Opiods Flashcards

1
Q

Opiods Potency from greatest to least

SR FAD MD

A

Sufentanil > Remifentanil > Fentanyl > Alfentanil> Dilaudid > MSO4 > Demerol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Infusion rates range: sufentanil

A

0.0015 to 0.01 mcg/kg/min

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Infusion rates range: fentanyl

A

0.01 to 0.05 mcg/kg/min

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Infusion rates range: remifentanil

A

0.05 to 0.25 mcg/kg/min

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Infusion rates range: alfentanil

A

0.25 to 0.75 mcg/kg/min

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Drug Dosages Meperidine

A

50 to 100mg IV produces variable degrees of pain relief and is not always effective in patients with severe pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Drug Dosages Sufentanil

A

0.1-0.3 mcg/kg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Drug Dosages Remifentanil

A

1-2 mcg/kg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Drug Dosages Fentanyl

A

1-3 mcg/kg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Drug Dosages Alfentanil

A

10-20 mcg/kg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Opiods pK (Onset)/ % Unionized

A
Alfentanil 6.5 / 89%
Remifentanil 7.3 / 58%
Morphine 7.9 / 35%
Sufentanil 8.0 / 20%
fentanyl 8.4 / 8.5%
Meperidine 8.5 / 7 %
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Elimination 1/2 time

A
Remifentanil 0.17- 0.33
Alfentanil 1.4 - 1.5
Morphine 1.7- 3.3
Sufentanil 2.2- 4.6
Meperidine 3.5
fentanyl 3.1- 6.6
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Protein Binding (DOA)

A
Morphine 35%
Merepidine 70%
Fentanyl 84%
Alfentanil 92%
Sufentanil 93%
Remifentanil 66-93%
How well did you know this?
1
Not at all
2
3
4
5
Perfectly