ANS Flashcards
Name the tissues on which a1 Receptors are found (Work)
Gq) (Inc. Ca
Vascular smooth muscle Iris (radial muscle) Pilomotor smooth muscle Prostate/uterus Heart
a1 action on Vascular smooth muscle
Contraction
a1 action on Iris (radial muscle)
Contraction (dilates)
a1 action on Pilomotor smooth muscle
Erects hair
a1 action on Prostate/uterus
Contraction
a1 action on Heart
Increase force of contraction
Name the tissues on which a2 receptors are found
(Gi)
dec. cAMP, Inc. K conductance
Platelets Presynaptic Smooth Muscle GI Tract CNS
a2 action on Platelets
Aggregation
a2 action on Presynaptic.. Adrenergic & nerve terminals
Inhibits NT release (dec. BP, dec. HR)
a2 action on Vascular Smooth Muscle
Contraction (post) Dilation (pre)
a2 action on GI Tract
Relaxation
a2 action on CNS
Sedation/analgesia via Inc. SNS flow from brainstem
Name the tissues on which B1
(Gs)
Inc. cAMP
Heart
Kidneys
B1 action on Heart
Inc. Contractility, Inc. HR
B1 action on Kidneys
Inc. Renin release
- Na/H2O absorption
Name the tissues on which B2
(Gs)
cAMP
Respiratory, Uterine, Vascular, GI, GU (visceral smooth muscle) Mast Cells Skeletal Muscle Liver Pancreas Adrenergic Nerve Terminals
B2 action on Respiratory, Uterine, Vascular, GI, GU
visceral smooth muscle
Smooth muscle relaxation
B2 action on Mast Cells
Dec. Histamine release
B2 action on Skeletal Muscle
K+ uptake, tremor, Inc.
speed of contraction, Inc. BF, dilation vascular beds
B2 action on Liver
Glycogenolysis- glucose
B2 action on Pancreas
Inc. Insulin secretion
B2 action on Adrenergic Nerve Terminals
Inc. release of NE
Name the tissues on which D1
Smooth muscle
D1 action on Smooth muscle
Post synaptic
- Dilates renal, mesenteric, coronary, cerebral blood vessels
Name the tissues on which D2
Nerve endings
D2 action on Nerve endings
Pre-synaptic
-Modulates transmitter release; N/V