Oogenesis Flashcards
Name the earliest recognisable female germ cell
primordial germ cell
When does the primordial germ cell migrate to the genital ridge
by week 6 of embryo development
When is the proliferative phase of oogenesis completer in the female
during fetal/neonatal development
When is the first arrest in oocyte develoment
first meiotic prophase
What is the name of the oocytes arrest at prophase 1
primary oocytes
What is the name for the follicle containing these arrested primary oocytes
primordial follicle
When does regular recruitment of primordial follicles into a pool of growing follicles start to occur
puberty
What are the three stages of development of the follicle prior to ovulation
primary/preantral follicle
antral/secondary follicle
preovulatory follicle
which phase of follicular development prior to ovulation is the longest
preantral
preovulatory is the shortest
how large is the average premenopausal ovary
3cm
What is important to remember about the cytodifferentiation process in the female compare to male
Occurs along side the arrested meiosis rather than after completion of meiosis as in the female
What it the final size of the primary oocyte
60-120um
When does most of the growth of the primary oocyte occur
in the transition between the preantral and antral follicle - the follicle increases in size mostly due to growth of the primary oocyte which then reaches its final size
what is important to note about the growth of the primary oocyte in the preantral/antral transision
not accompanied by meiosis
what accounts for the increase in size of the primary oocyte then if meiosis does not occur?
dictyate chromosome are actively synthesizing large amounts of ribosomal and mRNA
