Oral Mucosa Flashcards

1
Q

what are the 2 basic tissues of oral mucosa

A

epithelium - superficial

CT - underlying

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2
Q

what protection does mucosa have

A

mechanical
chemical
bacterial
prevent dehydration

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3
Q

is the mucosa innervated and involved in sec

A

richly innervated

secretion

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4
Q

what are some features of mucosa

A
free gingiva 
attached gingiva
alveolar mucosa
mucogingival junction 
free gingival groove
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5
Q

where can masticatory mucosa be found

A

roof of mouth

gingiva upper and lower infant and behind teeth

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6
Q

where can lining mucosa be found

A

inside lips and sulci
posterior mouth - tonsils
ventral aspect tongue

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7
Q

where is some specialised mucosa

A

dorsum tongue

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8
Q

what si the structure of non keratinised lining mucosa

A

epithelium
lamina propria
submucosa
bone or muscle

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9
Q

what are imp features of non keratinised lining mucosa

A

undulating interface LP
rete pegs
no muscular mucosae
flexible

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10
Q

what does the epithelium layer of non keratinised lining mucosa consist of

A

superficial layer
intermediate layer
prickl cell layer
basal cell layer

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11
Q

why is the prickle cell layer calls

A

when fixation shrinks but still attached at desmosome attachments between cells

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12
Q

is the epi replaced

A

turnover v quick

all the time

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13
Q

what do al epi cells have

A

filaments

desmosomes

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14
Q

what is a feature of basal cells -

A

least differentiated

mitosis often visible

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15
Q

what do prickle cells contain

A

membrane coating granules

MCGs

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16
Q

what do the intermediate cell layer contain

A

MCGs discharge between cells

(GOO - waterproof) perm barriernd wholly effective

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17
Q

why is it clinical important

A

drug abs

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18
Q

what are in superficial layer cells

A

flattened cells
nuclei persist
not dehydrated therefore flexible

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19
Q

what is the structure of keratinised masticatory mucosa

A
epi 
rete pegs
lamina proppria 
- papillary layer
- reticular layer 
periosteum
bone
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20
Q

what are some imp features of keratinised masticatory mucosa

A
many rte pegs 
no submucosa
LP firm attach to bone 
resist compression 
relative immobile and mech tough
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21
Q

LA into lining mucosa

A

flexible

can be pain free if done properly

22
Q

LA into masticatory mucosa

A

tightly bound can hurt

23
Q

what is the structure of keratinised mucosa

A

keratinised layer
granular
prickle cell
basal cell

24
Q

what do basal cells like

A

non keratinsied epi

25
Q

what are the filaments in prickle cells organise into

A

bundles

tonofibrils

26
Q

wat are the granular cell layer cells

A

keratohyaline
assc wth tonofibirls
filaggrin - form matrix for filaments in keratinised layer

27
Q

in the granular cell layer what do the MCGs do

A

discharge contents sealing cells together
effective perm barrier
cells beyond barrier zone are dehydrate

28
Q

what are thee keratinised layer cells like

A

flattened cells squames
no organelle
contain filled with keratin
dehydrated and not flexible

29
Q

what is parakertainsiation

A

incomplete removal of organelles form the superficial layers
nuclei shrunk - pyknotic

30
Q

what is the epi turnover

A

5 days - junc epi
10-14 days- cheek
mast mucosa slower
rapid heal process

31
Q

what are some epi abnormalities

A

acanthosis

acanholysis

32
Q

what is acanthosis

A

hyperplasia of prickle cell layer - pcoriasis

33
Q

what is acanttholysis

A

disruption of intercellular connections

pemphigus

34
Q

how many cells in epi non keratinocytes

A

10%

35
Q

what do non keratinocytes lack

A

tonofibrils and desmosomes

36
Q

what are some examples of non kertancytes

A

merkel cols
melanocytes
langerhanns cells
inflammatory cells

37
Q

why call non keratinocytes called clear cells

A

light microscopic appearance

38
Q

when fix seething what happens

A

it shrinks

39
Q

what is a merkel cell

A

touch receptor link to nerves

40
Q

what is a melanocyte

A

dense melanosomes
melanin
pigmentation

41
Q

where are Merkel cells and melanocytes in epi

A

in basal layer

42
Q

in supra basal layer have what non pertained cells

A

langerhnns

inflam cells

43
Q

what are langerhanns cells

A

more superficial layers
dendritic
process antigenic material

44
Q

what are the inflammatory cell

A

transiently migrate into epi

lymphocytes common

45
Q

what does the lamina propria contain

A

is CT
collagen
- 90% type 1
- 8% type 2

fibroblasts
defence cells

46
Q

where is lamina propria loose

A

papillary layer

47
Q

where is lamina propria more organise

A

reticular layer

48
Q

what are some sensory innervations in CT

A

free nerve endings
krause end bulbs
ruffini corpuscles

49
Q

wha are some sensory innervation in epi

A

free nerve endings

merkel cells - neurone complexes

50
Q

what are the two layers of basal lamina

A

lamina lucida

  • thick
  • glycoprotein laminin

lamina densa

  • thick
  • type 4 collagen
51
Q

what re some features of basal lamina

A
basal cell
hemi-desmosomes
lamina lucida
lamina densa
anchoring filaments
collagen fibrils 
anchoring fibrils
52
Q

why is there a large surface interface area

A

disperses applied forces

metabolic interchange