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Anesthesia Pharmacology > ANS > Flashcards

ANS Flashcards

1
Q

Name the tissues on which a1 Receptors are found (Work)

Gq) (Inc. Ca

A 
Vascular smooth muscle
Iris (radial muscle)
Pilomotor smooth muscle
Prostate/uterus
Heart
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2
Q

a1 action on Vascular smooth muscle

A

Contraction

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3
Q

a1 action on Iris (radial muscle)

A

Contraction (dilates)

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4
Q

a1 action on Pilomotor smooth muscle

A

Erects hair

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5
Q

a1 action on Prostate/uterus

A

Contraction

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6
Q

a1 action on Heart

A

Increase force of contraction

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7
Q

Name the tissues on which a2 receptors are found
(Gi)
dec. cAMP, Inc. K conductance

A 
Platelets
Presynaptic
Smooth Muscle
GI Tract
CNS
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8
Q

a2 action on Platelets

A

Aggregation

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9
Q

a2 action on Presynaptic.. Adrenergic & nerve terminals

A

Inhibits NT release (dec. BP, dec. HR)

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10
Q

a2 action on Vascular Smooth Muscle

A

Contraction (post) Dilation (pre)

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11
Q

a2 action on GI Tract

A

Relaxation

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12
Q

a2 action on CNS

A

Sedation/analgesia via Inc. SNS flow from brainstem

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13
Q

Name the tissues on which B1
(Gs)
Inc. cAMP

A

Heart

Kidneys

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14
Q

B1 action on Heart

A

Inc. Contractility, Inc. HR

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15
Q

B1 action on Kidneys

A

Inc. Renin release

- Na/H2O absorption

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16
Q

Name the tissues on which B2
(Gs)
cAMP

A 
Respiratory, Uterine, Vascular, GI, GU 
(visceral smooth muscle)
Mast Cells
Skeletal Muscle
Liver
Pancreas
Adrenergic Nerve Terminals
17
Q

B2 action on Respiratory, Uterine, Vascular, GI, GU

visceral smooth muscle

A

Smooth muscle relaxation

18
Q

B2 action on Mast Cells

A

Dec. Histamine release

19
Q

B2 action on Skeletal Muscle

A

K+ uptake, tremor, Inc.

speed of contraction, Inc. BF, dilation vascular beds

20
Q

B2 action on Liver

A

Glycogenolysis- glucose

21
Q

B2 action on Pancreas

A

Inc. Insulin secretion

22
Q

B2 action on Adrenergic Nerve Terminals

A

Inc. release of NE

23
Q

Name the tissues on which D1

A

Smooth muscle

24
Q

D1 action on Smooth muscle

A

Post synaptic

- Dilates renal, mesenteric, coronary, cerebral blood vessels

25
Q

Name the tissues on which D2

A

Nerve endings

26
Q

D2 action on Nerve endings

A

Pre-synaptic

-Modulates transmitter release; N/V

Anesthesia Pharmacology (7 decks)

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