographic presentations of the dentigerous cyst.
- Circumferential
- Central - crown in lumen
- Lateral - portion of crown and portion of root surrounded
Any pericoronal radiolucency that is larger than __mm is considered suggestive of cyst formation and should be submitted for path
4-5mm
What is the histology of a dentigerous cyst?
Atrophic stratified squamous epithelium without significant inflammation
What are the two variants of the OKC?
The syndromic variant associated with nevoid nasal cell carcinoma syndrome and the sporadic variant
What is the histology of an OKC
A uniform layer of stratified squamous epithelium that is 6-8 cells in thickness.
Described as parakeratotic that is corrugated.
Prominent palisading basal layer
Fluid accumulation between this layer and the crown will lead to a dentigerous cyst
Reduced enamel organ epithelium - covers the enamel surface until tooth eruption
Origin of ameloblastoma
Rest of serres
Reverse polarity of nuclei is pathognomonic for what odontogenic tumor
Ameloblastoma
A peripheral ameloblastoma is most likely to be where in the mouth?
The anterior maxilla
Ameloblastoma subtype mostly found in posterior mandible
Desmoplastic
Treatment for solid or multicystic ameloblastoma
Resection with 1cm margin
Treatment for peripheral ameloblastoma
Excision - no recurrence - 6th decade
3 subtypes of unicystic ameloblastomas
Which requires 1cm margin resection
Luminal, intraluminal, mural
Mural requires 1cm of resection
3rd decade of life - no recurrence
The 2/3 tumor
Adenomatoid odontogenic tumor
2/3 canine: 2/3 female: 2nd/3rd decade of life
Tumor with pear shaped radiolucency that expands asymptotically
Adenomatoid odontogenic tumor
Origin of odontogenic myxoma
The dental papilla (a mesenchymal tumor)
Treatment of odontogenic myxoma
Resection with 1 cm margin
Ameloblastic fibroma age range and type of odontogenic tumor
1st and 2nd decades: mixed
Histology: suprabasilar epithelium shows stellate reticulum with ghost cell formation
This is the only cyst associated with a radio-opacity
Calcifying cystic odontogenic tumor (Gorlin Cyst)
Primary affects of glycerol on nerves when used for glycerol this irony
Neurolytic, hyperosmolar, May down regulate central hyper excitability
Ehlers-Danlos Syndrome is caused by a defect in what
a. keratin
b. collagen
c. elastin
d. laminin
Collagen
Most appropriate management for an adenomatoid odontogenic tumor
a. En-bloc resection
b. Decompression followed by enucleation
c. Enucleation and curettage
Enucleation and curettage
