Opthalmology Flashcards

1
Q

Uveitis
- Significance

A

Uvea significance

  1. Most vascular tissue in body
  2. Host of insults
    - Autoimmune
    - Infectious
  3. Relationship to retina
    - Supply
    - Inflammation
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2
Q

Uvea
- Structure

A

Uvea

  1. Iris
  2. Cilliary body
  3. Chorea
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3
Q

Cilliary body
- Functions
- Inflammation

A

Cilliary body
- Functions

  1. Aqueous humour production
  2. Lens control
  • Inflammation
    3. Ciclitis/ intermediate uveitis
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4
Q

Uveitis
- Causes

A

Uveitis causes

  1. Unknown
  2. Autoimmune
  3. Infectious
  4. Traumatic
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5
Q

Uveitis classifications

A

Uveitis classifications

  1. Anterior
    - Iritis
  2. Intermediate
    - Ciclitis
  3. Posterior
    - Choroiditis
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6
Q

Keratic precipitates
- Classes

A

Keratic precipitates
- Classes

  1. Granulomatous
  2. Non-granulomatous
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7
Q

Aqueous humour
- direction of currents

A

Aqueous humour
- direction of currents

  1. Convection to anterior
  2. Gravity to inferior
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8
Q

Anterior uveitis
- Symptoms

A

Anterior uveitis
- Symptoms

  1. Pain
    - dull, orbital
  2. Redness
  3. Vision
    - Blurred/reduces
  4. Flare
    - floating leukocytes
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9
Q

Anterior chamber
- how to detect cells

A

Anterior chamber
- Detecting cells

  1. Dark room
  2. Thin beam of light
    - Slit lamp
  3. Cells seen
    - Inflammatory exudate in aqueous
    - usually 99% water
  4. Beam seen (flare)
    - Proteins in aqueous
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10
Q

Anterior uveitis
- signs

A

Anterior uveitis

  1. Posterior Synechiae
  2. Circumcorneal congestion
  3. Keratic precipitates
  4. Hypopyon
    - Fibrin meniscus on lower iris
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11
Q

Intermediate uveitis
- Symptoms

A

Intermediate uveitis
- Symptoms

  1. Blurring of vision
  2. Floaters
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12
Q

Intermediate uveitis
- Signs

A

Intermediate uveitis
- Signs

  1. Cells in vitreous
  2. Snow balls
  3. Snow banking
  4. Sheathing of blood vessels
  5. Macular oedema
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13
Q

Macular oedema
Ix

A

Macular oedema ix

  1. OCT
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14
Q

Posterior uveitis
- Symptoms

A

Posterior uveitis
- Symptoms

  1. Blurring of vision
  2. Floaters
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15
Q

Posterior uveitis
- Signs

A

Posterior uveitis
- Signs

  1. Reduced acuity
  2. Light sensitivity
  3. Reduced colour vision
  4. Reduced vision in dark (nyctalopia)
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16
Q

CMV retinitis
- Significance

A

CMV retinitis
- Significance

  1. Immunosuppression
    - HIV
    - Transplant/chemo
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17
Q

Uveitis treatment
- Infectious Vs non infectious

A

Uveitis treatment
- Infectious Vs non infectious

  1. Treat both with steroid
    - Scarring and inflammation is most significant factor
  2. Treat with ABx first if infectious
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18
Q

Uveitis
- Ix

A

Uveitis
- Ix

  1. FBC U&E LFT
  2. Q Gold
    - TB
  3. Treponemal antibody
    - Syphilis
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19
Q

Anterior uveitis
- Tx

A

Anterior uveitis
- Tx

  1. Topical steroids
    - Subconjunctival steroids
  2. Cycloplegics
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20
Q

Steroid eye drops
- ADRs

A

Steroid eye drops
- ADRs

  1. Glaucoma
    - Gradual rise in pressure
    - Insidious
    - Irreversible
  2. Cataracts
    - Posteror sub-capsular
    - Breadcrumb appearance
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21
Q

Intermediate and posterior uveitis
- Tx

A

Intermediate and posterior uveitis
- Tx

  1. Periocular steroids
  2. Intravitreal steroid implants
    - Ozurdex
    +Adjuncts
  3. Pulse therapy
  4. Oral steroids
  5. Immunosuppression
    - Better ADRs than steroids
  6. Specific antimicrobial
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22
Q

Steroids
- Dangerous ADRs

A

Systemic steroids
- Dangerous ADRs

  1. Hyperglycaemia
  2. HTN
  3. Immunosuppression
  4. Osteoporosis
  5. Cushings
  6. Anxiety and irritability
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23
Q

Anterior Uveitis
- Complications

A

Anterior Uveitis
- Complications

  1. Posterior Synechiae
  2. Pupillary membrane
  3. Ocular hypertension
    - Glaucoma
  4. Hypotonia
  5. Cataract
  6. Cystoid macular oedema
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24
Q

Posterior uveitis
- Complications

A

Posterior uveitis
- Complications

  1. Retinal detachment
  2. Posterior Synechiae
  3. Scarring
  4. Glaucoma
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25
High ocular pressure in uveitis - Tx
High ocular pressure - Tx 1. Steroids - Take baseline level (can increase) - Priority is inflammation
26
Sympathetic opthalmitis - Pathology
Sympathetic opthalmitis 1. Trauma to eye 2. Antigens to uveal pigment - Inflammation in contralateral eye - Vitiligo patches - Deafness - Meningism
27
Bony orbit - Border names
Bony orbit borders 1. Medial wall 2. Lateral wall 3. Floor 4. Roof
28
Orbital foramina - and contents
Orbital foramina 1. Optic foramen - nerve 2. Superior orbital fissure - most vessels 3. Infra-orbital foramen - Infra-orbital nerve - Infra orbital artery 4. Supra orbital notch - supra orbital nerve 5, Lacrimal groove - Naso-lacrimal duct 6. Lacrimal gland fossa - Lacrimal gland
29
Orbital bones
Orbital bones 1. Roof - frontal 2. Lateral wall - zygomatic - sphenoid 3. Medial - lesser sphenoid - ethemoid - Lacrimal bone - nasal process of maxilla 4. Floor - maxilla
30
Nasal duct - Opening
Nasal duct opening - Below inferior meatus
31
Orbital compartment syndrome
Orbital compartment syndrome - Retrobulbar haemorrhage 1. Proptosis 2. Pain 3. Blindness 4. Ophthalmoplegia 5. Miosis
32
Orbital septum - Continuous with...
Orbital septum - Continuous with periosteum of orbit
33
Horner's syndrome - Muscle
Horner's syndrome - Muscle Superior tarsal muscle
34
Blowout fracture - Symptoms
Blowout fracture - Symptoms 1. Pain 2. Numbness to cheek, upper lip and gum - Infra-orbital nerve
35
Blowout fracture - Pathology
Blowout fracture 1. Eye breaks bones - medial - inferior 2. Infra-orbital nerve damage
36
Stye Vs Chalazion (meimobian cyst)
Stye Vs Chalazion (meimobian cyst) 1. Sebaceous 2. Meimobian
37
Orbital Growths - inside Vs Outside cone
Orbital Growths - inside Vs Outside cone 1. Axial proptosis 2. Non-axial proptosis
38
Proptosis and lid-retraction - Cause
Proptosis and lid-retraction - Cause 1. Thyroid eye disease 2. Effects the muscles
39
Superior rectus and levator - share...
Superior rectus and levator - share... Tendon sheath
40
Ocular muscles - insertion
Ocular muscles - insertion 1. Rectus in front of axis 2. Oblique behind axis
41
Sixth nerve palsy - Anatomy
Sixth nerve palsy - Anatomy 1. Small nerve 2. Passes over the clivus - Easily compressed
42
Black on the eye
Black on the eye - Choroid
43
Slit lamp - 3D viewing
Slit lamp - 3D viewing 1. View straight ahead 2. Light beam at an angle
44
Fundus - Blind spot area - No vessels area
Fundus 1. Optic nerve - Blind spot area 2. Fovea - No vessels area
45
Eye symptoms
Eye symptoms 1. Foreign body sensation 2. Photophobia 3. Eye Pain 4. Headache 5. Lid irritation
46
Foreign body - How to evert
Evert an eye 1. Look down 2. Cotton bud 3. Pull up and over
47
Eye symptom - Foreign body sensation
Eye symptom - Foreign body sensation 1. Foreign body 2. Corneal abrasion
48
Eye symptoms - Photophobia ddx
Photophobia 1. Meningitis 2. Iritis 3. Migraine
49
Photophobia vs light sensitivity
Photophobia vs light sensitivity - Discomfort -> Photophobia
50
Eye pain - DDX
Eye pain ddx 0. Acute angle glaucoma 1. Trauma 2. Orbital cellulitis 3. Scleritis 4. Optic neuritis 5. Corneal abrasion
51
Ophthalmology - Headaches ddx
Ophthalmology - Headaches ddx 1. Migraine 2. Cluster headache - Eye watering 3. Trigeminal neuralgia 4. ICP - VI palsy - Bilateral optic disc swelling (papilloedema) - Postural change - Presence on waking - Pulsatile tinnitus 5. GCA - Temporal and tender - Jaw claudication - Scalp tenderness - Eye exam and markers
52
Lid irritation Ddx
Lid irritation Ddx 1. Stye - Follicle/seb gland - Edge of eyelid and sore - Fusillic acid ointment 2. Chalazion - Meim gland - Anywhere and painless - Warm compress 3. Blepharitis 4. Meimobian gland disease 5. Eczema/skin conditions
53
Conjunctivitis - causes and features
Conjunctivitis - Allergic 1. Bilateral 2. Trigger linked 3. Itchy - Viral 1. Often bilateral 2. Coryzal symptoms 3. Watery discharge - Bacterial 1. Generally unilateral 2. Purulent discharge
54
Visual disturbances - Generalised blurring ddx
Visual disturbances - Generalised blurring ddx 1. Refractive errors 2. Cataracts 3. Medications - steroids - tetracycline 4. Hormonal - pregnancy - period
55
Ophthalmology - Central blurring ddx
Ophthalmology - Central blurring ddx 1. Macular diseases - Age related - Diabetic T2 2. Drugs - Ethambutol - Hydroxychloroquine - Tamoxifen (deposits)
56
Ophthalmology - Black spots, blobs, and curtains
Ophthalmology - Black spots, blobs, and curtains 1. Vitreous 2. Retina traction and detachment - Flashing (immediate or ongoing) 3. TIA - Transient!
57
Retina tear pathology
Retina tear pathology 1. Vitreous traction 2. Retina hole 3. Vitreous behind retina 4. Retina detachment
58
Double vision - DDx
Double vision -DDx 1. Binocular - NMJ - Thyroid 2. Monocular - In eye - Chalazion/stye/abrasion - Detachment - Vitreous 3. Vertical or horizontal? - Nerves involved - Muscles involved? (Thyroid)
59
Ophthalmology - Colour changes ddx
Ophthalmology - Colour changes ddx 1. Optic nerve disease 2. Unilateral cataract 3. Red desaturation (unilateral) - Optic neuritis
60
Ophthalmology - Co-morbidities
Ophthalmology - Co-morbidities 1. Diabetes - Retina, CN palsy, ifct, vascular occlusion 2. HTN 3. Thyroid - retraction, lag, dry eye, neuropathy, motility 4. Ankylosing s - Iritis - Steroid SEs 5. Arthritis - RA, PA
61
Opthalmology Ix
Opthalmology Ix 1. Field test 2. OCT 3. Blood
62
Visual tests
Visual tests 1. Snellen 2. Near visual acuity test 3. Amsler grid 4. Ishihara colour grid
63
Visual tests - glasses
Visual tests - glasses 1. Best corrected vision 2. Distance glasses/reading glasses
64
Testing eyes - binocular/monocular
Testing eyes - binocular/monocular 1. Each eye - Eye occluder 2. AND both eyes
65
Recording vision - numerator and denominator
Recording vision 1. Numerator is distance 2. Denominator is reading
66
Eye test - Escalating tests
Eye test - Failing tests 1. 6m, pinhole, 3m, 1m 2. Fingers 3. Hand movements - let me know when it stops 4. Light projection - Top/bottom - Left/right 5. Light perception - say yes when you see the light shining
67
Pupil exam - 5 Stages
Pupil exam - 5 Stages STAND TO SIDE 1. Inspection 2. Direct light 3. Indirect light - Consensual 4. Swinging lights 5. Accommodation
68
Pupil abnormalities
Pupil abnormalities 1. Drugs - Opiates - Drops 2. Horner's 3. III
69
Swinging light test 1. Pathology 2. Method
Swinging light test 1. Pathology (Afferent pathway) Comparative defect L Vs R - Retina - Nerve 2. Method - Swing over bridge of nose - 1,2,3 seconds
70
Visual field confrontation - Peripheral method
Visual field confrontation - Peripheral method 1. Arm's length 2. Cover one eye - examiner same corresponding 3. How many fingers 4. Keep looking at eye - count fingers in field 5. Can you see pin? - keep looking at my eye 6. Keep your hand. - I will swap hands to use other hand
71
Visual field confrontation - Central vision
Visual field confrontation - Central vision 1. Red pin 2. Cover eye 3. Start at centre 4. Move very slowly 5. Acknowledge blind spot 6. Acknowledge return of pin
72
Fundoscopy - Use
Fundoscopy - Use 1. Green on button 2. Check position - examine at 0 3. Use diffuse beam in dark Or smallest beam 4. Approach patient from the side 5. Can I rest my hand on your forehead 6. Quick red reflex 7. Very close to eye - follow blood vessels - reach optic disc
73
Glaucoma - Definition
Glaucoma - Definition 1. Group of conditions 2. Progressive optic neuropathy 3. Optic nerve damage 4. Visual field defects 5. With/without pressure changes
74
Glaucoma - Definition
Glaucoma - Definition 1. Group of conditions 2. Progressive optic neuropathy 3. Optic nerve damage 4. Visual field defects 5. With/without pressure changes
75
Glaucoma - World significance
Glaucoma - World significance 1. Lead cause of Irreversible blindness
76
Glaucoma - World significance
Glaucoma - World significance 1. Lead cause of Irreversible blindness
77
Glaucoma - World significance
Glaucoma - World significance 1. Lead cause of Irreversible blindness
78
Glaucoma - World significance
Glaucoma - World significance 1. Lead cause of Irreversible blindness
79
Glaucoma - progression
Glaucoma - progression 1. Nasal step/temporal wedge 2. Arcuate 3. Tunnel vision 4. Complete field loss
80
Glaucoma - presentation
Glaucoma - presentation 1. Bumping things 2. Tripping and falling
81
Glaucoma DDx
Glaucoma DDx 1. GCA 2. Anterior ischemic optic neuropathy
82
Glaucoma - Pathophysiology
Glaucoma - Pathophysiology 1. Blockage of aqueous drainage 2. Poor blood supply to optic nerve
83
Aqueous humour - Function
Aqueous humour - Function 1. Nutrients to cornea 2. Waste from cornea
84
Glaucoma - Disc signs
Glaucoma - Disc signs 1. Cup to disc ratio increase 2. Bayonetting of blood vessels
85
Glaucoma - Types
Glaucoma - Types 1. Acute angle closure - primary or secondary - PAGG 2. Open angle glaucoma - primary/secondary - POAG - NTG, PXF, PG 3. Developmental glaucoma - congenital - reiters 4. Secondary - traumatic - uveitic - steroid
86
Open angle glaucoma RFs
Open angle glaucoma RFs 1. IOP 2. Age 3. African descent 4. FHx 5. Myopia
87
Angle closure glaucoma RFs
Angle closure glaucoma RFs 1. Raised IOP 2. Age 3. Far East/Inuits 4. Family history 5. Hyperopia
88
Glaucoma - Tx principle
Glaucoma -Tx principle 1. Increase outflow 2. Reduce inflow
89
IOP - Normal range
IOP - Normal range 1. Caucasian - 10-21mmHg (mean 16) 2. Black - Higher - greater Central Corneal Thickness
90
IOP - Measurement
IOP - Measurement 1. Goldmannn Mires - inside of rings just touch
91
IOP - Reduction measures
IOP - Reduction measures 1. Laser - Trabeculoplasty - Cyclodiode 2. Drops - Prostaglandins analogue - Beta blockers - Carbonic anhydrase inhibitors - Alpha 2 antagonists 3. Surgery - Trabeculectomy (Enophthalmitis risk lifelong) - Bleb
92
Acute closed angle glaucoma - Ss
Acute closed angle glaucoma Sx Red eye Pain Blue tinged cornea
93
Acute closed angle glaucoma - Mx
Acute closed angle glaucoma - Mx 1. Stat IV Acetazolamide 2. Laser peripheral iridotomy
94
Glaucoma medication - ADRs
Glaucoma medication - ADRs 1. Red eyes
95
Poor vision - Three questions
Poor vision - Three questions 1. Onset and consistency 2. Distance 3. Glasses? Recent eye test?
96
Optic refection 1. Cornea 2. Lens 3. Axial length
Optic refection 1. Cornea - 40 dioptres 2. Lens - 20 dioptres 3. Axial length - 23mm
97
Accommodation reflex - effect
Accommodation reflex - effect 1. Near distance light - not parallel like distant light 2. Lens changes to refract light
98
Refractive errors 3 types
Refractive errors 3 types 1. Anomalous axial length - long or short sighted - most common 2. Anomalous corneal power - eg after corneal graft/transplant 3. Physiological? Pathological?
99
Refractive errors - Myopia 1. Sight 2. Pathology 3. Management
Myopia 1. Sight - Short sighted 2. Pathophysiology - Long axial length (or high power cornea) 3. Management - Concave lenses
100
Refractive errors - Hypermetropia 1. Sight 2. Pathology 3. Management
Refractive errors - Hypermetropia 1. Sight - Long- sighted 2. Pathology - Short axial length Or low powered cornea 3. Management - Corrected with convex lens
101
Refractive errors - Astigmatism 1. Sight 2. Pathology 3. Management
Refractive errors - Astigmatism 1. Sight - Two foci - Blurred vision 2. Pathology - Two axes of curvature - Two foci 3. Management - Spectacle undercorrection - Spectacle over correction - Refractive surgery
102
Presbyopia - Pathology - Mx
Presbyopia - Pathology 1. Old eye 2. Declining amplitude of accommodation - Mx 1. Reading glasses 2. Bifocals/varifocals
103
Logarithmic chart - use
Logarithmic chart - use 1. Precise for treatments requiring a measure Eg. Macular degeneration
104
Assessment of refraction - examination
Assessment of refraction - Retinoscope (Automated or manual)
105
Refraction in children 1 Squint DDx 2 Assessment 3 Mx
Refraction in children 1. Squint - Hypermetropia? 2. Assessment - Retinoscopy under cycoplegia 3. Occlusion - Patch to make squinting eye develop - Diary for balancing eyes - Glasses for Hypermetropia
106
Diabetic retinopathy - RFs
Diabetic retinopathy - RFs 1. Duration of disease 2. Glycemic control 3. HTN 4. Nephropathy 5.Pregnancy 6. Obesity 7. Smoking
107
Diabetic retinopathy - Pathogenesis
Diabetic retinopathy - Pathogenesis 1. Occlusion & Ischaemia 2.IRMA - intra retinal microvascular abnormalities 3. Cotton wool spots 4. Irregular retinal veins - venous beading 5. Lipid collection 6. Oedema
108
Diabetic retinopathy - Leakage vs Occlusion
Diabetic retinopathy - Leakage vs Occlusion - Leakage 1. Loss of pericytes - Occlusion 1. BM thickening 2. Endothelial damage 3. RBC changes & rouleaux 4. Platelet aggregation
109
Diabetic retinopathy stages
Diabetic retinopathy stages 1. Background 2. Pre proliferative 3. Proliferative
110
Background Diabetic Retinopathy - Features - Management
Background diabetic retinopathy - Features 1. Micro aneurysm 2. Dot and blot haemorrhages 3. Hard exudate 4. Cotton wool spots Management - Observation
111
Diabetic retinopathy - Pre-proliferative features - Management
Diabetic retinopathy - Pre-proliferative features 1.IRMA - Intra-retinal microvascular abnormalities 2. Venous loops 3. Venous beading 4. Clusters of large blot haemorrhages 5. Multiple CW Spots Management - FU 4/12
112
Diabetic retinopathy - Proliferative phase Criteria
Diabetic retinopathy - Proliferative phase 1. NVD - Neo-Vascularisation of the Disc 2. >1/3 of NVD - or any vitreous haemorrhage 3. NVE (neo-vasc elsewhere) - >1/2 disk area - with vitreous or pre-retinal haemorrhage
113
Proliferative Diabetic retinopathy - Treatment
Proliferative Diabetic retinopathy - Treatment 1. Pan-Retinal-Photocoagulation (PRP) 2. Within 2 weeks
114
Diabetic maculopathy - Six classifications
Diabetic maculopathoes 1. Focal 2. Diffuse 3. Ischemic 4. Mixed 5. CSMO - Clinically significant macular oedema 6. Centrally involving
115
Diabetic maculopathy - Focal 1. Features 2. Treatment
Diabetic maculopathy Focal - Features 1 Well circumscribed areas of leakage 2 Oedema 3 Full/part rings of exudates - surrounding micro aneurysm - Treatment 1 Focal laser
116
Diabetic maculopathy - Diffuse 1. Features 2. Treatment
Diabetic maculopathy Diffuse - Features 1. Diffuse retinal thickness 2. Cystoid oedema 3. MA - Treatment 1. Grid laser
117
Diabetic maculopathy -Ischaemic 1. Features 2. Treatment
Diabetic maculopathy Ischemic - Features 1. Reduced VA 2. Normal clinically 3. Macular ischemia on FFA - Management 1. Observe
118
Clinically significant macular oedema - Definition - Mx
Clinically significant macular oedema - Definition 1. retinal thickening 2. within 500 microns of fovea Mx 1. Anti VEGF injections 2. Intra vitreal steroid implants
119
Diabetes - ocular complications
Diabetes - ocular complications 1. Retinopathy 2. Iridopathy 3. Unstable refraction 4. Orbital infection 5. Ocular ischaemic syndrome 6. Recurrent stye
120
Retinopathy treatment 1. Background 2. Pre-proliferative 3. Proliferative - Active - Stable - DMO
Retinopathy treatment 1. Background - 9-12/12 hospital FU 2. Pre-proliferative - 4-6/12 FU 3. Proliferative - Active ( PPR i 2/52) - Stable 4-6/12 FU - DMO (Macular laser and PRP +- anti VEGF +- steroid implants)
121
Vitreous haemorrhage 1 sx 2. Mx
Vitreous haemorrhage 1 sx 2. Mx - PRP same day for 2/52 - Vitrectomy +endolaser + anti VEGF if persistent
122
Rubeosis Sx Tx
Rubeosis Sx Tx
123
Pupil reflexes 1. APD 2. RAPD
Pupil reflexes 1. APD - Afferent pupillary defect 2. RAPD - Relative afferent pupillary defect - Swinging light reflex test
124
Afferent pupillary defects - Causes
Afferent pupillary defects - Causes 1. Optic neuritis 2. Demyelination 3. Trauma 4. Tumours 5. Retinal abnormality 6. Retinal detachment 7. Glaucoma 8. Artery/vein occlusion
125
3rd nerve palsy - Presentation
3rd nerve palsy - Presentation 1. Binocular diplopia 2. Anisocoria 3. Ptosis 4. Compensation - Abnormal head posture - Turn to one side
126
CN III Palsy - Differentials
CN III Palsy - Differentials 1. Microvascular - DM - HTN 2. Trauma 3. SoL 4. Aneurysm (PCom.Art.) 5. ICP 6. Horner's 7. Myasthenia gravis 8. Thyroid eye 9. Inter-nuclear ophthalmoplegia
127
Papilledema 1. S&S 2. DDx
Papilledema - S&S 1. Headaches - Worse on leaning forward 2. N&V 3. Visual changes and defects - DDx 1. SoL 2. Trauma 3. Haemorrhage 4. IIH - High BMI - COCP - Tetracycline 5. Venous sinus thrombosis - Perform MR venogram
128
Optic neuritis - S&S - Ix - Tx
Optic neuritis - S&S 0. Pain on eye movements 1. RAPD 2. Poor colour vision 3. Large blind spot - Ix 1. MRI - Tx 1. Steroids
129
Pediatric visual tests - Charts
Pediatric visual tests - Charts 1. Sheridan Gardner Test - Picture cards 2. Age-dependent 3. Observation - Fixing on objects - Following objects 4. Refractive errors - Cycloplegia
130
Red Reflex - Ix - DDx
Red Reflex - Ix 1. Opthalmoscope - Direct/indirect white reflex - DDx 1. Cataracts - TORCH - Galacktokinase - DM 2. Coats disease - Telangiectic neo-vascular disease 3. Retinoblastoma 4. RoP 5. Retinal detachment
131
Squint/Strabismus 1. Types 2. Complications
Squint/Strabismus - Types 0. Pseudo-squint 1. In-turn-esotropia 2. Out-turn-exotropia 3. Hypo/hypertropia - Complications 1. Amblyopia 2. Refractive error
132
Squint - Examinations
Squint - Examinations 1. Cover test - Cover one eye 2. Cover-uncover test - Quickly moving - For latent squint (when shut)
133
Strabismus - DDx
Strabismus - DDx 1. Coloboma (keyhole pupil) - Failure of optic fissure to close - Nystagmus and squints 2. Ptosis 3. Horner's syndrome - Neuroblastoma - Syringomyelia - Pheochromocytoma
134
Epiphora - Pathology - Mx
Epiphora - Pathology 1. Nasolacrimal duct non-canalisation 2. Watery eye - Mx 1. Self-resolving in first year 2. Reassure and massage 3. Syringe and probe
135
LogMAR Chart - Scoring - Advantages
LogMAR Chart - Scoring 1. 0.1 per line 2. 0.02 per letter - Advantages 1. Uniform reduction in size 2. Reduced letter crowding
136
Visual acuity 1. Driving score 2. Perfect score
Visual acuity 1. Driving score - 0.3 LogMAR - 6/ Snellen 2. Perfect score - 6/6 - 0.0
137
Visual acuity - Preferential looking based tests
Visual acuity Preferential looking based tests 1. Keeler preferential looking cards 2. Cardiff acuity cards 3. Kay's pictures - 2-4 yo 4. LogMAR Keeler book - 4+ yo - letter based
138
Testing low vision
Testing low vision 1. Counting fingers (CF) 2. Hand movements (HM) 3. Perception of light (PL) 4. No perception of light (NPL)
139
Cover test - Additional observations
Cover test - Additional observations 1. Compensatory head posture 2. Lid aperture 3. Ptsosis 4. Pupils
140
Cover test
Cover test 1. Pen torch for reflections 2. Fix on 3m target - non accommodation 3. Occlude eye
141
Strabismus - measuring deviation size
Strabismus - measuring deviation size 1. Prism cover test
142
Ocular motility test - Grading
Ocular motility test - Grading 1,2,3,4 - 4 if not moving past midline
143
Visual development - Fovea - Visual cortex
Visual development 4-6 mo - fovea development 7-9yo - visual cortex plasticity ends
144
Amblyopia - Definition - Consequence
Amblyopia - Definition - 'lazy eye' 1. Reduction in vision in one eye - absence of any structural abnormality or ocular disease 2. Cortical adaption - abnormal binocular environment - In adulthood can lead to functional blindness
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Amblyopia and strabismus - mx
Amblyopia and strabismus - mx 1. Refractive adaption to prescription -18-20 weeks 2. Patching - sight based dosing 3. Surgery -can reccur
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Types of diplopia
Types of diplopia 1. Monocular double vision - ghosting/blurry overlapping 2. Horizonal binocular 3. Vertical binocular 4. Oblique binocular
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Occulomotor Nerve - Branches
Occulomotor Nerve - Branches - Superior 1. LPS 2. Superior rectus - Inferior 1. MR. IR. IO 2. Cilliary ganglion
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CN III Palsy Mx
CN III Palsy Mx 1. Microvascular - underlying issue eg. DM - 6-9 mo recovery 2. ...
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CN IV Palsy - Causes
CN IV Palsy - Causes 1. RTC 2. Horse riding 3. Fall from height 4. Congenital - Lax SO tendon - NB childhood head tilt
150
CN IV Palsy - Pres
CN IV Palsy - Pres 1. Hypertropia 2. CHP head tilt w/chin depression 3. Vertical diplopia 4. Torsion
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CN VI Palsy - Pres -Causes
CN VI Palsy - Pres 1. Esodeviation - especially distance 2. CHP - face turned 3. Horizontal diplopia 4. Limited abduction -Causes 1. Microvascular 2. ICP 3. Trauma
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Thyroid eye disease - Mx
Thyroid eye disease - Mx 1. Euthyroid status - Radio - Medical anti-thyroid - Thyroidectomy 2. Synthetic thyroid hormones
153
Graves' orbitopathy - Pattern of myopathy
Graves' orbitopathy - Pattern of myopathy 1. IR 2. MR Others
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Ocular myasthenia gravis - pattern
Ocular myasthenia gravis (OMG) - Pattern 1. Precedes generalised MG 2. Mimics any palsy
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Myasthenia gravis - ix
Myasthenia gravis - Ix 1. Orthoptic - Sustained up gaze - Cogans lid switch - saccades - peek test - ice pack test 2. General - AChR - MuSK - Electrodiagnostics
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Myasthenia gravis Mx
Myasthenia gravis Mx 1. Anti cholinesterase - Pyridostigmine 2. Immunosuppression
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Orbital tumours
Orbital tumours 1. Optic nerve glioma 2. Schwannoma 3. Sarcoma
158
Eye muscle surgeries
Eye muscle surgeries 1. Resection - Strengthen action 2. Recession - Weaken action
159
Age-related Macular Degeneration - Stages
Age-related Macular Degeneration - Stages 1. Early AMD 2. Intermediate AMD 3. Advanced Dry AMD 4. Advanced Wet AMD
160
Early AMD - Features
Early AMD - Features 1. Medium-sized drusen 2. Pigmentary abnormalities
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Intermediate AMD -Features
Intermediate AMD -Features 1. >1 Large druse/numerous medium drusen 2. Geography atrophy - not extending to maular centre
162
Advanced Dry AMD -Features
Advanced Dry AMD -Features 1. Non-exudative atrophic 2. Drusen and GA extend to the macular centre 3. Gradual vision loss
163
Advanced Wet AMD -Featurest
Advanced Wet AMD -Features 1. Exudative/Neovascular 2. Choroidal neovascularisation 3. Rapid loss of vision - Days/weeks
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Macular degeneration - Drusen 1. Characteristics 2. Types
Macular degeneration - Drusen - Characteristics 1. Yellow/white material 2. Between RPE and Bruch's membrane - Types 1. Hard drussen - Small, hard, solid 2. Soft drusen - Larger soft deposits
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AMD - Progression 1. Soft Drusen 2. Pathology
AMD - Progression 1. Soft drusen lift RPE from Bruch's membrane 2. Hypoxia 3. Inflammation
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Dry AMD - Cascade of Events
Dry AMD - Cascade of Events 1. Drusen 2. Inflammation 3. Monocytes/macrophages 4. VEGF 5. Neovascularisation - Wet AMD
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AMD - RPE Hyper-hypopigmentation
AMD - RPE Hyper-hypopigmentation 1. Phagocytic and metabolic insufficency - Post-mitotic RPE Cells 2. Accumulation of lipfuscin - Age-pigment granules 3. Damage - Proteins - Lipids - DNA
168
Dry AMD - Epidemiology - Early Features - Advanced Features
Dry AMD - Epidemiology 1. 80-90% of AMD - Early Features 1. Initially no symptoms 2. Drusen present - Advanced features 3. Drusen then separate RPE from Bruch's membrane 4. Confluent drusen 5. Macular degeneration - Gradual loss of VA - Loss. of contrast sensitivity - Abnormal dark progression - Mild occasional metamorphosia 6. Geographic atrophy - Significant visual loss
169
Dry AMD - Features with high risk of progression
Dry AMD - Features with high risk of progression 1. Large drusen 2. Reticular drusen 3. Vitelliform lesions 4. Atropy 5. Scotomas
170
Dry AMD - Mx
Dry AMD - Mx 1. Self monitor - Amsler Grid (Metamorphosia) 2. Routine sight tests - Community optometrist
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Wet AMD - Prognosis
Wet AMD - Prognosis 1. Rapid visual loss in 3 months 2. Functional blindness in 2 years - Untreated 3. Monocular disease risk of binocular disease
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Wet AMD - Pathology
Wet AMD - Pathology 1. VEGF stimulation - through Bruch's membrane 2. Fluid and blood leaks into retina 3. Fibrous scar tissue - Disciform - Scotoma (blind spot) 4. Central vision loss
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Wet AMD - Anti-VEGF Agents
Wet AMD - Anti-VEGF Agents 1. Ranibizumab (Lucentis) 2. Aflibercept (Eylea) 3. Bevacizumab (Avastin) 4. Brolucizumab) (Beovu)
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Wet AMD - Fundoscopy
Wet AMD - Fundoscopy 1. Oedema 2. Elevation of retina 3. Cystic oedema of sensory retina
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Wet AMD - OCT
Wet AMD - OCT 1. Fibrous scaring 2. Sub-foveal atrophy/fibrosis - Secondary to scar 3. Atrophy - RPE - Retina 4. Cystic degeneration - Presence of fluid (dark space) below RPE
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Wet AMD - Visual acuity and treatment
Wet AMD - Visual acuity and treatment 1. VA ≤ 6/96 - If benefit expected - Anti-VEGF tx for nAMD only 2. VA < 6/96 - Refraction prior to ARMD 3. VA > 6/12 - Anti-VEGF tx
177
Charles Bonnet Syndrome - Features - Epidemiology
Charles Bonnet Syndrome - Features 1. People/animals 2. Light patterns - Epidemiology 1. 50% of ARMD 2. Usually aware they aren't real
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Eye exam - Opthalmoscope
Eye exam - Opthalmoscope 1. Stabilise 2. 15° - optic disc - macula
179
Diabetic retinopathy - R Staging
Diabetic retinopathy - R Staging R0 R1 Early disease - Dot haemorrhage R2 Moderate/advanced disease (Pre-proliferative) - Blot haemorrhages - Tortuous and beading vessel - IRMA R3 Proliferative
180
Maculopathy - M Staging
MaculopathyStaging M0 - M1 - Oedema - Exudates greater/equal to half disc space