Oral Developmental Biology: Odontogenesis 2

Question 1

Label this diagram in the bell stage:

Answer 1

Question 2

What does Dental Papilla cells mature into and then what does that then form?

Answer 2

DP cells mature into Odontoblasts • Form predentine then dentine

Question 3

What does Innner Enamel Epithelium mature into and what does that then form?

Answer 3

IEE cells mature into Ameloblasts • Form Enamel

Question 4

What is labelled in this crown stage?

Answer 4

Question 5

What is pre-dentine?

Answer 5

Is the organic matrix that makes up Dentine before it is calcified.

Question 6

What is Dentine?

Answer 6

Mineralised Pre-dentine!

Question 7

What is in Enamel?

Answer 7

Different proteins from Dentine. 2 groups: The Amelogenins which are multiple splice variants making up 90-95% Enamelins (or non amelogenins) making up 5-10%

Question 8

Answer 8

Question 9

What determines tooth shape?

Answer 9

Differential rates of cell division/maturation NOT by forces within the papilla, however….. Signal for tooth shape from dental papilla

Question 10

What determines what sort of tooth is found where?

Answer 10

Various transcription factors. MSX-1, MSX2, Dlx1/2, Barx-1 and Alx-3 determine what sort of tooth is found where.

Question 11

Reduced Enamel Epithelium happens when enamel formation is complete. What is its role?

Answer 11

1. protection of enamel surface from: • resorption • prevention of cementum formation
2. provide an epithelial lined pathway for eruption
3. Forms initial junctional epithelium….

Question 12

What are the following Dental Developmental Disturbances:

1. Hypodontia
2. Oligodontia
3. Anodontia

Answer 12

1. Hypodontia - tooth loss except 3rd molars
2. Oligodontia - more than 6 teeth missing
3. Anodontia - all teeth missing