Oncology Flashcards
Paratesticular rhabdomyosarcoma (RMS), greater than 10yo, next step?
Ipsilateral RPLND
How much ADT do men with HR PCa need if undergoing ADT?
1.5-3 years
Bonus: can be conventional fractionation or moderate hypofractionation (no ultra-hypofractionation)
Poor risk factors for mRCC
- LDH >1.5 upper limit of normal
- Anemia
- Serum Ca > 10
- Time from diagnosis of RCC to mets less than 1 year
- Karnofsky score of 60 or 70 ???
- Mets to multiple organs
Enzalutamide vs darolutamide: which one increases seizure risk?
Enzalutamide
Genes associated with Wilm’s tumor?
WTR1
WTR2
What do areas of low density (HU < -30) within a renal mass mean?
This is fat –> AML
ECOG classification
0 - Fully active, without restriction.
1 - Completely ambulatory, but restricted in physically strenuous activity. Able to carry out work of a light or sedentary nature such as light housework or office work.
2 - Ambulatory and capable of all self care but unable to carry out any work activities. Out of bed > 50% of waking hours.
3 - Capable of only limited self-care and confined to a bed or chair ≥ 50% of waking hours.
4 - Completely disabled. Cannot carry on any self-care. Totally confined to bed or chair
5 - Death
Urethral carcinoma, clinically normal inguinal nodes –> next step?
No role for prophylactic ILND in urethral cancer, unlike in penile cancer.
Lymphatics from the anterior urethra drain into the deep and superficial inguinal LNs.
Indocyanine green should be avoided in patients with allergy to ______?
Iodine
Proximal limit for extended pelvic lymph node dissection (for bladder cancer)?
IMA
What do you need to monitor while on sunitinib?
Thyroid stuff …. T4 and TSH
PSA bounce?
Defined as a rise greater than 0.2 ng/ml followed by a durable decline and is especially common after brachytherapy, where it is reported to occur in 24% to 35% of men.
These can start any time from 9 to 30 months after brachytherapy with the majority of patients having a cumulative PSA rise of not more than 2 to 3 ng/ml.
