Ophthalmology Flashcards

1
Q

Painless monocular visual loss that suddenly resolves with normal examination findings?

A

Amaurosis fugax (TIA)

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2
Q

What retinal changes are seen in diabetic retinopathy on ophthalmoscopy?

A

Bilateral hard exudates, bilateral cotton wool spots

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3
Q

What is acute closed-angle glaucoma?

A

A sudden increase in intra-ocular pressure (affecting one eye)

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4
Q

How does acute closed-angle glaucoma present?

A

1) Excruciating pain in the affected eye at rest
2) Nausea
3) Visual haloes
4) Blurred vision
5) Red eye with pupillary abnormalities

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5
Q

What does the eye look like in acute closed-angle glaucoma?

A

Red eye with pupillary abnormalities

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6
Q

What is anterior ischaemic optic neuritis?

A

1) Complication of giant cell/temporal arteritis
2) Involvement of the ophthalmic artery causes spasm, occlusion and subsequent irreversible ischaemia of the retina

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7
Q

Which ophthalmic condition is a complication of giant cell/temporal arteritis?

A

Anterior ischaemic optic neuritis

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8
Q

How does anterior ischaemic optic neuritis present?

A

1) Painless monocular visual loss - irreversible, doesn’t resolve like TIA
2) History of GCA symptoms (e.g. scalp tenderness, jaw claudication, weight loss)

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9
Q

What would ophthalmoscopy show in anterior ischaemic optic neuritis?

A

Chalky white and swollen optic disc

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10
Q

What is the difference between anterior ischaemic optic neuritis and amaurosis fugax?

A

Both have painless monocular visual loss but in anterior ischaemic optic neuritis this does not spontaneously resolve and is irreversible

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11
Q

Chalky white and swollen optic disc?

A

Anterior ischaemic optic neuritis

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12
Q

What are the two causes of vitreous haemorrhage?

A

1) Diabetic eye disease - causes abnormal blood vessels which bleed into the vitreous humour
2) Retinal tears - bleed into the vitreous

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13
Q

What is a vitreous haemorrhage?

A

Bleeding into the vitreous humour

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14
Q

What would you see in ophthalmoscopy of vitreous haemorrhage?

A

Ophthalmoscopy would not be possible in the affected eye in large bleeds, as the retina is obscured

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15
Q

How does vitreous haemorrhage present?

A

Blood in the eye/on ophthalmoscopy, visual loss that would not return spontaneously, signs of diabetic eye disease or retinal tears

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16
Q

What is retinal detachment?

A

When the sensory retina peels away from the underlying pigmented retinal epithelium

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17
Q

What can cause retinal detachment?

A

1) Tear in the retina allowing fluid behind the top layer
2) Tugging of the retina by fibrous tissue in the overlying vitreous humour

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18
Q

How does retinal detachment present?

A

1) Painless visual loss (irreversible but surgery can reduce the extent of damage)
2) History of preceding flashes of light - as the detaching retina tugs on the optic nerve
3) History of floaters - as blood and debris collect in the vitreous

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19
Q

Which part of the optic pathway is disrupted in monocular visual loss?

A

Optic nerve

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20
Q

Which two parts of the optic pathway can be disrupted in contralateral homonymous hemianopia i.e. nasal field of one eye and nasal field of the other eye?

A

1) Optic tract (running from the optic chiasm to the ipsilateral geniculate body of the thalamus)
2) Optic radiation (backward extension of the optic tract - from the lateral geniculate body of the thalamus to the ipsilateral primary visual cortex)

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21
Q

Which part of the optic pathway is disrupted in bitemporal hemianopia?

A

Optic chiasm (here the nasal fibres of each eye cross the midline to join the temporal fibres of the contralateral eye) e.g. pituitary tumour

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22
Q

Which fibres of the optic radiation pass through the temporal lobe?

A

The fibres that carry visual stimuli from the lower retina (which receives stimulation from the upper half of the visual fields)

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23
Q

Which fibres of the optic radiation pass through the parietal lobe?

A

The fibres that carry visual stimuli from the upper retina (which receives stimulation from the lower half of the visual fields)

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24
Q

A lesion in what location would cause a contralateral homonymous superior quadrantanopia?

A

Temporal lobe

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25
A lesion in what location would cause a contralateral homonymous inferior quadrantanopia?
Parietal lobe
26
A lesion in what cerebral location would cause a contralateral homonymous hemianopia with macular sparing?
Occipital lobe
27
Pathology in which locations would cause monocular visual loss?
Orbit, retina or optic nerve
28
How does preseptal cellulitis present?
1) Erythema and oedema around the eyelid of one eye 2) Normal visual acuity and eye movements 3) Background of cold
29
What is preseptal cellulitis?
Infection of the superficial tissues around the eyelid
30
How do you manage paediatric preseptal cellulitis?
1) Immediate empirical IV abx for 2-5 days OR 2) Empirical oral abx in children with reliable daily follow up
31
Why do you need to treat paediatric preseptal cellulitis immediately with empirical abx?
Bc of the risk of occult orbital cellulitis or rarely worsening to orbital cellulitis and its complications
32
What is a serious complication of orbital cellulitis and why?
Meningitis - the infection can track from the orbit into the CNS
33
How do you manage orbital cellulitis (deep infection)?
1) IV abx 2) IF not a rapid response to IV abx - urgent surgical decompression of the orbit
34
What is the leading cause of blindness in the UK?
Age related macular degeneration (ARMD)
35
How does age related macular degeneration present?
Subacute loss and/or distortion of the central visual field (central vision loss)
36
What causes age related macular degeneration?
Degeneration of photoreceptors in the central retina (macula)
37
What is visible on slit-lamp biomicroscopy/fundoscopy in age related macular degeneration?
Drusen in the macula
38
What condition are drusen indicative of?
Dry age related macular degeneration
39
What are the risk factors for age related macular degeneration?
1) Age (main risk factor) 2) Male sex 3) Smoking 4) FH 5) Cardiovascular risk factors
40
What is conjunctivitis?
Conjunctival inflammation
41
What is non-infectious cause of conjunctivitis?
Allergic
42
What are bacterial causes of conjunctivitis?
1) Staph aureus and epidermis 2) Strep pneumoniae 3) Haemophilus influenzae 4) Consider chlamydia/gonorrhoea
43
What is the most common viral cause of conjunctivitis?
Adenovirus
44
How does conjunctivitis present?
1) Red, painful eye 2) Gritty/itchy sensation 3) Discharge 4) ± photophobia
45
What is conjunctival discharge like in bacterial conjunctivitis?
Purulent
46
What is conjunctival discharge like in (neonatal) chlamydia conjunctivitis?
Mucopurulent
47
What is conjunctival discharge like in viral conjunctivitis?
Serous
48
What would the presence of photophobia in conjunctivitis suggest?
Corneal involvement - keratoconjunctivitis
49
How do you diagnose conjunctivitis?
Clinical
50
How do you manage bacterial conjunctivitis?
1) Conservative - self limiting, 1-2 weeks 2) Lubricating eye drops 3) Topical chloramphenicol - in severe infections
51
How do you manage viral conjunctivitis?
1) Conservative - self-limiting 2) Good eye hygiene to prevent spread to other eye 3) Artificial tears 4) Wash hands regularly and do NOT share towels - very contagious
52
What is the treatment for severe conjunctivitis?
Topical chloramphenicol (antibiotic)
53
What is keratitis/corneal ulcer?
Infection of the cornea - common sight-threatening ophthalmic emergency
54
What is the most common bacterial cause of keratitis?
Pseudomonas
55
Which patients are most susceptible to keratitis/corneal ulcer?
Contact lens users
56
What is the most common viral cause of keratitis?
Herpes simplex keratitis
57
How does keratitis present?
1) Painful, red eye 2) Foreign body sensation 3) Tearing (epiphora) 4) Purulent discharge 5) Corneal ulcer 6) Photophobia
58
What is the key symptom to differentiate between plain conjunctivitis and keratitis?
Photophobia
59
How do you diagnose keratitis?
1) Slit-lamp examination (with fluorescein staining) 2) Corneal scrape 3) Contact lens (± solution) sent for culture
60
What finding on slit lamp examination is pathognomonic for HSV keratitis?
Dendritic ulceration
61
What is the first line investigation in keratitis?
Slit-lamp examination (with fluorescein staining)
62
How do you manage bacterial keratitis?
1) Emergency referral to ophthalmology 2) Intensive topical/PO abx - chloramphenicol 3) Admission
63
How do you manage viral HSV keratitis?
Topical aciclovir