One Liners part 3

Question 1

Why is bacterial sinusitis major cause of orbital cellulitis?

Answer 1

Proximity + valveless orbital venous system

Question 2

Why would a SCD kid have 1 year long left leg pain that got worse?

Answer 2

Octeonecrosis or avascular necrosis of left hip is common in Sickle Cell Disease

Question 3

Alport’s has hearing and kidney problems. What happens to glomerular BM?

Answer 3

Splitting of BM + alternating areas of thinned and thickened capillary loops.
Often family hx of renal failure

Question 4

Breastfeeding has reduced risk of what cancer(s) in mother?

Answer 4

Breast and ovarian

- also fewer OM and respirator illness in newborn

Question 5

What biomarkers see in Juvenile Idiopathic Arthritis?

Answer 5

Anemia
Thrombocytosis
Hypergammaglobulinemia
Hyperferritinemia
Elevated ESR and CRP

Question 6

Causes of meningitis in infants < 3 months

Answer 6

Lysteria
GBS
E. coli
HSV

Question 7

Causes of meningitis in infants > 3 months?

Answer 7

Strep pneumo

Neisseria m.

Question 8

What do if suspect Strep Throat in 7yo?

Answer 8

Rapid Streptococcal Antigen Testing

If negative, f/u w/ throat culture due to limited sensitivity of RSAT

Question 9

How treat prolonged QT?

Answer 9

Propranolol and pacemaker

Question 10

What is Henoch-Schonlein Purpura?

Answer 10

IgA-mediated vasculitis

• see arthritis/arthralgia
• rash on legs

Question 11

How treat HSP for most pt’s?

- for severe symptoms?

Answer 11

NSAIDs + hydration

Systemic glucocorticoids + hospitalization

Question 12

First line treatment for SCD?

Answer 12

Hydroxyurea: increases fetal Hb
- main SE: myelosuppression
(neutropenia, anemia, thrombocytopenia)

Question 13

Why pain in SCD?

Answer 13

Sickling - polymerization of RBC’s - vaso-occlusion

Question 14

Wiskott-Aldrich Syndrome

Answer 14

W = X-linked
O = hypogammaglobulinemia
TT = thrombocytopenia
C = eczema

Question 15

Fanconi’s Anemia

Answer 15

F = P = Pancytopenia + macrocytosis

Question 16

Fanconi’s Anemia average age?

Answer 16

8yo = around the #6 for F

Question 17

Diamond-Blackfan anemia average age?

Answer 17

3 months (w/in first year of life)

Question 18

Why honeymoon cystitis?

Answer 18

Bacteria is introduced into the introitus (urethral opening) during intercourse.
Then get ascending infection often UTI = E. coli

Question 19

Each on neonate w/ vesicular clusters. Treatment?

Answer 19

Acyclovir

Question 20

What and when does S. aureus cause in potato salad?

Answer 20

Vomiting

- 1-6 hours later

Question 21

If seizure due to brain tumor, what kind of tumor esp if arm/leg weakness?

Answer 21

Think Astrocytoma

- very common, benign

Question 22

Most common vaginal foreign body in young child? like 3-4 years old

Answer 22

Toilet paper, small toys

Question 23

Damage in shaken baby syndrome?

Answer 23

Shearing of dural veins = coup-contrecoup injury w/ brain impact on skull

Bilateral regional hemorrhages

Question 24

How prove innocent murmur?

Answer 24

Murmur decreases w/ decreased preload (decreased venous blood return)
- standing, Valsalva

Question 25

Why see howell-jolly bodies in 8yo w/ SCD?

Answer 25

Splenic auto infarction by age 5

- spleen no longer clears nuclear remnants in RBC’s = howell-jolly bodies

Question 26

Radiopaque tablets in stomach of 3yo; next step?

Answer 26

Deferoxamine

- pregnant mom has pre-natal vitamins at home