Opthalmology Flashcards
Uveitis
- Significance
Uvea significance
- Most vascular tissue in body
- Host of insults
- Autoimmune
- Infectious - Relationship to retina
- Supply
- Inflammation
Uvea
- Structure
Uvea
- Iris
- Cilliary body
- Chorea
Cilliary body
- Functions
- Inflammation
Cilliary body
- Functions
- Aqueous humour production
- Lens control
- Inflammation
3. Ciclitis/ intermediate uveitis
Uveitis
- Causes
Uveitis causes
- Unknown
- Autoimmune
- Infectious
- Traumatic
Uveitis classifications
Uveitis classifications
- Anterior
- Iritis - Intermediate
- Ciclitis - Posterior
- Choroiditis
Keratic precipitates
- Classes
Keratic precipitates
- Classes
- Granulomatous
- Non-granulomatous
Aqueous humour
- direction of currents
Aqueous humour
- direction of currents
- Convection to anterior
- Gravity to inferior
Anterior uveitis
- Symptoms
Anterior uveitis
- Symptoms
- Pain
- dull, orbital - Redness
- Vision
- Blurred/reduces - Flare
- floating leukocytes
Anterior chamber
- how to detect cells
Anterior chamber
- Detecting cells
- Dark room
- Thin beam of light
- Slit lamp - Cells seen
- Inflammatory exudate in aqueous
- usually 99% water - Beam seen (flare)
- Proteins in aqueous
Anterior uveitis
- signs
Anterior uveitis
- Posterior Synechiae
- Circumcorneal congestion
- Keratic precipitates
- Hypopyon
- Fibrin meniscus on lower iris
Intermediate uveitis
- Symptoms
Intermediate uveitis
- Symptoms
- Blurring of vision
- Floaters
Intermediate uveitis
- Signs
Intermediate uveitis
- Signs
- Cells in vitreous
- Snow balls
- Snow banking
- Sheathing of blood vessels
- Macular oedema
Macular oedema
Ix
Macular oedema ix
- OCT
Posterior uveitis
- Symptoms
Posterior uveitis
- Symptoms
- Blurring of vision
- Floaters
Posterior uveitis
- Signs
Posterior uveitis
- Signs
- Reduced acuity
- Light sensitivity
- Reduced colour vision
- Reduced vision in dark (nyctalopia)
CMV retinitis
- Significance
CMV retinitis
- Significance
- Immunosuppression
- HIV
- Transplant/chemo
Uveitis treatment
- Infectious Vs non infectious
Uveitis treatment
- Infectious Vs non infectious
- Treat both with steroid
- Scarring and inflammation is most significant factor - Treat with ABx first if infectious
Uveitis
- Ix
Uveitis
- Ix
- FBC U&E LFT
- Q Gold
- TB - Treponemal antibody
- Syphilis
Anterior uveitis
- Tx
Anterior uveitis
- Tx
- Topical steroids
- Subconjunctival steroids - Cycloplegics
Steroid eye drops
- ADRs
Steroid eye drops
- ADRs
- Glaucoma
- Gradual rise in pressure
- Insidious
- Irreversible - Cataracts
- Posteror sub-capsular
- Breadcrumb appearance
Intermediate and posterior uveitis
- Tx
Intermediate and posterior uveitis
- Tx
- Periocular steroids
- Intravitreal steroid implants
- Ozurdex
+Adjuncts - Pulse therapy
- Oral steroids
- Immunosuppression
- Better ADRs than steroids - Specific antimicrobial
Steroids
- Dangerous ADRs
Systemic steroids
- Dangerous ADRs
- Hyperglycaemia
- HTN
- Immunosuppression
- Osteoporosis
- Cushings
- Anxiety and irritability
Anterior Uveitis
- Complications
Anterior Uveitis
- Complications
- Posterior Synechiae
- Pupillary membrane
- Ocular hypertension
- Glaucoma - Hypotonia
- Cataract
- Cystoid macular oedema
Posterior uveitis
- Complications
Posterior uveitis
- Complications
- Retinal detachment
- Posterior Synechiae
- Scarring
- Glaucoma
High ocular pressure in uveitis
- Tx
High ocular pressure
- Tx
- Steroids
- Take baseline level (can increase)
- Priority is inflammation
Sympathetic opthalmitis
- Pathology
Sympathetic opthalmitis
- Trauma to eye
- Antigens to uveal pigment
- Inflammation in contralateral eye
- Vitiligo patches
- Deafness
- Meningism
Bony orbit
- Border names
Bony orbit borders
- Medial wall
- Lateral wall
- Floor
- Roof
Orbital foramina
- and contents
Orbital foramina
- Optic foramen
- nerve - Superior orbital fissure
- most vessels - Infra-orbital foramen
- Infra-orbital nerve
- Infra orbital artery - Supra orbital notch
- supra orbital nerve
5, Lacrimal groove
- Naso-lacrimal duct
- Lacrimal gland fossa
- Lacrimal gland
Orbital bones
Orbital bones
- Roof
- frontal - Lateral wall
- zygomatic
- sphenoid - Medial
- lesser sphenoid
- ethemoid
- Lacrimal bone
- nasal process of maxilla - Floor
- maxilla
Nasal duct
- Opening
Nasal duct opening
- Below inferior meatus
Orbital compartment syndrome
Orbital compartment syndrome
- Retrobulbar haemorrhage
- Proptosis
- Pain
- Blindness
- Ophthalmoplegia
- Miosis
Orbital septum
- Continuous with…
Orbital septum
- Continuous with periosteum of orbit
Horner’s syndrome
- Muscle
Horner’s syndrome
- Muscle
Superior tarsal muscle
Blowout fracture
- Symptoms
Blowout fracture
- Symptoms
- Pain
- Numbness to cheek, upper lip and gum
- Infra-orbital nerve
Blowout fracture
- Pathology
Blowout fracture
- Eye breaks bones
- medial
- inferior - Infra-orbital nerve damage
Stye Vs Chalazion (meimobian cyst)
Stye Vs Chalazion (meimobian cyst)
- Sebaceous
- Meimobian
Orbital Growths
- inside Vs Outside cone
Orbital Growths
- inside Vs Outside cone
- Axial proptosis
- Non-axial proptosis
Proptosis and lid-retraction
- Cause
Proptosis and lid-retraction
- Cause
- Thyroid eye disease
- Effects the muscles
Superior rectus and levator
- share…
Superior rectus and levator
- share…
Tendon sheath
Ocular muscles
- insertion
Ocular muscles
- insertion
- Rectus in front of axis
- Oblique behind axis
Sixth nerve palsy
- Anatomy
Sixth nerve palsy
- Anatomy
- Small nerve
- Passes over the clivus
- Easily compressed
Black on the eye
Black on the eye
- Choroid
Slit lamp
- 3D viewing
Slit lamp
- 3D viewing
- View straight ahead
- Light beam at an angle
Fundus
- Blind spot area
- No vessels area
Fundus
- Optic nerve
- Blind spot area - Fovea
- No vessels area
Eye symptoms
Eye symptoms
- Foreign body sensation
- Photophobia
- Eye Pain
- Headache
- Lid irritation
Foreign body
- How to evert
Evert an eye
- Look down
- Cotton bud
- Pull up and over
Eye symptom
- Foreign body sensation
Eye symptom
- Foreign body sensation
- Foreign body
- Corneal abrasion
Eye symptoms
- Photophobia ddx
Photophobia
- Meningitis
- Iritis
- Migraine
Photophobia vs light sensitivity
Photophobia vs light sensitivity
- Discomfort -> Photophobia
Eye pain
- DDX
Eye pain ddx
- Acute angle glaucoma
- Trauma
- Orbital cellulitis
- Scleritis
- Optic neuritis
- Corneal abrasion
Ophthalmology
- Headaches ddx
Ophthalmology
- Headaches ddx
- Migraine
- Cluster headache
- Eye watering - Trigeminal neuralgia
- ICP
- VI palsy
- Bilateral optic disc swelling (papilloedema)
- Postural change
- Presence on waking
- Pulsatile tinnitus - GCA
- Temporal and tender
- Jaw claudication
- Scalp tenderness
- Eye exam and markers
Lid irritation
Ddx
Lid irritation
Ddx
- Stye
- Follicle/seb gland
- Edge of eyelid and sore
- Fusillic acid ointment - Chalazion
- Meim gland
- Anywhere and painless
- Warm compress - Blepharitis
- Meimobian gland disease
- Eczema/skin conditions
Conjunctivitis
- causes and features
Conjunctivitis
- Allergic
1. Bilateral
2. Trigger linked
3. Itchy - Viral
1. Often bilateral
2. Coryzal symptoms
3. Watery discharge - Bacterial
1. Generally unilateral
2. Purulent discharge
Visual disturbances
- Generalised blurring ddx
Visual disturbances
- Generalised blurring ddx
- Refractive errors
- Cataracts
- Medications
- steroids
- tetracycline - Hormonal
- pregnancy
- period
Ophthalmology
- Central blurring ddx
Ophthalmology
- Central blurring ddx
- Macular diseases
- Age related
- Diabetic T2 - Drugs
- Ethambutol
- Hydroxychloroquine
- Tamoxifen (deposits)
Ophthalmology
- Black spots, blobs, and curtains
Ophthalmology
- Black spots, blobs, and curtains
- Vitreous
- Retina traction and detachment
- Flashing (immediate or ongoing) - TIA
- Transient!
Retina tear pathology
Retina tear pathology
- Vitreous traction
- Retina hole
- Vitreous behind retina
- Retina detachment
Double vision
- DDx
Double vision
-DDx
- Binocular
- NMJ
- Thyroid - Monocular
- In eye
- Chalazion/stye/abrasion
- Detachment
- Vitreous - Vertical or horizontal?
- Nerves involved
- Muscles involved? (Thyroid)
Ophthalmology
- Colour changes ddx
Ophthalmology
- Colour changes ddx
- Optic nerve disease
- Unilateral cataract
- Red desaturation (unilateral)
- Optic neuritis
Ophthalmology
- Co-morbidities
Ophthalmology
- Co-morbidities
- Diabetes
- Retina, CN palsy, ifct, vascular occlusion - HTN
- Thyroid
- retraction, lag, dry eye, neuropathy, motility - Ankylosing s
- Iritis
- Steroid SEs - Arthritis
- RA, PA
Opthalmology Ix
Opthalmology Ix
- Field test
- OCT
- Blood
Visual tests
Visual tests
- Snellen
- Near visual acuity test
- Amsler grid
- Ishihara colour grid
Visual tests
- glasses
Visual tests
- glasses
- Best corrected vision
- Distance glasses/reading glasses
Testing eyes
- binocular/monocular
Testing eyes
- binocular/monocular
- Each eye
- Eye occluder - AND both eyes
Recording vision
- numerator and denominator
Recording vision
- Numerator is distance
- Denominator is reading
Eye test
- Escalating tests
Eye test
- Failing tests
- 6m, pinhole, 3m, 1m
- Fingers
- Hand movements
- let me know when it stops - Light projection
- Top/bottom
- Left/right - Light perception
- say yes when you see the light shining
Pupil exam
- 5 Stages
Pupil exam
- 5 Stages
STAND TO SIDE
- Inspection
- Direct light
- Indirect light
- Consensual - Swinging lights
- Accommodation
Pupil abnormalities
Pupil abnormalities
- Drugs
- Opiates
- Drops - Horner’s
- III
Swinging light test
- Pathology
- Method
Swinging light test
- Pathology (Afferent pathway)
Comparative defect L Vs R
- Retina
- Nerve - Method
- Swing over bridge of nose
- 1,2,3 seconds
Visual field confrontation
- Peripheral method
Visual field confrontation
- Peripheral method
- Arm’s length
- Cover one eye
- examiner same corresponding - How many fingers
- Keep looking at eye
- count fingers in field - Can you see pin?
- keep looking at my eye - Keep your hand.
- I will swap hands to use other hand
Visual field confrontation
- Central vision
Visual field confrontation
- Central vision
- Red pin
- Cover eye
- Start at centre
- Move very slowly
- Acknowledge blind spot
- Acknowledge return of pin
Fundoscopy
- Use
Fundoscopy
- Use
- Green on button
- Check position
- examine at 0 - Use diffuse beam in dark
Or smallest beam - Approach patient from the side
- Can I rest my hand on your forehead
- Quick red reflex
- Very close to eye
- follow blood vessels
- reach optic disc
Glaucoma
- Definition
Glaucoma
- Definition
- Group of conditions
- Progressive optic neuropathy
- Optic nerve damage
- Visual field defects
- With/without pressure changes
Glaucoma
- Definition
Glaucoma
- Definition
- Group of conditions
- Progressive optic neuropathy
- Optic nerve damage
- Visual field defects
- With/without pressure changes
Glaucoma
- World significance
Glaucoma
- World significance
- Lead cause of Irreversible blindness
Glaucoma
- World significance
Glaucoma
- World significance
- Lead cause of Irreversible blindness
Glaucoma
- World significance
Glaucoma
- World significance
- Lead cause of Irreversible blindness
Glaucoma
- World significance
Glaucoma
- World significance
- Lead cause of Irreversible blindness
Glaucoma
- progression
Glaucoma
- progression
- Nasal step/temporal wedge
- Arcuate
- Tunnel vision
- Complete field loss
Glaucoma
- presentation
Glaucoma
- presentation
- Bumping things
- Tripping and falling
Glaucoma
DDx
Glaucoma
DDx
- GCA
- Anterior ischemic optic neuropathy
Glaucoma
- Pathophysiology
Glaucoma
- Pathophysiology
- Blockage of aqueous drainage
- Poor blood supply to optic nerve
Aqueous humour
- Function
Aqueous humour
- Function
- Nutrients to cornea
- Waste from cornea
Glaucoma
- Disc signs
Glaucoma
- Disc signs
- Cup to disc ratio increase
- Bayonetting of blood vessels
Glaucoma
- Types
Glaucoma
- Types
- Acute angle closure
- primary or secondary
- PAGG - Open angle glaucoma
- primary/secondary
- POAG
- NTG, PXF, PG - Developmental glaucoma
- congenital
- reiters - Secondary
- traumatic
- uveitic
- steroid
Open angle glaucoma
RFs
Open angle glaucoma
RFs
- IOP
- Age
- African descent
- FHx
- Myopia
Angle closure glaucoma
RFs
Angle closure glaucoma
RFs
- Raised IOP
- Age
- Far East/Inuits
- Family history
- Hyperopia
Glaucoma
- Tx principle
Glaucoma
-Tx principle
- Increase outflow
- Reduce inflow
IOP
- Normal range
IOP
- Normal range
- Caucasian
- 10-21mmHg (mean 16) - Black
- Higher
- greater Central Corneal Thickness
IOP
- Measurement
IOP
- Measurement
- Goldmannn Mires
- inside of rings just touch
IOP
- Reduction measures
IOP
- Reduction measures
- Laser
- Trabeculoplasty
- Cyclodiode - Drops
- Prostaglandins analogue
- Beta blockers
- Carbonic anhydrase inhibitors
- Alpha 2 antagonists - Surgery
- Trabeculectomy
(Enophthalmitis risk lifelong)
- Bleb
Acute closed angle glaucoma
- Ss
Acute closed angle glaucoma
Sx
Red eye
Pain
Blue tinged cornea
Acute closed angle glaucoma
- Mx
Acute closed angle glaucoma
- Mx
- Stat IV Acetazolamide
- Laser peripheral iridotomy
Glaucoma medication
- ADRs
Glaucoma medication
- ADRs
- Red eyes
Poor vision
- Three questions
Poor vision
- Three questions
- Onset and consistency
- Distance
- Glasses? Recent eye test?
Optic refection
1. Cornea
2. Lens
3. Axial length
Optic refection
- Cornea
- 40 dioptres - Lens
- 20 dioptres - Axial length
- 23mm
Accommodation reflex
- effect
Accommodation reflex
- effect
- Near distance light
- not parallel like distant light - Lens changes to refract light
Refractive errors
3 types
Refractive errors
3 types
- Anomalous axial length
- long or short sighted
- most common - Anomalous corneal power
- eg after corneal graft/transplant - Physiological? Pathological?
Refractive errors
- Myopia
- Sight
- Pathology
- Management
Myopia
- Sight
- Short sighted - Pathophysiology
- Long axial length
(or high power cornea) - Management
- Concave lenses
Refractive errors
- Hypermetropia
- Sight
- Pathology
- Management
Refractive errors
- Hypermetropia
- Sight
- Long- sighted - Pathology
- Short axial length
Or low powered cornea - Management
- Corrected with convex lens
Refractive errors
- Astigmatism
- Sight
- Pathology
- Management
Refractive errors
- Astigmatism
- Sight
- Two foci
- Blurred vision - Pathology
- Two axes of curvature
- Two foci - Management
- Spectacle undercorrection
- Spectacle over correction
- Refractive surgery
Presbyopia
- Pathology
- Mx
Presbyopia
- Pathology
1. Old eye
2. Declining amplitude of accommodation - Mx
1. Reading glasses
2. Bifocals/varifocals
Logarithmic chart
- use
Logarithmic chart
- use
- Precise for treatments requiring a measure
Eg. Macular degeneration
Assessment of refraction
- examination
Assessment of refraction
- Retinoscope
(Automated or manual)
Refraction in children
1 Squint DDx
2 Assessment
3 Mx
Refraction in children
- Squint
- Hypermetropia? - Assessment
- Retinoscopy under cycoplegia - Occlusion
- Patch to make squinting eye develop
- Diary for balancing eyes
- Glasses for Hypermetropia
Diabetic retinopathy
- RFs
Diabetic retinopathy
- RFs
- Duration of disease
- Glycemic control
- HTN
- Nephropathy
5.Pregnancy
6. Obesity
7. Smoking
Diabetic retinopathy
- Pathogenesis
Diabetic retinopathy
- Pathogenesis
- Occlusion & Ischaemia
2.IRMA
- intra retinal microvascular abnormalities
- Cotton wool spots
- Irregular retinal veins
- venous beading - Lipid collection
- Oedema
Diabetic retinopathy
- Leakage vs Occlusion
Diabetic retinopathy
- Leakage vs Occlusion
- Leakage
1. Loss of pericytes - Occlusion
1. BM thickening
2. Endothelial damage
3. RBC changes & rouleaux
4. Platelet aggregation
Diabetic retinopathy stages
Diabetic retinopathy stages
- Background
- Pre proliferative
- Proliferative
Background Diabetic Retinopathy
- Features
- Management
Background diabetic retinopathy
- Features
1. Micro aneurysm
2. Dot and blot haemorrhages
- Hard exudate
- Cotton wool spots
Management
- Observation
Diabetic retinopathy
- Pre-proliferative features
- Management
Diabetic retinopathy
- Pre-proliferative features
1.IRMA
- Intra-retinal microvascular abnormalities
- Venous loops
- Venous beading
- Clusters of large blot haemorrhages
- Multiple CW Spots
Management
- FU 4/12
Diabetic retinopathy
- Proliferative phase
Criteria
Diabetic retinopathy
- Proliferative phase
- NVD
- Neo-Vascularisation of the Disc - > 1/3 of NVD
- or any vitreous haemorrhage - NVE (neo-vasc elsewhere)
- >1/2 disk area
- with vitreous or pre-retinal haemorrhage
Proliferative Diabetic retinopathy
- Treatment
Proliferative Diabetic retinopathy
- Treatment
- Pan-Retinal-Photocoagulation (PRP)
- Within 2 weeks
Diabetic maculopathy
- Six classifications
Diabetic maculopathoes
- Focal
- Diffuse
- Ischemic
- Mixed
- CSMO
- Clinically significant macular oedema - Centrally involving
Diabetic maculopathy
- Focal
- Features
- Treatment
Diabetic maculopathy
Focal
- Features
1 Well circumscribed areas of leakage
2 Oedema
3 Full/part rings of exudates - surrounding micro aneurysm
- Treatment
1 Focal laser
Diabetic maculopathy
- Diffuse
- Features
- Treatment
Diabetic maculopathy
Diffuse
- Features
1. Diffuse retinal thickness
2. Cystoid oedema
3. MA - Treatment
1. Grid laser
Diabetic maculopathy
-Ischaemic
- Features
- Treatment
Diabetic maculopathy Ischemic
- Features
1. Reduced VA
2. Normal clinically
3. Macular ischemia on FFA - Management
1. Observe
Clinically significant macular oedema
- Definition
- Mx
Clinically significant macular oedema
- Definition
1. retinal thickening
2. within 500 microns of fovea
Mx
1. Anti VEGF injections
2. Intra vitreal steroid implants
Diabetes
- ocular complications
Diabetes
- ocular complications
- Retinopathy
- Iridopathy
- Unstable refraction
- Orbital infection
- Ocular ischaemic syndrome
- Recurrent stye
Retinopathy treatment
1. Background
2. Pre-proliferative
3. Proliferative
- Active
- Stable
- DMO
Retinopathy treatment
- Background
- 9-12/12 hospital FU - Pre-proliferative
- 4-6/12 FU - Proliferative
- Active
( PPR i 2/52)
- Stable
4-6/12 FU
- DMO
(Macular laser and PRP +- anti VEGF +- steroid implants)
Vitreous haemorrhage
1 sx
- Mx
Vitreous haemorrhage
1 sx
- Mx
- PRP same day for 2/52
- Vitrectomy +endolaser + anti VEGF if persistent
Rubeosis
Sx
Tx
Rubeosis
Sx
Tx
Pupil reflexes
- APD
- RAPD
Pupil reflexes
- APD
- Afferent pupillary defect - RAPD
- Relative afferent pupillary defect
- Swinging light reflex test
Afferent pupillary defects
- Causes
Afferent pupillary defects
- Causes
- Optic neuritis
- Demyelination
- Trauma
- Tumours
- Retinal abnormality
- Retinal detachment
- Glaucoma
- Artery/vein occlusion
3rd nerve palsy
- Presentation
3rd nerve palsy
- Presentation
- Binocular diplopia
- Anisocoria
- Ptosis
- Compensation
- Abnormal head posture
- Turn to one side
CN III Palsy
- Differentials
CN III Palsy
- Differentials
- Microvascular
- DM
- HTN - Trauma
- SoL
- Aneurysm (PCom.Art.)
- ICP
- Horner’s
- Myasthenia gravis
- Thyroid eye
- Inter-nuclear ophthalmoplegia
Papilledema
- S&S
- DDx
Papilledema
- S&S
1. Headaches - Worse on leaning forward
2. N&V
3. Visual changes and defects - DDx
1. SoL
2. Trauma
3. Haemorrhage
4. IIH - High BMI
- COCP
- Tetracycline
- Venous sinus thrombosis
- Perform MR venogram
Optic neuritis
- S&S
- Ix
- Tx
Optic neuritis
- S&S
0. Pain on eye movements
1. RAPD
2. Poor colour vision
3. Large blind spot - Ix
1. MRI - Tx
1. Steroids
Pediatric visual tests
- Charts
Pediatric visual tests
- Charts
- Sheridan Gardner Test
- Picture cards - Age-dependent
- Observation
- Fixing on objects
- Following objects - Refractive errors
- Cycloplegia
Red Reflex
- Ix
- DDx
Red Reflex
- Ix
1. Opthalmoscope
- Direct/indirect white reflex
- DDx
1. Cataracts - TORCH
- Galacktokinase
- DM
- Coats disease
- Telangiectic neo-vascular disease - Retinoblastoma
- RoP
- Retinal detachment
Squint/Strabismus
- Types
- Complications
Squint/Strabismus
- Types
0. Pseudo-squint
- In-turn-esotropia
- Out-turn-exotropia
- Hypo/hypertropia
- Complications
1. Amblyopia
2. Refractive error
Squint
- Examinations
Squint
- Examinations
- Cover test
- Cover one eye - Cover-uncover test
- Quickly moving
- For latent squint (when shut)
Strabismus
- DDx
Strabismus
- DDx
- Coloboma (keyhole pupil)
- Failure of optic fissure to close
- Nystagmus and squints - Ptosis
- Horner’s syndrome
- Neuroblastoma
- Syringomyelia
- Pheochromocytoma
Epiphora
- Pathology
- Mx
Epiphora
- Pathology
1. Nasolacrimal duct non-canalisation
2. Watery eye - Mx
1. Self-resolving in first year
2. Reassure and massage
- Syringe and probe
LogMAR Chart
- Scoring
- Advantages
LogMAR Chart
- Scoring
1. 0.1 per line
2. 0.02 per letter - Advantages
1. Uniform reduction in size
2. Reduced letter crowding
Visual acuity
- Driving score
- Perfect score
Visual acuity
- Driving score
- 0.3 LogMAR
- 6/ Snellen - Perfect score
- 6/6
- 0.0
Visual acuity
- Preferential looking based tests
Visual acuity
Preferential looking based tests
- Keeler preferential looking cards
- Cardiff acuity cards
- Kay’s pictures
- 2-4 yo - LogMAR Keeler book
- 4+ yo
- letter based
Testing low vision
Testing low vision
- Counting fingers (CF)
- Hand movements (HM)
- Perception of light (PL)
- No perception of light (NPL)
Cover test
- Additional observations
Cover test
- Additional observations
- Compensatory head posture
- Lid aperture
- Ptsosis
- Pupils
Cover test
Cover test
- Pen torch for reflections
- Fix on 3m target
- non accommodation - Occlude eye
Strabismus
- measuring deviation size
Strabismus
- measuring deviation size
- Prism cover test
Ocular motility test
- Grading
Ocular motility test
- Grading
1,2,3,4
- 4 if not moving past midline
Visual development
- Fovea
- Visual cortex
Visual development
4-6 mo
- fovea development
7-9yo
- visual cortex plasticity ends
Amblyopia
- Definition
- Consequence
Amblyopia
- Definition - ‘lazy eye’
- Reduction in vision in one eye
- absence of any structural abnormality or ocular disease - Cortical adaption
- abnormal binocular environment
- In adulthood can lead to functional blindness
Amblyopia and strabismus
- mx
Amblyopia and strabismus
- mx
- Refractive adaption to prescription
-18-20 weeks - Patching
- sight based dosing - Surgery
-can reccur
Types of diplopia
Types of diplopia
- Monocular double vision
- ghosting/blurry overlapping - Horizonal binocular
- Vertical binocular
- Oblique binocular
Occulomotor Nerve
- Branches
Occulomotor Nerve
- Branches
- Superior
1. LPS
2. Superior rectus - Inferior
1. MR. IR. IO
2. Cilliary ganglion
CN III Palsy
Mx
CN III Palsy
Mx
- Microvascular
- underlying issue eg. DM
- 6-9 mo recovery - …
CN IV Palsy
- Causes
CN IV Palsy
- Causes
1. RTC
2. Horse riding
3. Fall from height
- Congenital
- Lax SO tendon
- NB childhood head tilt
CN IV Palsy
- Pres
CN IV Palsy
- Pres
- Hypertropia
- CHP head tilt w/chin depression
- Vertical diplopia
- Torsion
CN VI Palsy
- Pres
-Causes
CN VI Palsy
- Pres
1. Esodeviation - especially distance
2. CHP - face turned
3. Horizontal diplopia
4. Limited abduction
-Causes
1. Microvascular
2. ICP
3. Trauma
Thyroid eye disease
- Mx
Thyroid eye disease
- Mx
- Euthyroid status
- Radio
- Medical anti-thyroid
- Thyroidectomy - Synthetic thyroid hormones
Graves’ orbitopathy
- Pattern of myopathy
Graves’ orbitopathy
- Pattern of myopathy
- IR
- MR
Others
Ocular myasthenia gravis
- pattern
Ocular myasthenia gravis (OMG)
- Pattern
1. Precedes generalised MG
2. Mimics any palsy
Myasthenia gravis
- ix
Myasthenia gravis
- Ix
- Orthoptic
- Sustained up gaze
- Cogans lid switch
- saccades
- peek test
- ice pack test - General
- AChR
- MuSK
- Electrodiagnostics
Myasthenia gravis
Mx
Myasthenia gravis
Mx
- Anti cholinesterase
- Pyridostigmine - Immunosuppression
Orbital tumours
Orbital tumours
- Optic nerve glioma
- Schwannoma
- Sarcoma
Eye muscle surgeries
Eye muscle surgeries
- Resection
- Strengthen action - Recession
- Weaken action
Age-related Macular Degeneration
- Stages
Age-related Macular Degeneration
- Stages
- Early AMD
- Intermediate AMD
- Advanced Dry AMD
- Advanced Wet AMD
Early AMD
- Features
Early AMD
- Features
- Medium-sized drusen
- Pigmentary abnormalities
Intermediate AMD
-Features
Intermediate AMD
-Features
- > 1 Large druse/numerous medium drusen
- Geography atrophy
- not extending to maular centre
Advanced Dry AMD
-Features
Advanced Dry AMD
-Features
- Non-exudative atrophic
- Drusen and GA extend to the macular centre
- Gradual vision loss
Advanced Wet AMD
-Featurest
Advanced Wet AMD
-Features
- Exudative/Neovascular
- Choroidal neovascularisation
- Rapid loss of vision
- Days/weeks
Macular degeneration
- Drusen
- Characteristics
- Types
Macular degeneration
- Drusen
- Characteristics
1. Yellow/white material
2. Between RPE and Bruch’s membrane - Types
1. Hard drussen - Small, hard, solid
- Soft drusen
- Larger soft deposits
AMD
- Progression
- Soft Drusen
- Pathology
AMD
- Progression
- Soft drusen lift RPE from Bruch’s membrane
- Hypoxia
- Inflammation
Dry AMD
- Cascade of Events
Dry AMD
- Cascade of Events
- Drusen
- Inflammation
- Monocytes/macrophages
- VEGF
- Neovascularisation
- Wet AMD
AMD
- RPE Hyper-hypopigmentation
AMD
- RPE Hyper-hypopigmentation
- Phagocytic and metabolic insufficency
- Post-mitotic RPE Cells - Accumulation of lipfuscin
- Age-pigment granules - Damage
- Proteins
- Lipids
- DNA
Dry AMD
- Epidemiology
- Early Features
- Advanced Features
Dry AMD
- Epidemiology
1. 80-90% of AMD - Early Features
- Initially no symptoms
- Drusen present
- Advanced features
3. Drusen then separate RPE from Bruch’s membrane
4. Confluent drusen
- Macular degeneration
- Gradual loss of VA
- Loss. of contrast sensitivity
- Abnormal dark progression
- Mild occasional metamorphosia - Geographic atrophy
- Significant visual loss
Dry AMD
- Features with high risk of progression
Dry AMD
- Features with high risk of progression
- Large drusen
- Reticular drusen
- Vitelliform lesions
- Atropy
- Scotomas
Dry AMD
- Mx
Dry AMD
- Mx
- Self monitor
- Amsler Grid (Metamorphosia) - Routine sight tests
- Community optometrist
Wet AMD
- Prognosis
Wet AMD
- Prognosis
- Rapid visual loss in 3 months
- Functional blindness in 2 years
- Untreated - Monocular disease risk of binocular disease
Wet AMD
- Pathology
Wet AMD
- Pathology
- VEGF stimulation
- through Bruch’s membrane - Fluid and blood leaks into retina
- Fibrous scar tissue
- Disciform
- Scotoma (blind spot) - Central vision loss
Wet AMD
- Anti-VEGF Agents
Wet AMD
- Anti-VEGF Agents
- Ranibizumab (Lucentis)
- Aflibercept (Eylea)
- Bevacizumab (Avastin)
- Brolucizumab) (Beovu)
Wet AMD
- Fundoscopy
Wet AMD
- Fundoscopy
- Oedema
- Elevation of retina
- Cystic oedema of sensory retina
Wet AMD
- OCT
Wet AMD
- OCT
- Fibrous scaring
- Sub-foveal atrophy/fibrosis
- Secondary to scar - Atrophy
- RPE
- Retina - Cystic degeneration
- Presence of fluid (dark space) below RPE
Wet AMD
- Visual acuity and treatment
Wet AMD
- Visual acuity and treatment
- VA ≤ 6/96
- If benefit expected
- Anti-VEGF tx for nAMD only - VA < 6/96
- Refraction prior to ARMD - VA > 6/12
- Anti-VEGF tx
Charles Bonnet Syndrome
- Features
- Epidemiology
Charles Bonnet Syndrome
- Features
1. People/animals
2. Light patterns - Epidemiology
1. 50% of ARMD
2. Usually aware they aren’t real
Eye exam
- Opthalmoscope
Eye exam
- Opthalmoscope
- Stabilise
- 15°
- optic disc
- macula
Diabetic retinopathy
- R Staging
Diabetic retinopathy
- R Staging
R0
R1 Early disease
- Dot haemorrhage
R2 Moderate/advanced disease (Pre-proliferative)
- Blot haemorrhages
- Tortuous and beading vessel
- IRMA
R3 Proliferative
Maculopathy
- M Staging
MaculopathyStaging
M0
-
M1
- Oedema
- Exudates greater/equal to half disc space