Opioids Flashcards
When prescribing opioids on FP10 what must you do?
write in words and figures the total quantity required
Parental route is how many more time potent than IV in opioids
x2
Most modified release morphine tables are to be taken how many times a day?
twice
MXL morphine tables to be taken how many times a day ?
once day
Recommended starting doses for morphine
Opioid Naive -
Frail / elderly
Everyone else
5mg every 4hrs
2.5mg every 4 hours
10mg every 4 hours
How to calculate MR release dose
Total amount of opioid in 24hrs
/2 to get 12 hourly dose
Break through dose should be between
1/10 of total dose to 1/6
Max increase of opioid dose
more than 50%
Potency of x compared to oral morphine
Codeine
Tramadol
Oxycodone oral
Morphine IM/IV/SC
Oxycodone SC
- 1
- 1
- 5-2
2
3-4
How to calculate morphine to new opioid
divide by potency
how to calculate opioid to morphine
multiply by potency
Drugs to manage SE of opioids
Anti emetics e.g. cyclezine
Stimulant laxatives - senna prn
Doses of naloxon
400 micrograms
if that doesn’t work
800 micrograms up to two doses, 1 min intervals
