Opportunistic Mycoses

Question 1

Fungal infections caused by saprophytes

Answer 1

Opportunistic Mycoses

Question 2

Characteristics of Opportunistic Fungi

Answer 2

Rapid growth - 25C - 30C
Poor growth - 35C - 37C
Abundant sporulation
Pigmented

Question 3

Agent for Farmer’s Lung Diseases and most common Lab contaminant

Answer 3

Aspergillus spp.

Question 4

Characteristics Aspergillus spp.

Answer 4

Septate Hyphae
Conidiophore is enlarged forming swollen vesicle
Vesicles are covered with FLASKED SHAPED PHIALIDES

Question 5

A. fumigatus

Answer 5

Diseases: Fungus Ball, Aspergilloma, Bread Mold
Macroscopic: White to Blue green Pigment
Microscopic: Unisiriate phialides (parallel)

Question 6

A. flavus

Answer 6

Diseases: Aflotoxicosis
Toxin: Aflotoxin

Macroscopic: yellow-green pigment

Microscopic:
Biseriate phialides
Brownish Sclerotia
Conidia are globose to sub-globose (pale green)

Question 7

A. niger

Answer 7

Disease: Fungus Ball
Macroscopic:
Surface - White - Yellow - Black
Reverse - White or Yellow

Microscopic:
Biseriate phialides
RADIATE HEAD

Question 8

A. versicolor

Answer 8

Toxin: Mycotoxin, Sterigmatocystin

Macroscopic:
Surface - Pale green - Dark green - Pinkish Green
Reverse - REDDISH

Microscopic:
Septate Hyphae, Hyaline
Biseriate, Loosely raidiate
Small Vesicles

Question 9

Main Diseases of Aspergillosis

Answer 9

Allergic Bronchopulmonary aspergillosis
Acute invasive aspergillosis
Disseminated Invasive aspergillosis

Question 10

Hypersensitivity to Aspergillus spores

Answer 10

Allergic Bronchopulmonary aspergillosis