Oncology Flashcards

1
Q

Radiation dose:

Mets

A

25-30 Gy

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2
Q

Radiation dose:

STS

A

50 Gy pre-op
60 Gy post-op

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3
Q

Radiation dose:

HO

A

5 Gy

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4
Q

Mnemonic for diaphyseal lesions

A

AEIOUY

Adamantanimoa
Eosinophilic granuloma
Infection
Osteomyelitis
EUings
fibrous dYsplasia, lYmphoma, mYeloma

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5
Q

tumors in anterior elements of spine

A

Giant cell, mets

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6
Q

tumors in posterior elements of spine

A

OO/OB, ABC

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7
Q

3 tumors with predilection for tibia

A
  1. Chondromyxoid fibroma
  2. Non-ossifying fibroma
  3. Adamantinoma
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8
Q

Size to perform an excisional biopsy

A

<3 cm

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9
Q

Key cell in chondrosarcoma

A

Kissing cell, binucleate

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10
Q

Mnemonic for small round blue cells

A

LERNM

Lymphoma
Ewings
Rhabdomyosarcoma
Neuroblastoma
Myeloma

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11
Q

IHC:

Beta catenin

A

Desmoid fibromatosis

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12
Q

IHC: CD34

A

Hemangioma

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13
Q

IHC: USP6

A

Aneurysmal bone cyst

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14
Q

IHC: Loss of INI1

A

Epithelioid sarcoma

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15
Q

IHC: Desmoid fibromatosis

A

Beta catenin

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16
Q

IHC: Hemangioma

A

CD34

17
Q

IHC Leiomyosarcoma

A

SMA Smooth muscle actin

18
Q

IHC: ABC

A

USP6

19
Q

IHC: Epithelioid sarcoma

A

Loss of INI1

20
Q

Translocation myxoid liposarcoma

A

t(12;16)
TLS-CHOP

21
Q

Size cutoff in AJCC classification

A

8 cm

> 8cm = Stage IIB

22
Q

Differential for ABC

A

Must rule our telangiectiasic osteosarcoma

ABC is positive for USP6

23
Q

Multiple Enchondromas

A

Ollier’s
Mafucci’s

24
Q

Multiple osteochondromas

A

MHE

25
Q

Mnemonic for vertebra plana

A

MELT

Mets, MM
Eosinophilic granuloma, Ewings
Lymphoma, leukemia
Trauma, tuberculosis

26
Q

Punched out lesions

A

<30- LCH
>30 - Multiple myeloma

27
Q

Origin of giant cell

A

Preosteoblastic mononuclear cell

28
Q

Mnemonic for sarcomas with lymph node mets

A

SCARE

Synovial sarcoma
Clear cell sarcoma
Angiosarcoma
Rhabdomyosarcoma
Epithelioid sarcoma

29
Q

Treatment of chondromyxoid fibroma

A

Shark bite
curettage + bone graft/cement

30
Q

Epiphyseal lesion

A

<30 = Chondroblastoma
>30 = Giant cell tumor

31
Q

Tx of chondrosarcoma

A

Surgery Only
Chest imaging for staging

32
Q

Differential for adamantinoma

A

Osteofibrous dysplasia- rimming osteoblasts

Adamantinoma- no rimming osteoblasts, keratin staining, nests of cells

33
Q

Disorder with fibrous dysplasia

A

McCune Albright

Coast of Maine Cafe Au lait spots
Endocrine abnormalities
Shepherd’s crook deformity in proximal femur

34
Q

Hemangioma of bone in spine

A

Jail bar appearance

35
Q

Histology of Chordoma

A

Physaliferous cell

36
Q

Buzzwords for langerhans cell histiocytosis

A

Birbeck granules on electron microscopy, coffee bean nuclei

37
Q
A