OP - L2 Flashcards

1
Q

system definition

A

A group organs that are specialised to perform specific function within an organism

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2
Q

What is classification based on

A

Function

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3
Q

Homeostasis definition

A
  • It is a dynamic state of equilibrium
  • To maintain physiological constancy in a changing environment
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4
Q

How many organ systems in the body?

A

11

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5
Q

How many bones? ribs?

A

204
24 (12 front and back)

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6
Q

4 types of cells in the skeletal system and their function?

A

Osteoblasts - Make bone cells (deposition)
Osteoclasts- Secrete enzymes and acid (resorption)
Osteocytes - differentiated osteoblasts
Chondrocytes - cells in the bone that divide and enlarge in response to growth hormone

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7
Q

What does a lack and excess of growth hormone result in kids and adults?

A

Lack - dwarfism
Excess:
Adults - acromegaly
Childhood - gigantism

Growth hormone treatment doesnt work on adults

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8
Q

How long is the GIT?

A

4.5 m
Extends from mouth to rectum

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9
Q

what is the main function of kidneys?

A

To maintain/regulate the water levels in the blood

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10
Q

How are nutrients and oxygen transported in blood?

A

nutrients - in plasma
oxygen - RBCs

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11
Q

What do melatonin and insulin regulate?

A

Melatonin - biorhythms (circadian(sleep cycle))
Insulin - glucose levels

** Part of endocrine system - hormones secreted into blood

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12
Q

What is innate and adaptive immunity?

A

Innate - non-specific immunity (skin as a barrier, macrophages)
Adaptive - specific immunity (t-cell and b-cell response)

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13
Q

What is the largest organ system - its function and components? which immune system is it part of? what determines its colour?

A

Integumentary system
– Protective barrier, distinguishes/separates organism from its surroundings
– skin, hair, nails, skin glands+their products
– Innate immunity
– Level of Melanin determines colour

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14
Q

Major organ systems - their organs - their function

A
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15
Q

Tissue definition

A

A group of specialised cells grouped together to perform a specific function

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16
Q

4 types of tissue - which ones are excitable? give examples of each

A

EXCITABLE:
- Muscle [skeletal (attaches bones to tendons) , cardiac (in heart), smooth (vasculature, bronchioles, digestive tract, reproductive tract)]
- Nervous (brain, spinal cord, nerves)
NON-EXCITABLE:
- connective (bone, adipocytes, skin dermis)
- Epithelial (stomach lining, alveoli, epidermis, exocrine ducts, kidneys, intestines)

17
Q

examples of skeletal musc. not attached to bone or tendon?

A

diaphragm, tongue, anal sphincter
** attached to tissue

18
Q

Two cell types in nervous tissue? and function

A

Neurons: Generate+Conduct electrical impulses
Neuroglia: Do not conduct impulses – are support cells

19
Q

what forms the myelin sheath in CNS and PNS?

A

CNS - Oligodendrocytes
PNS - Schwann cells

20
Q

What tissue are glands made of?

A

epithelial tissue

21
Q

Features of epithelial tissue

A

** NO BLOOD VESSELS
- reproduces rapidly
- tightly packed cells thus tight junctions
**
underside linked to connective tissue by non-cellular BM

22
Q

Where are epithelial cells present?

A

alveoli, blood vessels, skin, mouth, lips, kidneys

23
Q

Types of epithelial cells + some of their locations

A

Simple+stratified:
-Squamous : Flat - for diffusion and filtration – also secretes lubricants
(alveoli, capillaries, lining of heart and lymphatic vessels)

-Cuboidal : For secretion and absorption
(In ducts, kidney tubules, secretory products of small glands)

-Columnar : Mainly absorption + also secretes mucous and enzymes
Ciliated:
- bronchi, uterine tubes, uterus
Non-ciliated/Smooth:
- stomach, digestive tract, bladder

24
Q

Types of stratified epithelial membrane cells

A

Keratinised:
– Dead cells present in a dry environment
– Ex. skin cells, hair, nails
Non-keratinised:
– Living cells in a moist environment
– In lips, the mouth, stomach, oesophagus

25
Q

exocrine glands - ducts or not? where they secrete? present where?

A

Exocrine glands secrete via ducts
- Secrete outside the body
- Like sweat, tear glands
– In the digestive tract (salivary glands, gastric glands)
– Liver (bile duct)

26
Q

endocrine glands - ducts or not? where they secrete? present where?

A

Endocrine glands dont secrete via ducts
- They secrete within the body
- Kidney — renin
- Pineal gland — Melatonin

27
Q

example of a gland that’s both endo and exo?

A

Pancreas
– secrete within the body
– Uses ducts

28
Q

Function of connective tissue? Location?

A
  • Binds, supports, protects, fills spaces, stores fat, produces blood cells
  • Throughout body btwn tissues
    – Has blood vessels and lots of extracellular proteins (like collagen)
    – Also has matrix in space btwn cells
29
Q

Examples of connective tissue

A
  • Skin dermis – mix of live and dead(keratinised) cells (**epidermis formed by epithelial cells)
  • Adipocytes – cells wrapped arnd fat globules
  • Bone (osteoblasts, osteocytes)
30
Q

Where do the following occur in a cell?
- glycosylation
- detoxification
- degredation
- post translational modifications
- substance modification

A
  • glycosylation – Golgi body
  • detoxification – SER
  • degredation – Lysosomes + Proteosomes (no cell memb)
  • post translational modifications – Glogi body
  • substance modification – SER
31
Q

Housekeeping genes definition?

A

Some general functions are common in all cells - the genes that encode for these common functions are called housekeeping genes
ex; Dna synthesis
generation of ATP
Cell division regulation