Oncogenes Flashcards by Sarah Lopez | Brainscape

Q

BCR-ABL

A

Tyr Kinase

CML, ALL

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Q

BCL-2

A

Antiapoptotic

Follicular and undifferentiated lymphomas

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Q

BRAF

A

Ser/Thr kinase

Melanoma, Non-Hodgkin Lymphoma

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Q

c-kit

A

Cytokine receptor

GI stromal tumor

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Q

c-myc

A

TF

Burkitt lymphoma

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Q

HER2/neu (c-erbB2)

A

Tyr kinase

Breast, ovarian, gastric carcinomas

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Q

L-myc

A

TF

Lung tumor

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Q

N-myc

A

TF

Neuroblastoma

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Q

RAS

A

GTPase

Colon, lung, pancreatic cancers

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Q

RET

A

Tyr kinase

MEN 2A and 2B, medullary thyroid cancer

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