ONH - TOXIC OPTIC NEUROPATHY

Question 1

what is toxic neuropathy?

Answer 1

damage to the optic nerve from toxic substances

Question 2

what causes toxic optic neuropathy?

Answer 2

• ethambutol
• chloramphenicol
• digitalis
• isoniazid
• streptomycin
• lead
• malnutrition
• alcohol

MEAL DISH

Question 3

symptoms of toxic optic neuropathy?

Answer 3

• acute onset of reduced vision (possible 20/400)
• VF defect (centrocecal)
• dyschromatopsia

Question 4

signs of toxic optic neuropathy?

Answer 4

• bilateral optic nerve pallor with swelling
• nerve fiber layer defects
• reduced contrast sensitivity
• possible APD – if optic nerve damage is asymmetrical

Question 5

tx for toxic optic neuropathy?

Answer 5

• d/c offending agent
• vision will spontaneously improve w/in 12 months but permanent visual changes may occur.