Onkoloji Flashcards

1
Q

Erkeklerde en sık kanserler?

A

Prostat
Akciğer
Kolorektal

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2
Q

Kadınlarda en sık kanserler?

A

Meme
Akciğer
Kolorektal

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3
Q

BRAF(+)ler

A

-Hairy cell lösemi
-Malign melanom
-Papiller tiroid kanseri
-Langerhans hücreli histiositoz
-Bazı kolon kanserleri

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4
Q

Lenfoma mutasyon ve genleri?
-Foliküler lenfoma
-Burkitt lenfoma
-Mantle hücreli lenfoma
-Anaplastik büyük hücreli lenfoma

A

-Foliküler lenfoma: t(14;18) > BCL2
-Burkitt lenfoma: t(8;14) > MYC
-Mantle hücreli lenfoma: t(11;14) > SiklinD
-Anaplastik büyük hücreli lenfoma: t(2;5) > ALK

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5
Q

Ckit(+)ler?

A

Sistemik mastositoz
GİST
Seminom
Disgerminom

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6
Q

Kardiyotoksisite yapan ilaçlar?

A

Antrasiklin (irreversibil KY) [=Adriamisin]
Trastuzumab (reversibil KY)
5-FU (koroner vazokonstriksiyon)

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7
Q

Akciğer toksisitesi yapan ilaçlar?

A

Bleomisin
Busulfan
Metotreksat

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8
Q

Nefrotoksik ilaç?

A

Sisplatin

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9
Q

Siklofosfamid ilişkili hastalıklar?

A

—AML (5., 7. kromozom)
—Hemorajik sistit
—Uygunsuz ADH

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10
Q

5-FU yan etkileri?

A

Koroner Vazokonstriksiyon
Akut serebellar toksisite

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