Oral Mucosa

Question 1

what are the 2 basic tissues of oral mucosa

Answer 1

epithelium - superficial

CT - underlying

Question 2

what protection does mucosa have

Answer 2

mechanical
chemical
bacterial
prevent dehydration

Question 3

is the mucosa innervated and involved in sec

Answer 3

richly innervated

secretion

Question 4

what are some features of mucosa

Answer 4

free gingiva 
attached gingiva
alveolar mucosa
mucogingival junction 
free gingival groove

Question 5

where can masticatory mucosa be found

Answer 5

roof of mouth

gingiva upper and lower infant and behind teeth

Question 6

where can lining mucosa be found

Answer 6

inside lips and sulci
posterior mouth - tonsils
ventral aspect tongue

Question 7

where is some specialised mucosa

Answer 7

dorsum tongue

Question 8

what si the structure of non keratinised lining mucosa

Answer 8

epithelium
lamina propria
submucosa
bone or muscle

Question 9

what are imp features of non keratinised lining mucosa

Answer 9

undulating interface LP
rete pegs
no muscular mucosae
flexible

Question 10

what does the epithelium layer of non keratinised lining mucosa consist of

Answer 10

superficial layer
intermediate layer
prickl cell layer
basal cell layer

Question 11

why is the prickle cell layer calls

Answer 11

when fixation shrinks but still attached at desmosome attachments between cells

Question 12

is the epi replaced

Answer 12

turnover v quick

all the time

Question 13

what do al epi cells have

Answer 13

filaments

desmosomes

Question 14

what is a feature of basal cells -

Answer 14

least differentiated

mitosis often visible

Question 15

what do prickle cells contain

Answer 15

membrane coating granules

MCGs

Question 16

what do the intermediate cell layer contain

Answer 16

MCGs discharge between cells

(GOO - waterproof) perm barriernd wholly effective

Question 17

why is it clinical important

Answer 17

drug abs

Question 18

what are in superficial layer cells

Answer 18

flattened cells
nuclei persist
not dehydrated therefore flexible

Question 19

what is the structure of keratinised masticatory mucosa

Answer 19

epi 
rete pegs
lamina proppria 
- papillary layer
- reticular layer 
periosteum
bone

Question 20

what are some imp features of keratinised masticatory mucosa

Answer 20

many rte pegs 
no submucosa
LP firm attach to bone 
resist compression 
relative immobile and mech tough

Question 21

LA into lining mucosa

Answer 21

flexible

can be pain free if done properly

Question 22

LA into masticatory mucosa

Answer 22

tightly bound can hurt

Question 23

what is the structure of keratinised mucosa

Answer 23

keratinised layer
granular
prickle cell
basal cell

Question 24

what do basal cells like

Answer 24

non keratinsied epi

Question 25

what are the filaments in prickle cells organise into

Answer 25

bundles | tonofibrils

Question 26

wat are the granular cell layer cells

Answer 26

keratohyaline assc wth tonofibirls filaggrin - form matrix for filaments in keratinised layer

Question 27

in the granular cell layer what do the MCGs do

Answer 27

discharge contents sealing cells together effective perm barrier cells beyond barrier zone are dehydrate

Question 28

what are thee keratinised layer cells like

Answer 28

flattened cells squames no organelle contain filled with keratin dehydrated and not flexible

Question 29

what is parakertainsiation

Answer 29

incomplete removal of organelles form the superficial layers nuclei shrunk - pyknotic

Question 30

what is the epi turnover

Answer 30

5 days - junc epi 10-14 days- cheek mast mucosa slower rapid heal process

Question 31

what are some epi abnormalities

Answer 31

acanthosis | acanholysis

Question 32

what is acanthosis

Answer 32

hyperplasia of prickle cell layer - pcoriasis

Question 33

what is acanttholysis

Answer 33

disruption of intercellular connections | pemphigus

Question 34

how many cells in epi non keratinocytes

Answer 34

10%

Question 35

what do non keratinocytes lack

Answer 35

tonofibrils and desmosomes

Question 36

what are some examples of non kertancytes

Answer 36

merkel cols melanocytes langerhanns cells inflammatory cells

Question 37

why call non keratinocytes called clear cells

Answer 37

light microscopic appearance

Question 38

when fix seething what happens

Answer 38

it shrinks

Question 39

what is a merkel cell

Answer 39

touch receptor link to nerves

Question 40

what is a melanocyte

Answer 40

dense melanosomes melanin pigmentation

Question 41

where are Merkel cells and melanocytes in epi

Answer 41

in basal layer

Question 42

in supra basal layer have what non pertained cells

Answer 42

langerhnns | inflam cells

Question 43

what are langerhanns cells

Answer 43

more superficial layers dendritic process antigenic material

Question 44

what are the inflammatory cell

Answer 44

transiently migrate into epi | lymphocytes common

Question 45

what does the lamina propria contain

Answer 45

is CT collagen - 90% type 1 - 8% type 2 fibroblasts defence cells

Question 46

where is lamina propria loose

Answer 46

papillary layer

Question 47

where is lamina propria more organise

Answer 47

reticular layer

Question 48

what are some sensory innervations in CT

Answer 48

free nerve endings krause end bulbs ruffini corpuscles

Question 49

wha are some sensory innervation in epi

Answer 49

free nerve endings | merkel cells - neurone complexes

Question 50

what are the two layers of basal lamina

Answer 50

lamina lucida - thick - glycoprotein laminin lamina densa - thick - type 4 collagen

Question 51

what re some features of basal lamina

Answer 51

``` basal cell hemi-desmosomes lamina lucida lamina densa anchoring filaments collagen fibrils anchoring fibrils ```

Question 52

why is there a large surface interface area

Answer 52

disperses applied forces | metabolic interchange