Oral Manif Flashcards
Chronic inflammation
biofilm bacteria causing inflammation
produce cell inflammation mediators
internal stiffening can lead MI and stroke
years to elevated systemic inflammation lead to destructive effects on target tissues
systemic disease and the oral cavity
mucosal inflammation, ulceration, bleeding
opportunistic infections
xerostomia
poor wound healing, perio
hyperpituitarism - acromegaly
patient’s in 40’s enlarged hands and feet, deep voice (schwartzenager) enlarged maxilla and mandible separation of teeth and malocclusion thick lips and tongue
hyperthyroidism - grave’s disease
more common in women rosy complexion, sweating, osteoporosis bugging eyes premature loss of primary teeth, premature eruption of permanent teeth progressive caries and perio burning tongue
hypothyroidism
cretinism (kids), myxedema (adults)
autoimmune, iodine deficiency, drug induced
thick lips, enlarged tongue
delay eruption
hyperparathyroidism
primary (tumor) / secondary (kidney failure)
middle aged adults, women
elevated serum calcium and reduced serum phosphorous
uni or multilocular radiolucencies filled with giant cells
loss of lamina dura
loose teeth
hypoadrenalism
addison’s disease
autoimmune or tumor etiology
bronzing of the skin
melanotic macula said on oral mucosa
diabetes type I
early onset
destruction of beta cells of pancreas
insulin deficiency, requires insulin
poor wound healing, eyes, cardiovascular, kidneys, nerves
type II diabetes
late onset
insulin resistance (loss of receptors)
controlled by diet, exercise, oral hypogylcemics
poor wound healing, eyes, cardiovascular, kidneys, nerves
diabetes oral complications
candidiasis parotid gland enlargement xerostomia severe caries and perio abscesses and infections
anemia
reduction of circulating red blood cells associated with nutritional deficiency pallor of skin ulceration angular cheilitis erythema and atrophy burning tongue
specific anemias (thalassemia/mediterranean/cooley)
inherited (mediterranean cultures)
prominent cheekbones, prominent premaxilla, protrusion of anterior teeth
salt and pepper trabeculae, thin lamina dura, circular radiolucencies
sickle cell
inherited
weakness, shortness of breath, fatigue, joint pain, nausea
loss of trabeculae, large irregular marrow spaces
aplastic
after chemotherapy or radiation therapy
petechiae or purpuritic spots
polycythemia
increase in circulating red blood cells
more common in white men under stress
headache dizziness, pruritis
mucosa is deep red or purple, bleeds easily