Opioid Analgesics and Responsible opioid prescribing

Question 1

Opiates vs Opioids vs Narcotics

Answer 1

Question 2

Opioid Receptors, Agonists (Pure, Partial & Mixed)

Answer 2

Question 3

Pharmacologic Effects of the Opioid Receptors

Answer 3

Mu2 causes the most response

Question 4

Opioids with Mixed Agonists-Antagonists

Answer 4

• “But Billy Needed MIXED Pills”
  
  • Butorphanol, Buprenorphine, Nalbuphine, Pentazocine
  • NEVER use partial agonists or mixed agonist-antagonists together with PURE AGONISTS

Question 5

Available Opiates/Opioids in US

Answer 5

Question 6

The Different Preparations of Opioids

Answer 6

Question 7

How to manage pain & select the correct opioid

Answer 7

Question 8

What to evaluate prior to starting opioids

Answer 8

Question 9

Summary of the Opioids Classification

Answer 9

Question 10

Clinical Uses of Opioids & SEs

Answer 10

Question 11

Pseudo-Allergy vs True Allergy

Answer 11

Question 12

How to Manage or Tx the SEs from Opioids

Answer 12

Question 13

Morphine

Answer 13

• Pure MU-agonist
• Available as: PO, IR, ER, Rectal Suppository, PO liquid, parenteral
• T½ = ⅔ hours (IR forms)
• Duration: 3-6 hours
• ER form duration: 8-24 hours

Question 14

Meperidine (Demerol)

Answer 14

Question 15

Methadone

Answer 15

Question 16

Tramadol

Answer 16

Question 17

Tapentadol (Nucynta)

Answer 17

Question 18

Fentanyl

Answer 18

Question 19

Oliceridine (Olinvyk)

Answer 19

Question 20

Combining Analgesics

Answer 20

Question 21

Opioid Usage & Precautions

Answer 21

Question 22

Opioid Effects vs Withdrawal

Answer 22

Question 23

Responsible Opioid Prescribing

Answer 23

Question 24

Opioid Risk Tool

Answer 24

Question 25

SOAPP vs COMM Opioid Risk Tools

Answer 25

insert slide

Question 26

Components of Treatment Agreement

Answer 26

Question 27

CDC Guidelines for Prescribing Opioids

Answer 27

Question 28

Cross-Reactivity between Opioids & True Allergies

Answer 28

Question 29

Opioid Equianalgesic Doses

Answer 29

Question 30

Opioid Tapering & Rotations

Answer 30