Opioid Toxicity Medical Directive Flashcards
Opioid Toxicity MD
What are the indications for the opioid toxicity MD?
Altered LOC;
AND
Respiratory depression;
AND
Inability to adequately ventilate OR persistent need to assist ventilations;
AND
Suspected opioid overdose.
Opioid Toxicity MD
What are the indications for the opioid toxicity MD?
Altered LOC;
AND
Respiratory depression;
AND
Inability to adequately ventilate OR persistent need to assist ventilations;
AND
Suspected opioid overdose.
Opioid Toxicity MD
What are the conditions for naloxone administration?
Age: ≥24 hours
LOA: Altered
RR: <10 breaths/min
Opioid Toxicity MD
What are the contraindications to naloxone administration?
Allergy or sensitivity to naloxone
Opioid Toxicity MD
What is the order of preference for naloxone administration?
IV/IM/IN/SC
Opioid Toxicity MD
What is the dose for naloxone IV?
Up to 0.4 mg, dosing interval 5 min, max 3 doses. (Titrate to restore respiratory status only)
Opioid Toxicity MD
What is the dose for naloxone IM?
0.4 mg, dosing interval 5 min, max 3 doses.
Opioid Toxicity MD
What is the dose for naloxone IN?
2-4 mg, dosing interval 5 min, max 3 doses. (Divide dose between nares)
Opioid Toxicity MD
What is the dose for naloxone SC?
0.8 mg, dosing interval 5 min, max 3 doses.
Opioid Toxicity MD
If the patient doesn’t respond to airway management and the administration of naloxone, what should be considered?
Glucometry.
Opioid Toxicity MD
Can we patch for more doses?
Yes.
Opioid Toxicity MD
What kind of behaviour should be anticipated after naloxone administration?
Combative behaviour should be anticipated following naloxone administration, and paramedics should protect themselves accordingly, thus the importance of gradual titrations (if given IV) to desired clinical effect: respiratory rate ≥10, adequate airway and ventilation, not full alertness.