Ophthal misc Flashcards
Features of afferent defect and cause
No direct response, intact consensual response in other eye
No consensual response from initiation in contralateral eye
Total CN II lesion
Features of RAPD (marcus-gunn pupil) and causes
Minor constriction to direct light
Dilatation on moving light from normal to abnormal eye
optic neuritis
Optic atrophy
Retinal disease
Features of efferent defects and causes
Dilated pupil does not react to light
Consensual response intact in contralateral eye
3rd nerve palsy
Causes of a fixed dilated pupil
Mydiatrics e.g. tropicamide
Iris trauma
Acute glaucoma
CN III compression (surgical)
Features of Horner’s syndrome and causes
Ptosis
Mydriasis
Anhidrosis
Central (MS, Lateral Medullary Syndrome)
Pre-ganglionic (Pancoast tumour, CVA insertion)
Post-ganglionic (cavernous sinus thrombus, CN 3-6 palsy)
Features of a holmes-adie pupil and causes
Dilated pupil
- no response to light
- sluggish accommodation
Damaged post-ganglion fibres
Viral/bacterial infection of ANS
Features of an argyll-Robertson pupil and causes
Small, irregular pupil
Sluggish response to light
Accommodation intact
Damage to the ciliar ganglion:
DM
Syphilis (quaternary)
Features of Hutchinson’s pupil and causes
Unilaterally dilated pupil
Unresponsive to light
- [1] ipsilateral pupil constricts (PNS irritation)
- [2] ipsilateral pupil dilates (PNS inhibited)
- [3] contralateral pupil constricts (PNS irritation)
- [4] contralateral pupil dilates (poor prognosis)
Intracranial mass / raised ICP head trauma
Features fo optic atrophy
Reduced acuity
Reduced colour vision (esp. red)
Central scotoma
Pale optic disc
RAPD
Causes of optic atrophy
Congenital: HMSN/CMT, friedrich’s ataxia, reinitis, pigmentosa, LHON
Alcohol/toxins : EtOH, ethambutol, lead, B12
Compression: neoplasia, glaucoma, paget’s
vascular: DM, GCA, stroke
Inflammatory: MS
Sarcoidosis
Infection: VZV, TB< syhpilis
Neoplastic infiltration: leukaemia, lymphoma
Features of corneal abrasion clinically and on investigation
Epithelial breech without keratitis
S/S: pain, photophobia, blurred vision, visible defect
Ix: slit lamp fluorescein staining defect green
Management for corneal abrasion
infection prophylaxis (chloramphenicol ointment)
Features of ophthalmic shingles/herpes zoster ophthalmicus
CN V1 reactivation of VZV (10% of all shingles)
S/S: pain → blistering rash; 40% associated keratitis/uveitis
Hutchinson’s sign = nose-tip zoster (naso-ciliary branch) → ophthalmic involvement = keratitis ± corneal ulceration ± iritis
Management for Ophthalmic shingles / Herpes Zoster Opthalmicus
Fundoscopy, slit lamp fluorescein staining
referral → oral aciclovir (7-10 days) ± topical corticosteroids (if inflammation)
Complications of Ophthalmic shingles / Herpes Zoster Opthalmicus
Ptosis
Post-herpetic neuralgia
Ocular (conjunctivitis, keratitis, episcleritis, anterior uveitis)