oncogenes Flashcards

1
Q

BCR-ABL

A

Tyrosine kinase

CML, ALL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

BCL-2

A

Anti-apoptotic molecule

follicular lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

BRAF

A

Serine/threonine kinase

Melanoma, non-hodgkin lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

c-kit

A

cytokine receptor

gastrointestinal stromal tumor (GIST)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

c-myc

A

TF

burkitt lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

n-myc

A

TF

neuroblastoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

l-myc

A

TF

lung tumor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

HER2/neu (c-erbB2)

A

tryrosine kinase

breast, ovarian, gastric carcinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

RAS

A

GTPase

colon, lung, pancreatic cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

RET

A

tryrosine kinase

MEN 2A, MEN2B, medullary thyroid cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly