Neuroplasticity (2)

Question 1

What are the symptoms of dystonia?

Answer 1

Cramps, muscle sequencing problems, involuntary movements during task - due to inappropriate agonist/antagonist co-contraction

Question 2

What is the name of the perilesional brain area in a stroke?

Answer 2

Penumbra

Question 3

What is diaschisis?

Answer 3

Distant motor areas connected to infarcted brain area have prolonged but reversible depression of neuronal activity

Question 4

What is the effect of low frequency theta burst stimulation?

Answer 4

LTD

Question 5

What is the effect of high frequency theta burst stimulation?

Answer 5

LTP

Question 6

What is the effect of continuous theta burst stimulation?

Answer 6

LTD

Question 7

What is the effect of intermittent theta burst stimulation?

Answer 7

LTP

Question 8

What is the effect of D-amphetamine on plasticity?

Answer 8

Increases synaptophysin

Axonal growth and synapse formation - task improvement

Question 9

What is NogoA and how is it targeted after stroke?

Answer 9

Growth inhibitory protein

Inhibitors cause increase regeneration, axonal sprouting, and structural plasticity in CNS

Question 10

What is the effect of BDNF on plasticity?

Answer 10

In mice

Supports survival of existing neurons and encourages new neuron growth