Old Test I Flashcards
Test I Review
Unless the primary health provider or clinical pharmacist directs otherwise, the nurse should inform the patient to take oral medications with:
Water
The nurse explains to the patient receiving an IV injection that the action of the drug begins
Almost immediately
A type of drug classification that is based on the chemical make-up or activity of the drug.
Pharmacologic
When would it be appropriate for an individual to purchase and use OTC medication
Short term treatment for minor illness.
Desired pharmacotherapeutic benefit from time-release drugs
To help reduce the irritating effects of a drug on the GI lining
True or False
- Liver metabolism and renal elimination are the two most important mechanisms involved in the termination of drug action
True
Primary piece of legislation governing drugs and drug distribution in Canada
Food and Drug Act 1953
To avoid confusion, what category of drug name should the nurse refer
Generic Name
A water soluble vitamin whose pharmacologic action is to prevent pernicious anemia
Vitamin B12
A vitamin that regulates the absorption and subsequent use for Calcium and Phosporous
Vitamin D
A vitamin that is essential for night vision and for normal vision because its part of one of the major retinal pigment.
Vitamin A
The drug half-life is the amount of time required for 50% of the drug to _____
be eliminated by the body
What is the reason for diff in dosing between IV and Oral drugs
Loss of oral drugs through GI tract and first pass effect
Pts with peripheral vascular disorder would most probably have problems in which phase of pharmacodynamics
Distribution
What TI should a drug possess to be considered safe
TI much greater than 1
When would a nurse monitor for adverse effects of the drug
Peak
Grapefruit juice ____ the livers P450 system, which metabolizes anti-hypertensive medication
inhibits
True or False
Lipid solubility doesnt affect drug absorption
True
Anti-depressant improve mood by increasing levels of:
NE and Serotonin
Which class of anti-depressants has as it most adverse effects, anticholinergic effects such as dry mouth, sedation and urinary retention
TCAs
What is the mechanism of action of the pharmacologic class of drugs to which fluxetine HCL (Prozac) and Pertraline (Zoloft) belong
To selectively only block serotonin re uptake. SSRIs
What is the mechanism of action of the drugs impramine and trimipramine
They inhibit re uptake of NE and serotonin
Which condition may be avoided when you avoid tyramine high foods such as aged cheese, avocados, processed meat when taking MAOI depressants
Severe Hypertension