Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Biology > Option Topic: Human Physiology > Flashcards

Option Topic: Human Physiology Flashcards

You may prefer our related Brainscape-certified flashcards:
AP® Biology flashcards Biology 101 flashcards
1
Q

Why are hormones released when you are hungry or full

A
  1. Stretch receptors in the stomach or intestines
  2. Adipose tissue in response to fat storage
  3. Pancreas in response to blood sugar levels
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Which hormone grows hunger?

A

Ghrelin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Which hormone lowers hunger?

A

Leptin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Exocrine glands

A
  • Secrete substances via a duct onto the epithelial surface. (body, lumen of digestive tract)
  • composed of a cluster of secretory cells which form acinus
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are digestive juices controlled by

A
  • Nervous Mechanism
  • Hormonal Mechanism
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

The nervous mechanism in gastric secretion

A
  • The smell of food produces an immediate response
  • When food enters the stomach, sensed by stretch receptors
  • Signals sent to the brain trigger digestive hormones to sustain gastric stimulation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

The Hormonal Mechanism in gastric secretion

A
  • Gastrin is secreted into the bloodstream to stimulate the release of stomach acid
  • If Ph is low gastrin secretion is inhibited
  • When food passes through the small intestine duodenum releases digestive hormones: Secreyin + CCL stimulate the pancreas and liver to release digestive juice (neutralise stomach acid + bile emulsify fats)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the uses of Stomach Acid

A
  • dissolves chemical bonds within food molecules
  • pepsin is activated when pepsinogen is in acidic conditions
  • Prevents pathogenic infection by killing bacterial
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

How to protect the organs from stomach acid

A
  • Mucus layer in the stomach
  • Pancreas releases bicarbonate ions into the duodenum to neutralize stomach PH
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How is low PH environment maintained

A

Proton pumps secret H+ ions that combine with Cl- ions to form HCL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is PPL

A

proton pump inhibitors bind to the proton pump and prevent H+ ion secretion. Helps to raise PH and prevent gastric discomfort

May have more susceptibility to gastric infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Features of villi

A
  • Microvilli - increase SA
  • Rich blood supply - Fast transportation of material
  • Singular Layer - Fast diffuson
  • Lacteals - Absorbs lipids into the lymphatic system
  • Intestinal glands - Release digestive juices
  • Membrane protein - Helps transport digested material
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How do villi optimize the absorption of digested material

A

Tight junctions - Impermeable membrane to keep digestive fluid separated from tissue keeping a concentration gradient
Microvilli - Increased SA
Mitochondria - Provide ATP for active transport mechanisms
Pinocytotic Vesicles - non-specific uptake of fluids. Quick way of translocating

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Large VS Small intestine

A

Small absorbs usable food substances and does the final breakdown of food

Large absorbs water and dissolved minerals

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what is Roughage

A
  • Provides bulk in the intestine to help material move
  • Absorbs water to keep bowel movement
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is Egested

A

Bile Pigments, Epithelial Cells, Lignin, Cellulose, Bactertia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

how does blood flow in the liver?

A

Receives oxygenated blood through the hepatic artery and nutrient-rich blood from the portal vein

Deoxygenated blood is transported from the liver via the hepatic vein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What does the liver do?

A

process the nutrients absorbed from the gut

  • Storage of key nutrients
  • Detoxification of potentially harmful ingested substances
  • Produces plasma proteins to maintain sustainable osmotic conditions
  • Breakdown of red blood cells and production of bile salts
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Hepatic lobules

A
  • surrounded by hepatic artery (oxygen) and portal vein (nutrients)
  • Vessels drain into sinusoids which exchange material with hepatocytes
  • sinusoids drain into a central vein which feeds deoxygenated blood into the hepatic vein
  • Hepatocytes produce bile which is transported into bile ducts
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Sinusoids

A

blood vessel with an increased permeability which allows for larger molecules to leave and enter the bloodstream.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Carbohydrate metabolism

A

excess glucose is taken and stored as glycogen. And when there is too much glycogen is converted to other substances (fat)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Protein metabolism

A

amino acids cannot be stored so they are broken down into amine groups which are considered toxic. Therefor liver will remove them nd convert them into something harmless such as urea.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Fat Metabolism

A

stored by liver and exported to cells.

Low density lipoprotein - Transports cholesterol to cells (raise blood cholesterol levels)
High density lipoprotein - Transport excess cholesterol from cells back to the liver (lowers blood cholesterol levels)
Extra cholesterol is converted into bile salts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Detoxification in Liver

A
  1. converted into less harmful chemicals: mediated by cytochrome P450 enzyme group. Produce damage free radicals neutralized by antioxidants
  2. Converted chemicals attach to other substances. makes less harmful and is water soluble and easily excreted from the body
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Plasma protein

A

the protein present in the blood plasma. Produced through RER and exported into the blood by the Golgi complex

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Types of plasma protein

A
  • Albumins - Regulate osmotic pressure
  • Globulins - Act as a transport protein
  • Fibrinogens - involved in the clotting process
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Erythrocyte Recycling

A

Red blood cells have a short life span. And the liver is responsible for the breakdown and recycling of its components.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

What are Kupffer cells

A

Phagocytes that specialize in the breakdown of red blood cells

  1. Haemoglobin is broken down into globin and the iron-containing heme group
  2. Globin digested to produce amino acids
  3. Heme group are broken down into iron and bile pigment
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

What happens to the iron in Erythrocyte Recycling

A

Iron released must be complexed to avid oxidation

  • stored by the liver in the protein shell of ferritin
  • transported to bone marrow
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Endocrine Glands

A

Release chemicals into blood to help regulate functions. They are specific and slower in response compared to the nervous system.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Steroid Hormones

A
  • Lipophilic and diffuse across membranes of cells freely
  • They bind to cytoplasm receptors or nucleus to form active receptor hormone complexes. Wich binds to DNA acting as a transcription factor for gene expression
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

Peptide Hormones

A
  • Hydrophilic and lipophobic so they cannot move freely across the membrane
  • bind to receptors on the surface of the cell and activates a series of intracellular molecules called second messengers causing cell activity (signal transduction)
33
Q

What is the use of the second messenger in Peptide hormones

A

Enables the amplification of the initial signals since more molecules are activated

34
Q

Hypothalamus

A

Part of the brain that links to nervous and endocrine to maintain homeostasis
- Initiate endocrine
- Secrete releasing factors which target the anterior lobe of the pituitary gland
- secretes hormones directly into the blood into the posterior pituitary lobe

35
Q

Pituitary Gland

A

Direct contact with the blood portal system

endocrine - no duct

36
Q

Anterior Lobe

A

releasing factors cause the release of specific hormones into the bloodstream. These relate to glands

37
Q

Posterior Lobe

A

releases hormones produced by the hypothalamus itself. Relates to nerves

38
Q

What does the Pituitary gland control

A

Metabolism
Adult Development
Reproduction
Growth
Homeostasis

39
Q

What do growth hormones do

A

Reduce the formation of adipose cells acting indirectly with insulin growth factors. (Increase muscle mass and bone size)

40
Q

What is lactation regulated by

A

oxytocin and prolactin

41
Q

Prolactin in Lactation

A

production of milk
- Secreted by the anterior pituitary as a response to the release of PRH (prolactin-releasing hormone)
- Inhibited by progesterone (prevent milk during birth)

42
Q

Oxytocin in Lactation

A

release of milk
- produced in the hypothalamus
- triggered by sensory receptors in the breast by the suckling infant
- continuous oxytocin secretion until the infant stops feeding

43
Q

Specialised cardiac muscle cells

A
  • Contract without stimulation
  • Branched faster signalling
  • Not fused they are connected by gap junction at intercalated discs important as it allows for independent contraction
  • lots of mitochondria for aerobic respiration
44
Q

sinoatrial node

A

A cluster of cells in the right atrium acts as a primary pacemaker which controls the rate of heartbeat. Electrical signals sent out and stimulate contraction on atrial walls simultaneously

45
Q

Connective tissue between atria and ventricles

A

helps to anchor valves and cant conduct electrical signals so second node must be used

46
Q

atrioventricular node

A

second node that separates atrial and ventricular contractions. Helps with electrical signals however slower than sinoatrial

47
Q

Why is the delay in contractions between the atrioventricular and sinoatrial nodes important

A

Allows blood to fill up ventricles before the valves close

48
Q

Ventricular Contraction

A

sends signals down the septum by a specialised bundle of cardiomyocytes (bundle of his). Causing it to contact and ensuring contraction begins in the bottom forcing blood up

49
Q

Diastole

A

A period of Heart relaxing after contraction to fill with blood. Stops muscle from becoming fatigued

50
Q

Atrioventricular valves

A

(tricuspid and bicuspid)
Stops it flow back into atria

51
Q

Semilunar valves

A

(pulmonary and aortic)
Stops flow back into ventricles

52
Q

What is the first heart sound caused by

A

closure of the atrioventricular valves

53
Q

What is the second heart sound caused by

A

closure of the semilunar valves

54
Q

What is a p Wave

A

depolarisation of the atria

55
Q

what is a QRS complex

A

depolarisation of the ventricles

56
Q

what is a T wave

A

repolarisation of the ventricles

57
Q

Cardiac output equation

A

Heart Rate x Stroke Volume

58
Q

How is heart rate increased

A

sympathetic nervous system

59
Q

How is heart rate decreased

A

parasympathetic stimulation

60
Q

Systolic blood pressure

A

Higher shows pressure following contraction of the heart

61
Q

Diastolic blood pressure

A

Lower shows pressure of the heart when it relaxes between beats

62
Q

Type 1 Pneumocyte

A

mediate gas exchange with the bloodstream therefor is thin

63
Q

Type 2 Pneumocyte

A

secretes pulmonary surfactant to reduce surface tension

64
Q

alveolar air space

A

a dense network of capillaries that transport respiratory gases in the lungs

65
Q

cooperative binding

A

makes o2 binding to haemoglobin easier as every time o2 binds it alters it slightly. Higher affinity for o2 in oxygen-rich areas (oxygen loading) vs low affinity in oxygen-poor (oxygen unloading)

66
Q

why is the saturation of haemoglobin not linear?

A

Because binding potential changes with each additional O2 molecule

67
Q

Adult Haemoglobin dissociation curve

A

Sigmoidal (s-curve)
- Low saturation of haemoglobin when o2 levels low and vise-versa

68
Q

Fetal Haemoglobin dissociation curve

A

Has a higher affinity for oxygen so the dissociation curve shits to left
- Therefore it will load o2 when an adult is unloading

69
Q

Myoglobin

A

an oxygen-binding molecule that is found in skeletal muscle tissue and is not capable of cooperative binding. The curve is logarithmic.
- Saturated at low oxygen levels as it has a high affinity
- hold onto its o2 supply until levels in the muscles are very low

70
Q

How is co2 transported

A
  • Bound to haemoglobin
  • dissolved into water (very little)
  • converted into carbonic acid (most)
71
Q

Transport as Carbonic Acid

A
  1. co2 combines with h2o to form carbonic acid
  2. dissociated from h+ and bicarbonate
  3. bicarbonate pumped out cl- comes in
  4. bicarbonate with sodium in blood plasma form sodium bicarbonate which travels to the lungs
  5. H+ makes less alkali which means haemoglobin releases o2 and absorbs H+ to maintain PH
  6. Blood reaches the lungs bicarbonate is pumped back and the process reversed
72
Q

Chemoreceptors

A

detect PH change

73
Q

How do lungs regulate blood PH

A

Regulate amount of Co2 In the blood stream by changing ventilation

74
Q

How do kidneys regulate blood PH

A

Control reabsorption of bicarbonate ions

75
Q

Bohr Shift

A

the bohr effect is when there is a decrease in PH and its shifts the oxygen dissociation to the right as haemoglobin releases oxygen.

76
Q

How does metabolism affect the release of oxygen

A

Increased metabolism will result in a greater release of co2 as haemoglobin is promoted to release its o2 at its greatest needs

77
Q

Central chemoreceptors

A

control respiration by detecting changes in co2

78
Q

Peripheral chemoreceptors

A

detect CO2 levels, as well as O2 levels and blood pH

79
Q

miotic index

A

pmat/pmat+Interphase

Biology (12 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions