Onkologie Flashcards

1
Q

R-CHOP

A

Rituximab, Ciclofosfamida, (Hydroxidaunorrubicina) Doxorubicina, Vincristina (Oncovin), Prednisona

Für Non Hodgkin Lymphom

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2
Q

Colchicin, Taxane und Vinca-Alkaloide wirken als…

A

Spindelgift (Prophase) / Hemmung der Polymerisation der Mikrotubuli

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3
Q

Methotrexat

A

Folsäure-Antagonist, hemmt die Dihydrofolatreduktase -> Mangel von Thymin -> Apoptose

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4
Q

Fluoruracil: Wirkung

A

Pyrimidinantagonist + Fluoro-UTP statt UTP in RNA

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5
Q

Actinomycin: Wirkungsmechanismus

A

Hemmt die prokaryotische RNA-Polymerase

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