Oncology: Principles In Onco Rehab Pt. 3 Flashcards
PT Imps in terms of Oncology
- Type and Stage of Cx
- Gen health
- QOL
- Financial and social strains
- Preventative, Restoratitve, Supportive, Palliative
- SEs from tx
- Discharge planning from ALL settings
Blood Clots
2 that we are Concerned W/:
- DVT
- PE
Deep Vein Thrombosis
DVT
Explaiin
- Clot of cellular material bound to fibrin located in DEEP VEINS
-
Sx’s:
- edema
- erythema
- PAIN
Pulmonary Embolism
PE
Explain:
Blood clot which obstructs the Pulmonary aa/vein
-
Sx’s:
- dypnea
- LOW O2sats
- tachycardia (reflex tachy)
- chest pain***
DVT
PE
Tx’s
- AntiCOAGULANTS (blood unable to clot)
- IVC filter (Inf. Vena Cava)
- for LE origin ONLY
VASCULAR
DVTs
Incidence in Cx Pts
- TWICE AS LIKELY TO DEVELOP DVTs***
- FREQ. complication
- 2nd leading cause of death***
- 90% of pts expe an INC in clotting activity
- MORE COMMON:
- ovarian
- pancreatic
- lymphatic
- liver
- stomach
- colon cx’s
Vascular complications
DVTs
Causes of a Hypercoagulable State
- Immobility
- SOME tumors release subs that INC blood’s ability to clot
- Sx OR CHEMO can injure vessel walls—> triggers blood coagulation
- Cx therapy can DEC body’s ability to produce adequate coagulants
Vascular comps
DVTs
PT imps:
- Awareness of Tx***
- Monitor approp. blood values
- Monitor SPO2 and HR***
Blood Clot forming
Embolus traveling thru heart INTO lung vessels
see pics
Sx Resection GOALS:
WHAT ARE THEY TRYING TO ACHIEVE?
CLEAN MARGINS
- Trying to achieve clean margins
- to be sure ALL cx cells removed
-
Tumor can be resected completely BUT
- ALSO want to resect an area of clean tissue or non-cx tissue to see if ACTUALLY CLEAN
SEs from Sx
- Loss of Function
- disfigurement or deformities
- PAIN
- infection
- Risk of bleeding or hemorrhage
- Fatigue
- dev. of scar tissue
PT Implications Following Sx
- EARLY mobility and pulm hygiene
-
Respiratory Considerations:
- Chest PT + Airway clearance
- Chest wall excursion (lateral costal breathing)
-
Soft tissue restrictions:
- ROM restricts
- WB restricts
- Scar restriction (after healing)
-
Weakness:
- Nerve resections
- Nerve traction injuries
- **Psychosocial implications
Chemotherapy
Common SE’s
**remember Chemo attacks ANY rapidly dividing cells (think GI, Hair follicles)
- PAIN
- Fatigue
-
Bone marrow suppression
- Infection
-
Alopecia**
- remember hair follicles attacked–rapidly dividing
- Infertility
-
GI effects**
- remember hair follicles attacked–rapidly dividing
- nausea, vom, constipation, anorexia
- Peripheral neuropathy
- DECd bone density
- skin rashes
- Wt. gain OR loss
- Jt pain
- Sexual dysf
- Hemorrhage
Hematological Considerations:
Bone Marrow Suppression:
3 things come from this
- Anemia
- Thrombocytopenia
- Leukopenia/Neutropenia
Anemia
What is it?
LOW RBC Count
Anemia
Lab values: HgB
Norms: M vs F?
MALE==14-17 g/dL
FEMALE==12-16 g/dL
Anemia
S/S
(Anemic)
- FATIGUE
- irritability
- lightheadedness
- HA
- Loss of concentration
- pallor
- SOB
Anemia
PT Imps:
- Monitor VITALS!!!
- RR INC, HR INC, SaO2 DEC
- Monitor LAB VALUES/Tx
- Monitor FATIGUE LVLS
NOTE: Have to use RPE ***
Thrombocytopenia
what is it?
LOW Plt count
- NORM== 150,000-400,000 mm^3
Thrombocytopenia
LOW Plts
S/S
- Bruising
- Bleeding—if too low
- Petechiae
- sm. raised rash on skin
-
microtrauma to superficial blood vessels
- __INAD. Plts
Thrombocytopenia
LOW Plt count
PT Imps:
- Monitor LAB VALUES/Tx
- FALL PRECAUTIONS
- train balance but NOT high lvl
- Focus on Functional Mobility
- __NO risky activity
How can you remember Plts easily??
They are YELLOW
SEE PICS
Leukopenia/Neutropenia
What is this ?
LOW WBC Count
- NORM== 3.5k to 10.5k cells/mcL
Leukopenia/Neutropenia
LOW WBCs
S/S
- Freq INFECTIONS
- Fevers
- Throat/mouth sores bc DECd ability to fight infections
Leukopenia/Neutropenia
LOW WBCs
PT implications:
- Reverse/Protective Isolation—Neutropenic Precautions
- PROVIDER (PT) dons PPE to protect pt
- Creative tx interventions
Bone Marrow Suppression Guidelines
aka Blood Counts outside normal ranges:
WBCs
- <5k–NO EX permitted
- >5k–light ex, progressive to resistance
Bone Marrow Suppression Guidelines
aka Blood Counts outside normal ranges:
HgB:
- <7.5g/dL== NO EX permitted
- 7.5-10g/dL== Lt ex, focus on functional mobility
- >10g/dL == Resistive ex permitted
Bone Marrow Suppression Guidelines
aka Blood Counts outside normal ranges:
Plts:
- <20k– NO EX OR ADLs/walking
- 20-30k– Lt ex, AROM, walking
- 30-50k– MOD ex, aquatic, stationary bike
- 50-150k– Progressive resist ex’s, swimming, bike
- >150k– Unrestricted normal act.
Bone Marrow Suppression Guidelines
aka Blood Counts outside normal ranges:
INR
- >4.0– NO EX permitted
Radiation Therapy
Common SEs
And what can occurr from each.
- PAIN
- Fatigue
-
Bone marrow suppression
- INFECTION
- Local hair loss
- attacks rapidly dividing cells
- Delayed wound healing
- DECd bone mass/strength
- Skin changes
- fibrosis
- erythematous skin
- fragile skin
- myofascial adhesions
- GI changes–attacks rapidly dividing cells
- diarrhea
- vom
- PRO deficiency
- anorexia
- Wt loss
- AVN: loss of blood supply==necrosis
Radiation Therapy
Common SEs
Radiation Myelitis
- damage to small blood vessels in spinal column
- –> DECd blood flow
- –> necrosis
-
–> demyelination
- –> sensory dysf and weakness
Radiation Therapy
Site Specific SEs
Abdomen and Pelvis
- Nausea
- bladder discomfort/dysf
- Sexual dysf
Radiation Therapy
Site Specific SEs
Head and Neck
- Diff eating
- dental hygiene
- Dry mouth
Radiation Therapy
Site Specific SEs
Breast
- DECd shoulder ROM
- Soreness
- Lymphedema
Radiation Therapy
Site Specific SEs
Chest
- Swallowing diff
- SOB***
Radiation Therapy Considerations
- Burns/blisters
-
Radiation fibrosis/necrosis
- brain
- lungs
- trismus
PT Implications following Radiation Therapy
Radiation Induced Fibrosis
*stuck, tight adhesions
Specifically what/where?
-
Trismus
- unable to open mouth by 30cm or 3knuckles
- Limtd cervical ROM
- Head drop—-literally
- Limtd chest wall excursion
-
Osteoradionecrosis
- Jaw bone
- Neuralgia
- loss of nerve conduction
- loss of flexibility
Radiation Therapy
Common SEs
CNS Effects: 3
- Radiation Necrosis
- Encephalopathy
- Myelopathy
Radiation Therapy
Common SEs
CNS effects: Radiation Necrosis
Lg mass of dead tissue that forms @ SITE of irradiated tumor
Radiation Therapy
Common SEs
CNS Effects: Encephalopathy
FOCAL neuro sx’s assoc’d w/ white matter changes (DECd)
Radiation Therapy
Common SEs
CNS Effecs: Myelopathy
Functional or pathological disturbance of Spinal Cord
**can be transient (short term) or chronic
Breast Cx: Radiation SEs
LEFT= burn + fibrosis
RIGHT= radiation burn
Radiation SEs
Radiation desquamation + skin changes
see pics
Radiation Therapy SEs
Pulmonary fibrosis
- Possible after lung or breast radiation
- NO current tx’s
PT Implications
Radiation Therapy
PRECAUTIONS:
- Blood values/lab results
- Infection control
- PAIN
- fatigue
- WB status
Radiation Therapy: PT Implications
Interventions:
ROM
FALL PREVENTION, Assess for approp. AD
pt+fam edu
PT implications Following Radiation Therapy
- Nerve injury
- weakness
- pain
- parasthesias
- Lymphedema
- Fatigue
- Compromised skin integrity
- Psychosocial imps
Stem Cell Transplant usually combined w/….
HIGH DOSE CHEMO
SES from Stem Cell Transplant
-
GVHD
-
Graft vs. Host Dis.
- body REJECTS stem cells
-
Graft vs. Host Dis.
- Immunosuppression
- Isolation
- Delayed wound healing
- Nausea and vom
- Osteoporosis
- 2* malignancy
Graft vs. Host Disease
GVHD
-
Transplant Rejection:
- Donor cells (graft) recognize body’s cells (host) as foreign and implement immulogic attack
- skin, liver, gut
-
Tx:
- INCd immunosuppressive drugs