OMM Research Flashcards
Methods: 406 pneumonia patients at 7 community hospitals receiving OMT or conventional care only (CCO)
Results: Significant difference in LOS and antibiotic duration when comparing OMT group vs CCO group
Conclusions: Per protocol analysis found significant differences between OMT and CCO groups when looking at LOS, antibiotic duration, and respiratory failure/death
Study: Multicenter Osteopathic Pneumonia Study in the Elderly (MOPSE)
Methods: COPD patients undergo pulmonary rehab (PR) + OMT or just PR
Results: PR + OMT group showed an increased 6 min walk test and a significant difference in decreased RV when compared to the other group
Conclusions: PR + OMT improves exercise capacity and reduces RV in severely impaired COPD patients compared to PR alone
Study: OMT effectiveness in severe COPD
Methods: 55 patients who underwent major GI operation received OMT or not
Results: Significant difference in time to flatus and postoperative hospital LOS in OMT group when compared to non-OMT group
Conclusions: OMT applied after major GI operation is associated with decreased time to flatus and postoperative hospital LOS
Study: Effect of OMT on incidence of postoperative ileus and hospital LOS in general surgery patients
Instead of documenting pain, ________ or ________ can be followed.
Financial outcomes, hospital length of stay
Methods: 400 pregnant women in third trimester received OMT or placebo
Results: Back pain was significantly improved in OMT group compared with usual care group
Conclusions: OMT was effective for mitigating pain and functional deterioration compared with usual care group
Study: Pregnancy Research on Osteopathic Manipulation Optimizing Treatment Effects (PROMOTE)
Methods: Healthy adults assigned to rib raising or light touch
Results: Significant decrease in α-amylase activity in those who received rib raising compared to those who did not
Conclusions: SNS activity may decrease immediately after rib raising, but HPA and parasympathetic activity are not altered
Study: Effects of rib raising on the autonomic nervous system
________ treatment can make it easier to conduct studies, however, OMT isn’t performed in such a rigid fashion normally.
Protocol-based
Documenting changes can be difficult due to ________ being subjective.
Pain/symptoms
________ analysis looks at all individuals in a study, regardless of whether they dropped out or not.
Intention to treat
Methods: Subjects with FEV1% <70% received OMT or sham
Results: OMT group had significant decrease in forced expiratory flow and a significant increase in residual volume and TLC compared to the sham group
Conclusion: Overall worsening of air trapping 30 mins after OMT session
Do these results mean that OMT is bad for those with COPD?
Study: Immediate effects of OMT in elderly patients with COPD
No, it shows that the techniques used may not be suitable for this specific age group with this disease
What are the two major complications of randomized controlled trials?
Noncompliance and missing outcomes
In the future, ________ will help OMT studies remain objective, quantifiable, and reproducible.
Biomarkers
One of the problems with OMM research is in picking a ________ for the experimental group to be compared against.
Placebo
Methods: 39 subjects got Hep B vaccine with lymphatic pump or not
Results: 50% of those who received pump had a response with average titer of 374 mlU/mL. Those who did not receive pump had an average of 96 mlU/mL
Conclusions: Lymphatic pump may result in higher titers after vaccination
Study: Effect of lymphatic and splenic pump techniques on the antibody response to hepatitis B vaccine
________ is a subset of ITT analysis and induces only the people who completed the study.
Per-protocol population
