Oral Cavity Path Flashcards

1
Q

Dental Caries

Pathologic Process and Epidemiological Significance (2)

A

Focal demineralization of enamel and dentin by acidic metabolites of sugars fermented by bacteria

Main cause of tooth loss before age 35
One of the most common diseases worldwide

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2
Q

Gingivitis

Description and Complications (2)

A

Inflammation of oral mucosa around teeth

Dental plaque: bacteria, salivary proteins and desquamated epithelial cells
Tartar: mineralized plaque

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3
Q
Periodontitis
Description (3), Complication and Associated Diseases (7)
A

Inflammation of the periodontal ligaments, alveolar bone and cementum

Destruction of ligaments leads to loosened/lost teeth

Leukemia
AIDS
Crohns
Diabetes
Downs Syndrome
Sarcoidosis
Neutrophil Defects
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4
Q
Aphthous Ulcers (Canker sore)
Characteristics (4)
A

Very painful
Recurrent
Superficial mucosal ulcers
Lined by a ring of erythema

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5
Q

Traumatic Fibroma

Cause and Description

A

Reactive proliferation from repetitive trauma

Submucosal nodular mass of fibrous connective tissue

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6
Q

Pyogenic Granuloma

Description (3), Progression, Populations (3)

A

Red/purple highly vascular inflammatory lesion found in the gingiva

Can progress to peripheral ossifying fibroma

Kids
Pregnant women
Young adults

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7
Q

Oral Cavity Infections with Presentations

HSV (2), Candida (3), Mucromycosis (1)

A

Herpes Simplex Virus
Acute herpetic gingivostomatitis (gingival sores)
Recurrent herpetic stomatitis (cold sores)

Candida albicans
pseudomembranous (thrush), erythematous, or hyperplastic

Mucormycosis
Hematogenous invasion of sinuses

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8
Q
Scarlet Fever
Oral Presentations (2)
A

Red tongue with prominent papillae (raspberry)

White tongue with hyperemic papillae (strawberry)

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9
Q

Measles

Oral Presentation

A

Koplik spots: buccal ulcerations around Stensen duct of parotid gland

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10
Q
Infectious mononucleosis
Oral Presentations (3), Diagnosis, Cause, Histology
A

Gray-white exudative membrane via pharyngitis/tonsilitis
Enlarged neck lymph nodes
Palatal petechiae

+ monospot test
EBV causes
Atypical lymphocytes

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11
Q
Diphtheria
Oral Presentation (4)
A

Dirty white, fibrinosuppurative inflammatory membrane over tonsils and retropharynx

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12
Q
HIV
Oral Presentations (4)
A

HSV
Candida
Kaposi Sarcoma
Hairy Leukoplakia

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13
Q

Leukoplakia vs Erythroplakia

Descriptions (2/5) and Risk of Complication

A

Leukoplakia
White plaque on lateral tongue that can’t be scraped off
Considered precancerous until proven otherwise

Erythroplakia
Red, vascular, slightly depressed, atypical lesion
**Much higher rate of malignant transformation

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14
Q
Classic Squamous Cell Carcinoma
Precursor Steps (4), Risk Factors (2), Morphology (4), Immunohistochemistry
A

Hyperplasia/Hyperkeratosis
Mild/Moderate dysplasia
Carcinoma in situ
Squamous cell carcinoma

Alcohol
Tobacco

Ulcerated, protruding masses with irregular and indurated borders

Cytokeratin positive

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15
Q

Odontogenic Keratocyst

Description (2)

A

Malignant cysts requiring complete surgical excision to avoid recurrence

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16
Q

HPV Associated Squamous Cell Carcinoma

Immunohistochemistry, Pathogenesis, Morphology (4) and Locations (3)

A

p16 positive

No precursor lesion

Ulcerated, protruding masses with irregular and indurated borders

Tonsils
Base of tongue
Pharynx