Onkologie obecně Flashcards

1
Q

NSE

A

-ovlivněno hemolýzou

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2
Q

GAPPS syndrom

A
  • gastric adenocarcinoma and proximal polyposis of the stomach
  • polypóza žaludku
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3
Q

ORR

A

-objective respons rate

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4
Q

HR

A

-hazard ratio

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5
Q

ir-RC

A

-immune-related response criteria

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6
Q

CTLA-4

A
  • cytotoxic T-lymphocyte antigen-4
  • negativní regulátor imunity
  • časná fáze aktivace T-lymfocytů při jejich aktivaci APC
  • především na úrovni lymfatických uzlin
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7
Q

PD-1

A
  • programmed death-1
  • exprimován na aktivovaných T- a B-lymfocytech
  • aktivován PD-L1, PD-L2 (exprimovány T- a B- lymfocyty, APC, NK a nádorovými buňkami)
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8
Q

HPD (hyperprogressive disease)

A

-vysoce agresivní chování nádoru po selhání léčby anti-PD1, anti-PD-L1

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9
Q
  • léčebná odpověď

- kontrola onemocnění

A

-

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10
Q

Studie fáze I

A

-

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11
Q

Studie fáze II

A

-

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12
Q

Studie fáze III

A

-

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13
Q

Studie fáze IV

A

-

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