Opioid Neuraxial

Question 1

BUPRENORPHINE
Neuraxial dosing

Answer 1

• Epidural: 0.3 mg
• Intrathecal: 0.15 mg

Question 2

MORPHINE
Adult Neuraxial dosing

Answer 2

Epidural

• Bolus 2-6 mg q8-24h
• Infusion 0.2-1 mg/hr

Intrathecal

• 0.1-0.5 mg

Question 3

MORPHINE
Peds Neuraxial dosing

Answer 3

Epidural

• 0.03-0.05 mg/kg
• MAX = 0.1 mg/kg or 5 mg/24h

Intrathecal

• 0.01 mg/kg

Question 4

FENTANYL
Neuraxial dosing

Answer 4

• Intrathecal: 10-25 mcg (Dr. C says 20 is a sweet spot)
• Epidural: 10-100 mcg