OME endocrine Flashcards

1
Q

tx for graves dz

A

PTU or methimazole

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2
Q

tx for thyroid storm

A

propranolol, PTU, steroids

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3
Q

causes of cushing syndrome (4)

A

ACTH: pituitary vs ectopic, iatrogenic, adrenal tumor

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4
Q

cushing syndrome initial test

A

no suppression w/ low dose dex supp test

+ late night salivary cortisol OR 24hr urine

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5
Q

cushing syndrome w/ nml ACTH

A

primary hypercortisolism (adrenal tumor)

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6
Q

cushing syndrome w/ high ACTH

A

high dose dex supp test

  • fails = ectopic
  • suppressed = cushing dz
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7
Q

acute presentation hypocortisolism: BP, etc

A

hTN, N/V, coma

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8
Q

chronic presentation addisons: BP, Na, K

A

hTN, low Na, high K

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9
Q

addisons initial test

A

AM cortisol = low

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10
Q

addisons secondary test

A

cosyntropin stim test
inc cortisol = ant pituitary
no change = adrenal -> image

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11
Q

tx for addisons

A

cortisol + fludrocortisone (if adrenal)

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12
Q

HTN + hypokalemia

A

Conn’s syndrome (hyperaldo)

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13
Q

aldo:renin <10

A

renovascular

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14
Q

aldo:renin >30

A

conn’s syndrome

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15
Q

HA, HTN, palpitations, sweating

A

pheo

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16
Q

metformin side effects

A
  • diarrhea

- lactic acidosis in CHF, CKD

17
Q

glypizide MOA, side effects

A

sulfonylurea - inc insulin release

SE: hypoglycemia

18
Q

glitazone side effects

A

weight gain, CHF

19
Q

-gliptins MOA, side effects

A

DDP4-i (DDP4 breaks down GLP1), weight neutral

20
Q

-glutides MOA, side effects

A

GLP1-a, weight loss

21
Q

-glifozin MOA, side effects

A

SGLT2-i (kidney glu absorption) -> promote glu excretion

SE: GU, dehydration