Oral cancer Flashcards
what makes up 90% of all oral cancer
squamus cell carcinoma (epidormoid carcinoma)
how many new cases of SCC
30,000
how many people die due to SCC
9,000
what is the survival rate of SCC
49.5% (63% when placed with oropharyngeal cancer)
squamus cell carcinoma has a higher death rate then which other cancers
melanoma
cervical cancer
breast cancer
what is the target age group for SCC
50-70
males or females get SCC more often?
Males 2:1
risk factos of SCC (5)
- tobacco products (smoke or smokeless)
- alcohol abuse
- immune system deficits
- genetic defects
- environmental contacts
what percentage of cases of oral cancer were smokers
75%
what is the critical deteminant when determining carcinogenicity in smokeless tobacco
moist vs dry snuff
how many packs a day must be smoked toequal to an alcoholics risk factor for cancer
2 packs per day
three effects of alcohol
drying agent
solvent effects
contaminants
(other factors may be nutrition deficiency, liver disease)
constitution of alcohol abuse
6 alcohol equivalents (one shot hard liquor, 6oz wine, 12oz beer)
reletive risks of alcohol and tobacco use
standard risk - 1 minimum smoking, drinking - 1 heavy smoking minimum drinking - 8 heavy drinking minimum smoking - 23 heavy smoking and drinking - 100
what factors may degrade immune system
aging
chronic nutritional deficiency
disease
therapeutic intervention