oncogenes Flashcards
1
Q
BCR-ABL
A
CML, ALL
Tyrosine Kinase
2
Q
bcl-2
A
Follicular and undifferentiated lymphoma
Anti-apoptosis gene
3
Q
BRAF
A
Melanoma
Serine/threonine kinase
4
Q
c-kit
A
Gastrointestinal stromal tumor
Cytokine receptor for stem cell factor
5
Q
c-myc
A
Burkett lymphoma
transcription factor
6
Q
HER2/neu
A
Breast, ovarian, and gastric carcinoma
tyrosine kinase
7
Q
L-myc
A
Lung Tumor
transcription factor
8
Q
N-Myc
A
Neuroblastoma
transcription factor
9
Q
ras
A
Colon cancer, lung cancer, pancreatic cancer
GTPase
10
Q
ret
A
Men 2A and 2B
Tyrosine kinase