Oral Cavity Conditions Flashcards
Leukoplakia
- White patch in mouth that CANNOT be scraped off
- Hyperkeratosis of oral mucosa a/w local irritation
-> Ill-fitting dentures
-> Smoking
-> Alcohol
-> Eating strong spices
-> Bad dentition - Overall risk of malignancy: 6%
Variants of leukoplakia
- Erythroplakia
- Red patches in mouth
- Greater malignant potential - Oral hairy leukoplakia
- EBV related
- White patches (exophytic-looking) on lateral border of tongue
- A/w HIV and immunosuppression
Investigations for leukoplakia
Biopsy*
- May choose to tx with trial of antifungals for 2 weeks first
- 1-20% risk of malignancy
- 3% undergo malignant change in 5 years, more so in erythroplakia
Management for leukoplakia
- Regular review even if initial biopsy benign
- Laser ablation*
Lichen planus
T cell mediated inflammation (autoimmune) that can affect skin and oral cavity
Clinical features of lichen planus
- Variable lesions but may mimic hyperkeratosis
- White lace-like appearance
- Waxing or waning nature
- Painless
- Benign but has pre-malignant risk of 1-5%*
‘Lacy, reticulated pattern’
Management of lichen planus
- Topical/systemic steroids
- Immunosuppressants
Black hairy tongue
- Overgrowth of filiform papillae
- A/w smoking, poor oral hygiene, Abx use, C. albicans infx, xerostomia, LPR
Management of black hairy tongue
- Vigorous brushing of tongue to scrape these away or use a special tongue cleaner
- Resolves usually
Risk factors for squamous cell carcinoma of the mouth
6S factors
1. Smoking
2. Spirits
3. Sunlight
4. Sharp teeth (Chronic injury)
5. Sexually-acquired diseases (HPV, syphilis)
6. Spices
+ 7. Known leukoplakia/ erythroplakia (Premalignant conditions)
Most common oral cavity cancer
Squamous cell carcinoma
Most common site for oral cancer
Lateral border of tongue
Clinical features of SqCC
- Non-healing ulcer (>2 weeks, enlarging)
- Oral cavity mass
- Bleeding
- Otalgia (referred pain from pharyngeal plexus - posterior oropharynx)
- Dysarthria
- Difficulty chewing
- Trismus
- Change in denture fit (due to enlargement)
- Neck lump (nodal spread)
Investigations for SqCC
Management for SqCC
- Surgery +/- adjuvant chemo/RT
- Mandible split (mandibulotomy) or mandibulectomy
- Neck dissection