Oral cancer Flashcards

1
Q

what makes up 90% of all oral cancer

A

squamus cell carcinoma (epidormoid carcinoma)

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2
Q

how many new cases of SCC

A

30,000

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3
Q

how many people die due to SCC

A

9,000

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4
Q

what is the survival rate of SCC

A

49.5% (63% when placed with oropharyngeal cancer)

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5
Q

squamus cell carcinoma has a higher death rate then which other cancers

A

melanoma
cervical cancer
breast cancer

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6
Q

what is the target age group for SCC

A

50-70

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7
Q

males or females get SCC more often?

A

Males 2:1

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8
Q

risk factos of SCC (5)

A
  • tobacco products (smoke or smokeless)
  • alcohol abuse
  • immune system deficits
  • genetic defects
  • environmental contacts
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9
Q

what percentage of cases of oral cancer were smokers

A

75%

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10
Q

what is the critical deteminant when determining carcinogenicity in smokeless tobacco

A

moist vs dry snuff

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11
Q

how many packs a day must be smoked toequal to an alcoholics risk factor for cancer

A

2 packs per day

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12
Q

three effects of alcohol

A

drying agent
solvent effects
contaminants
(other factors may be nutrition deficiency, liver disease)

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13
Q

constitution of alcohol abuse

A

6 alcohol equivalents (one shot hard liquor, 6oz wine, 12oz beer)

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14
Q

reletive risks of alcohol and tobacco use

A
standard risk - 1
minimum smoking, drinking - 1
heavy smoking minimum drinking - 8
heavy drinking minimum smoking - 23
heavy smoking and drinking - 100
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15
Q

what factors may degrade immune system

A

aging
chronic nutritional deficiency
disease
therapeutic intervention

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16
Q

iron deficiency anemia may cause

A
  • increased susceptibility to carcinogens

- increased permeability of epithelium

17
Q

Vitamin A deficiency may cause

A

loss of protective/preventive role against precancer

18
Q

vitamin C deficiency may cause

A

decreased oxidation/reduction of compounds leads to persistence of noxious stimuli