Oral Antidiabetic Drugs Flashcards
1
Q
What is the primary mechanism of action of Sulfonylureas?
A
They stimulate insulin release from pancreatic Beta cells
2
Q
What diabetes type are prescribed sulfonylureas?
A
Type 2 diabetes
3
Q
What are the adverse reactions to Sulfonylureas?
A
Hypoglycemia, and as a result, weight gain
4
Q
Why are Sulfonylureas used with caution in the elderly?
A
Hypoglycemia
5
Q
Mechanism of action of metglitinides?
A
Binds to the SU receptor
6
Q
Metglitinides cause a brief but rapid spike in…?
A
Insulin
7
Q
What do Metiglinides get combined with?
A
Metformin
8
Q
What’s the predominant metiglinide prescribed?
A
Metformin
9
Q
What’s the first line therapy for patients with type 2 diabetes?
A
Metformin
