Olfaction (1) Flashcards
1
Q
Which molecule is the OR7D4 receptor specific to?
A
Androstenone
2
Q
What are the two routes of air to the OE?
A
Orthonasal - through nostrils
Nasopharynx - from back of mouth
3
Q
Which nerve innervates the OE and which bone structure does it pass through?
A
Olfactory nerve
Through cribriform plate of ethmoid bone
4
Q
What are the 3 cell types in the OE?
A
OR neurons
Basal cells
Supporting cells
5
Q
What is the role of basal cells?
A
Stem cells - regenerate OR neurons/supporting cells
6
Q
What is the role of supporting cells?
A
Secrete odorant-binding proteins - bind to hydrophobic odorants - aid movement through mucosa to receptors
Release enzymes - detoxify harmful molecules
