Oral Path Flashcards
Cavernous Sinus Thrombosis
- subcutaneous abscess of the upper lip or intrabony abscess of the anterior mx tooth
- valveless facial veins
Systemic Lupus Erythematosus
- autoimmmune disease
- young adult females
- butterfly rash on face
- heart - endocarditis
- kidney - glomerulonephritis
Ludwig’s angina
- submandibular space infection
- can cause blockage of breathing.
- can kill you b/c the infection goes down retropharyngeal space.
Scarlet Fever
- white coating of tongue that sloughs off and leaves deep red surface with swollen hyperplastic fungiform papillae
Fordyce Granules
- ectopic sebaceous glands
- yellow papules
- bilateral
- lips and buccal mucosa
- 80-90% of caucasians in America have them.
Turner Tooth
- Something causes this succadenous tooth to come out malformed.
- It may be b/c of carious primary tooth or infected.
- Mandibular PM is the most common involved tooth b/c mandibular primary 1 M tooth has most common caries.
Recurrent Aphthous Stomatitis
- found on moveable mucosa
- recurrent with NOT VESICLE PRECEDING
- associated with Human Lymphocyte Antigens (HLA) types
- Tx corticosteroids
- Three types: herpetiform (many small), minor and major (>1cm)
Intrinsic Tooth Stain
- down in dentinal tubules.
- Can only do crowns or veneers to cover these up.
- Common analogue of tetracycline that can cause this kind of staining
- MINOCYCLINE taken for acne.
Benign Mucous Membrane Pemphigoid
- Autoimmune
- Antibodies react to basement membrane zone
- middle age women
- Skin, eyes, and oral
- SUBEPITHELIAL SPLIT
- Corticosteroid PILLS
Condyloma Acuminatum
- HPV of the mouth
- Genital wart can go systemically and can show up in mouth up under upper lip or ventral tongue.
Candidiasis pseudomembranous
- Opportunistic infection: deficient immune system, antibiotic usage or corticosteroid usage
- diagnosed by cytology smear
- White, wipeable patch with red underling base
- palate or buccal mucosa
- found very young (Thrush) or very old
Median Rhomboid Glossitis
- Red atrophy of filiform papillae
- Midline of tongue
- nystatin or clotrimazole
Denture Sore Mouth
- Pt does not remove or clean denture
- hyperplastic CT like
- Rinse mouth and soak denture in antifungal
Recurrent Herpes Simplex
- Reactivation from trigeminal ganglion
- skin or vermilion
Vesicles preceeds ulcers - HSV type 1
- Hard palate and gingival if intraoral - overlays bone
Traumatic Neuroma
- wandering transected nerve with scar tissue
- painful or tender, firm “lump”
- occurs at sites of chronic trauma
Pyogenic Granuloma
- occurs at any age, pregnancy
- Just granulomatous tissue
- Could be from trauma.
- bleeds readily, exophytic (grows outwards), non-painful, grows quickly
- No nerves in there
- Interdental papillae are most common site b/c things get stuck there, overhangs, etc.
Peripheral Giant Cell Granuloma
- often “Liver colored” (brownish purple)
- histology - multinucleated giant cells
- limited to alveolar ridge/gingiva
- usually anterior to first molar region
Central Giant Cell Granuloma
- intrabony
- may cross midline
- histology - multinucleated giant cells
- SAME HISTOLOGY AS: Brown tumor of hyperpapathyoidism and Peripheral Giant Cell Granuloma
- classically a multi-locular RL
Squamous Papilloma
- benign proliferating lesion induced by HPV
- white to pink
- rough surface (cauliflower)
- elevated lesion
Fibroma
- most common CT tumor
- Reactive not true tumor
- Firm, smooth, pink elevated papule/nodule
Granular Cell Tumor
- Dorsum of tongue #1 site
- nodule with smooth or papillated surface
- granular cells - cytoplasm
- psuedoepitheliomatous hyperplasia - aka looks like cancer
- LYSOSOMES
Leukoplakia
- white patch that does not wipe off
- cytology smear doesnt help determine
- incisional biopsy
- tongue and FOM more dangerous sites
Erythroplakia
- red plaque that does not wipe off
- likely to have severe dysplasia and become malignant
- incisional biopsy
Squamous cell carcinoma
- Most common malignancy in oral cavity
- Lower lip can be preceded by actinic cheilitis
- REDor WHITE, firm, irregular, indurated ulcer, painless
- submental node most common lymph node
- mid-lateral border of tongue and FOM
- staging (spread), grade (differentiation)
- alveolar ridge appears poorly defined lucencies without reactive sclerotic border
- p53 tumor gene
Metastatic Disease of the Jaw
- most common site - posterior mandible
- does not cause a shift in occlusion
- usually a poorly defined lucency without sclerotic border
- prostate cancer most common
Monomorphic adenoma
- Canalicular adenoma another name
- upper lip most common
- old adult females
- Firm and asymptomatic
- maybe multinodular
- rare on the lower lip.
- NEVER answer MUCOCELE for upper lip bump.
Leukoedema
- intracellular edema of cells
- AA most common
- bilateral on buccal mucosa most common
- pull on buccall mucosa -> disappears or dissipates
Leukemia
- red, swollen, boggy, bleeding gingiva with ulcers
- get lab tests: CBC, WBC; see decrease in neutrophils and platalets
- Red macules on skin
- Tired feeling (malaise)
- anemia (decrease RBCs)
Verrucous Carcinoma
- large, elevated, papillary
- often associated with smokeless tobacco habit
buccal vestibule most common site - No tendency to metastasize
Pleomorphic adenoma
- benign neoplastic proliferation of parenchymatous glandular cells
- most common tumor of salivary gland origin
- palate most common site, next is parotid
- slow growing, painless mass firm nodular mass, mobile
Adenoid cystic carcinoma
- tumor of the salivary gland
- painless, slow growing masses of the mouth or face
- perineural invasion
- parotid - facial nerve involvement but no upper lip paresthesia
Lateral periodontal Cyst
- true cyst (epithelial lining)
- well circumscribed radioluceny between roots, erupted and vital teeth
- most common seen at mandibular premolars
ameloblastic fibroma
- more common in the first and second decades of life
- most often in posterior mandible
- In 50% of cases an unerupted tooth is involved
- slight to no pain, swelling; not aggressive
- unilocular lesions, occasionally multilocular when larger, with smooth well-demarcated borders.
- Surgical excision with affected tooth
Adenomatoid odontogenic tumor
- child or teenager - more common in females
- more often located in anterior maxilla #1 and anterior mandible #2
- Lucent and calcifications that show speckles of RO.
- associated with unerupted tooth
- YOUNG PERSON- unerupted tooth, don’t say it’s DENTIGEROUS CYST even if though it’s around the impacted crown!!!
- simple enucleation treatment
ameloblastoma
- average age 34
- most common in the posterior mandible
- most common true odontogenic tumor
- multilocular radiolucency “soap bubble”
- superimposed over impacted tooth
- histology - reverse polarization of the nuclei, columnar cells of the periphery
odontoma
- under 20 yrs of age
- radiopacity with radiolucent rim
- compound - anterior identifiable toothlets
- complex - posterior unidentifiable mass
Amelogenesis imperfecta
- teeth lack enamel
- dentin and cementum unaffected
- shaped of root and crown normal
- pulp chambers and RC normal
Cherubism
- autosomal dominate
- young person
- loss of bone in the mandible replaced with fibrous tissue
- multilocular bilateral lucencies
- premature loss of the primary teeth and uneruption of the permanent teeth.
- Normal bone remodeling activity may resume after puberty
Condensing Osteitis
- associated with pulpitis
- nonvital tooth
- periapical opacity
- not connected with root
Dentinogenesis imperfecta
- opalescent dentin - blue/gray
- often associated with OSTEOGENESIS IMPERFECTA
- -blue sclera
- multiple bone fractures
- lack of pulp chambers and root canals
- bell-shaped crown with constricted cervical region
Fibrous Dysplasia
- unilateral mandibular or maxillary expansion
- onset before puberty
- painless swelling, stops at age 20
- ground glass appearance on Radiograph
- cosmetic bone shaving
idiopathic osteosclerosis
- no apparent reason including no pulpitis in adjacent tooth
- no expansion, pain
- radiopacity without peripheral lucent rim
- not connected to tooth’s root
- no treatment necessary
Traumatic Bone Cyst
- spontaneous healing without treatment
- pseudocyst
- radiolucent with scalloped margins
Langerhans Cell Disease
- also called Histiocytosis X
- composed of Langerhans cells
- eosinophilic granuloma
- tooth “floating in air or space”
- Advanced periodontal mimicker!!!
- younger people
Central Neural Lesion
- neurofibroma and Schwannoma
- enlargement of canals and foramina
Paget’s Disease
- older age
- bilateral maxilla
- involved bone can become malignant
- CN deficits b/c closing of foremen
- does NOT have hyperglolinemia
- Onset at Puberty
- No premature exfoliation of primary teeth
- Cotton wool appearance
- 50% hypercementosis
Malignant Bone Involvement
- spontaneous paresthesia of lip
- can see radiographicly
Nasolabial Cyst
- mucolabial, smooth swelling adjacent to maxillary lateral incisor
- Lots of respiratory epithelium lining this true cyst.
- External naris.
- soft tissue involvement, not bone
- histology: pseudostratified squamous epithelium
Odontgenic Keratocyst
- high recurrence
- most often intrabony, posterior mandible but can happen anywhere
- radiolucent, usually multilocular
- histology: palisaded basal cell layer and parakeratinized surface
Gardner Syndrome
- multiple facial osteomas and skin nodules
- hyperdontia, unerupted teeth
- Multiple GI polyps
- can happen young
Morsicatio Buccarum
- check and lip chewing
- buccal mucosa
- white, rough, tissue tags above and below the occlusal plane
Nevoid Basal Cell Carcinoma Syndrome
- onset in childhood
- cysts of the jaw - odontotogenic keratocysts with high recurrence rate
- basal cell carcinoma common
- RG - unilocular or multilocular lucencies
- calcification of the falx cerebri
Lymphoepithelial cyst
- common on ventral tongue/FOM
- circumscribed swelling
- pale, yellowish at times
Bell’s Palsy
- 7th nerve paralysis
- unilateral
inability to close of wink eyelid - last usually less than one month
Erythema Multiforme
- young adult males
- sudden onset and explosive
- triggered by drug or viral infection
- Crusted, bleeding vesicles, ulcers of vermilion
- if intraorl none on gingiva
- bulls-eye lesions on hands and feet
Pemphigus Vulgaris
- rare autoimmune disease that caused painful blisters
- basal cell later intact
- demonstrates immunoglobulin fluorescence
- IgG immunoglobulin
- positive Nikolsky sign
- Lips, palate and gingiva
Progressive Systemic Sclerosis
- widening of PDL
- no facial expressions
- fingers frozen in position
- notch at angle of mandible
- average opening 45mm
aspirin Burn
- white = coagulative necrosis of surface
- rubs off with difficulty
mucocele
- children and young adults
- trauma
- lower lip most common
- vesicle/bulla
- bluish in color
basal cell carcinoma
- painless ulcer with raised margins
- NOT INTRAORALLY
- papule with telangiectasia
- does not metastasize
Benign Migratory Glossitis
- Red, flat depapillated area of tongue
- white, keratin, cell debris
- comes and goes
- soreness of burning of mouth
- corticosteroid rinse
Ranula
- FOM swelling
- bluish
- mucin if aspirated
dentigerous cyst
- posterior mandible most common (3rd molars)
- can be ameloblastoma, SCC
- pericoronal radiolucency attached to CEJ of unerupted tooth
Antral Pseudocyst
- asymptomatic
- no treatment needed
- slight radiopaque, dome shaped in maxillary sinus
Parulis
- tooth needs RCT
- elevated reddish- yellow
- bad taste in mouth common
Eagle syndrome
- calcification of stylohyoid ligament
- CN impingement
Varices
- dilated vein - blue
- elderly
- can feel hard as a rock
Herpes Zoster
- vesicle change to ulcers
- unilateral distribution on skin and oral
- comes from dorsal root ganglion
dermoid cyst
- doughy
- anterior floor of mouth MIDLINE
- bluish yellow color
Primary Herpes Gingivostomatitis
- inflamed, enlarged marginal gingiva, bleeding
- vesicles to ulcers
- malaise
- low grade fever
- sore throat
- HSV
- hangs out before reactivation
- trigeminal ganglion
Crohn’s disease
- granulomatous gingivitis
- aphthous-like ulcers
- rectal bleeding
incisive canal cyst
- most common developmental non-odontogenic cyst
- vital teeth
- mx midline
- true cyst
- heart shaped radiolucency
actinic cheilitis
- vermilion board indistinct
- great potential for dysplasia
- Feels rough like sand paper.
- Scaling, crusting.
- High percentage turns into cancer.
white sponge nevus
- genodermatosis
- autosomal dominant
- moderately extensive thick, white folds of tissue
- bilateral buccal mucosa
- no eye involvement
Periapical Cemento-osseous Dysplasia
- middle aged black woman
- mandibular anterior vital teeth
- no pain or expansion
- multifocal periapical lucencies
Florid Cemento-Osseous Dysplasia
- multiple fibro-osseous
- in all 4 quads
- RL and radiopaque
- African american women
- not in mandibular anterior
Focal Cemento-osseous dysplasia
- single site
- 3rd-6th decade
- 90% female
- one round radiolucency to radiopaque
- posterior mandible
- no pain or expansion
- white female
Cheilitis Glandularis
- mucous minor salivary gland of lips inflamed
- mucus secretions
- premalignant condition - SCC
- Pt will talk about burning, tingling or weird sensation of lip
Oral hairy leukoplakia
- white, rough plaque on lateral border of tongue that doesn’t rub off
- Hypertrophy of filiform papillae
- HIV positive patient
- caused by Epstein-Barr virus
Lichen Planus
- middle age women most often
- purple, polgonal, pruritic papules
- white papule or coalescing - wickam’s striae
- Microscopic - hyperkeratosis, irregular epithelial proliferation in a “saw-tooth” pattern of rete pegs
- does not wipe off - reticular form
- erosive form wipes off
- hyperplastic - plaque like and doesnt wipe off
peripheral ossifying fibroma
- soft tissue lesion
- not in bone but makes osteoid/bone
- occurs in gingiva especially interdental papilla area
- scattered light opacities on radiograph
Calcifying Odontogenic cyst
- Not purely RL, b/c calcifying - salt and pepper appearence
- most likely to affect the anterior areas of the jaws
- most common in people in their second to third decades but can be seen at almost any age
- Gorlin cyst- histo GHOST CELLS!!
- lossed blue nucleus
Nicotine Stomatitis
- hard palate
- red, inflamed minor salivary gland ducts
tobacco use
cleidocranial dyplasia
- multiple unerupted supernumerary teeth
- retention of primary teeth
- missing clavical, frontal bossing, large head
Auriculotemporal syndrome
- Frey syndrome
- Due to parotid surgery, sweat gland nerves are hooked up to your parotid gland,
- so when you’re parotid salivates, it activates to make sweat instead.
actinomycosis
- soft tissue swelling with multiple draining fistulas
- sulfur granules
- woody consistency
condylar hyperplasia
- irregular elongated condyle
- chin deviates away from affected side upon closure
dens-in-dente
- dens invaginatus
- found most commonly in anterior mx lateral incisor
Periapical cyst and granuloma
- non-vital tooth at apex
- periapical lucency with radiopaque line
Ectodermal dysplasia
- exhibits missing teeth (hypodontia or anodontia)
- heat intolerance
- lack of hair and fingernails and eyebrows
Dentin dysplasia
- dentin abnormal with exposure
- draining fistulas
- misshapen teeth
- type 1 “rootless” teeth
- periapical lucencies
Lymphangioma
- lymph-filled superficial vessels
- most common cause of macroglossia (enlarged tongue)
Infectious mononucleosis
- lateral cervical swelling
- sore throat
- teenagers most common
- positive monospot test
- EBV associated
- palatal petechiae
Hemangioma
- hamartoma
- red to blue elevated lesions
- blanches and compressible
- collection of small or large vessles filled with RBC
Hypercementosis
- vital mandibular first molar
- generalized acromegaly
- radiopacity with intact PDL
- attached to root surface
Acquired Melanocytic nevus
- pigmentation that is not an amalgam tattoo
- biopsy taken
- junctional type most common to undergo malignant transformation
Keratoacanthoma
- Difficult to differentiate from squamous cell carcinoma of the face and lip
- sun-exposed skin
- keratin plug in the center of ulceration
- present for months and spontaneously resolves
Warthin’s tumor
- papillary cystadenoma lymphommatosum
- benign cystic tumor of the salivary glands
- most common in males and parotid gland
- not inside mouth
Vitamin C deficiency
- scurvy
- does not cause xerostomia
Sjogren’s syndrom
- autoimmune disorder
- elderly women
- dry eyes, dry mouth
- parotid swelling
Stafne Defect
- salivary gland depression defect
- developmental
- more in males
- asymptomatic
- vital teeth
- well demarcated lucency found near the angle of mandible below mandibular canal
Peutz-Jeghers Syndrome
- oral and paraoral
- pigments brown macules
- found on lips, tongue, buccal mucosa, vermilion
- intestinal polyposis
Osteosarcoma
- localized pain and swelling, tingling of lower lip
- onset late 20s to early 30s
- early radioluceny then opacity
- trabeculae changes,
- PDL symmetrical widening
- sunburst appearance radiographicly
- common in posterior mandible
Osteopetrosis
- massive overproduction of dense, nonvital bone of both jaws
- young adults
osteoma
- found at angle of mandible
- well circumscribed radiopacity
Necrotizing sialmetaplasia
- rapidly expanding ulcerative lesion
- deep ulcerations of palate
- usually benign, often painless, self-limiting, and resolves in about six to ten weeks.
multiple myeloma
- elderly males
- immunoglobulin spike
- multiple bone sites
- punched-out lucencies
Odontogenic myxoma
- young adult onset
- multilocular lucency with soap bubble pattern
- closely resemble ameloblastoma
desquamative gingivitis would be what three diseases
- pemphigoid
- pemphigus
- lichen planus
what does causes gingival hyperplasia
cyclosporine
nifedipine (Procardia)
Phenytoin (Dilantin)
How do you increase the intensity of an x-ray
milliamperage
double will double intensity of an x-ray beam
what controls contrast and penetrating characteristics of an x-ray
kilovoltage
Epulis Fissuratum
- Hyperplastic connective tissue like fibroma
- Associated with ill-fitting denture flange
- Treatment does NOT include antibiotic treatment