Oral Exam: Anticoagulation

Question 1

Apixaban for new VTE

Answer 1

10mg PO BID x 1 week

5mg PO BID thereafter

Question 2

Rivaroxaban for new VTE

Answer 2

15mg PO BID x 3 weeks

20mg PO QD thereafter

Question 3

Warfarin dosing

Answer 3

Initial dose: 2-5mg daily
Adjust based on INR
Native valve INR goal: 2-3
Mechanical valve INR goal: 2.5-3.5

Question 4

Apixaban considerations

Answer 4

BID maintenance dosing
Less renal clearance
Does not need to be taken with food

Question 5

Rivaroxaban considerations

Answer 5

QD maintenance dosing
More renal clearance
Needs to be taken with a meal