Oncology Flashcards

1
Q

Doxorubicin side effects

A

Dilated cardiomyopathy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Osteomyelitis x-ray

A

periosteal reaction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Osteosarcoma x-ray

A

Sunburst
metaphysis or growth plate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Ewing sarcoma

A

onion skinning
Mottled
diaphysis and axial

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Langerhans cell histiocytosis

A

1-Rash
2-neutropneia
3-Skull abnormalities
4-DI (polyuria and polydipsia)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Neuroblastoma

A

Opsoclonus-myoclonus
Dx: urine VMA/HVA
or MIBG scintigraphy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

12-year-old female, with fatigue, diffuse lymphadenopathy, HSM, supraclavicular lymph node, normal Hb and WBC, and low normal platelets 150s. Viral studies (EBV) normal. What is the NEXT best step?

A

CXR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

WAGR

A

Wilams Tumor
Aniridia
GU abnormalities
retreated mentally

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

5yo with LCH s/p chemotherapy with vinblastine and prednisone 1 year prior, currently in remission. Presenting with polyuria and polydipsia. What is the cause?

A

Central diabetes insipidus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Kid with Burkitt’s and TLS. Urine pH 7.0. What’s next.

A

Rasburicase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Features of Tumor lysis syndrome

A

Remember cells are bursting
1-high K
2-high phosphate
3-low ca
4-high ca in the urine
5-high LDH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Tumor lysis management

A

Allopurinol: decreases production of urate
Rasbirucase: binds urate to excrete it

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

A child with ALL finished chemo 1 month ago and is exposed to Varicella. How do you treat?

A

VZIG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Examples of live vaccine

A

MMR, varicella, rotavirus
Nasal flu
BCG, Zoster

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Chemotherapy that causes low sodium and vomiting

A

Cyclophosphamide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Vincristine side effect?

A

Peripheral neuropathy

17
Q

14 y.o boy w supraclavicular LN. What is your next step

A

CXR

18
Q

Child with head tilt, ataxia, nystagmus. Most likely diagnosis:

A

Cerebellar astrocytoma

19
Q

Teenager with generalized lymphadenopathy and right supraclavicular node. What to do next?
what is the next step in evaluation NOT what would give the dx?

A

a.CXR
b. BMA
c. CT abdo

20
Q

Which cancer will most likely have bone marrow infiltration

A

neuroblastoma

21
Q

What is a risk factor for child leukemia?
a. parent treated for leukemia
b. in utero radiation
c. maternal alcohol
d. NF type 1

A

in utero radiation

22
Q

16 y.o. boy undergoing treatment for non-Hodgkin’s lymphoma. Forty-eight hours after his last chemotherapy, he develops mild dysuria and hematuria. Platelet count was 90 pre-treatments. He is happy and well-looking. He is sexually active. What is the most likely because of his hematuria:

A

cyclophosphamide-induced hemorrhagic cystitis

23
Q

Child with aniridia, what investigation will this child need regularly?

A

Abdominal U/S