Old Missed TQ Flashcards
The RNA of the small ribosomal RNA subunit is synthesized by…
a) RNA polymerase I
b) RNA polymerase II
c) RNA polymerase III
d) RNA polymerase IV
E) RNA polymerase V
a) RNA polymerase I
The RNA of the mitochondrial RNA is synthesized by... a) RNA polymerase I b) RNA polymerase II c) RNA polymerase III d) RNA polymerase IV E) RNA polymerase V
b) RNA polymerase II
The RNA of the tRNA is synthesized by... a) RNA polymerase I b) RNA polymerase II c) RNA polymerase III d) RNA polymerase IV E) RNA polymerase V
c) RNA polymerase III
Which of the following would be a good definition of a gene?
a) A gene is a region of DNA sequence in which mutations may cause a disease
b) A gene has DNA sequence which encodes a protein
c) A gene has DNA sequence that contains a regulatory region
d) A gene is a region of DNA that contains introns
e) none of the other responses is correct
e) none of the other responses is correct
A microRNA
a) is an RNA whose role is in transcription and post transcriptional regulation of gene expression
b) encodes a small message utilizing a genetic code
c) has sequence added to it to enable linkage to an amino acid
d) refers to RNA in the small ribosomal subunit
e) refers to small RNAs in the small and large ribosomal subunit.
a) is an RNA whose role is in transcription and post transcriptional regulation of gene expression
A GCG in the gene sequences of the PROMOTER region of gene A is mutated to a GAG (in the genetic code GG is an alanine and the GAG is a glutamate). The result might be
a) misregulation of gene A
b) a silent mutation
c) a missense mutation
d) a nonsense mutation
e) altered stability of the mRNA transcribed from gene A
a) misregulation of gene A
The steps of tRNA processing are…
a) cleavage, addition and base modification
b) capping, polyadenylation and splicing
c) binding, bonding and translocation
d) coding, complementing and repeating
e) charging, base pairing and folding.
a) cleavage, addition and base modification
The steps of mRNA processing are…
a) cleavage, addition and base modification
b) capping, polyadenylation and splicing
c) binding, bonding and translocation
d) coding, complementing and repeating
e) charging, base pairing and folding.
b) capping, polyadenylation and splicing
The steps of amino acid synthesis are…
a) cleavage, addition and base modification
b) capping, polyadenylation and splicing
c) binding, bonding and translocation
d) coding, complementing and repeating
e) charging, base pairing and folding.
c) binding, bonding and translocation
Which of the following antibiotics do not act on ribosomes?
a) gentamycin
b) tetracycline
c) rifampicin
d) Ketek
e) chloramphenicol
c) rifampicin
One of the causes of beta-thalessemia is
a) a mutation that ecreases methylation of the FMR1 gene.
b) a nonsense mutation in the beta-thalas gene
c) a silent mutation in the beta globin coding sequence (CDS)
d) a mutation that increases the stability of beta thalas mRNA
e) a mutation in the promoter region of gamma-globin
e) a mutation in the promoter region of gamma-globin
An mRNA
a) cannot base pair with another strand of RNA
b) is made by the polymerizaiton of adenosine, cytidine, guanosine and thymidine triphosphates
c) results from the polymerization of amino acids
d) has untranslated regions (UTRs)
e) is NOT used as a template to make a protein
d) has untranslated regions (UTRs)
There is a mutation in the PROMOTER region of Gene A changing the sequence from UUA to UUC. Which of the following might result? (In the genetic code, UUA encodes leucine, and UUC encodes phenylalanine).
a) regulation of Gene A is altered
b) the protein encoded by Gene A has a missense mutation
c) the protein encoded by Gene A has a nonsense mutation
d) the protein encoded by Gene A has a silent mutation
e) the stability of the transcript encoded by Gene A is altered.
a) regulation of Gene A is altered
Which of the following types of RNA are not involved in translation?
a) NOT AN ANSWER
b) transfer RNA (tRNA)
b) ribosomal RNA (rRNA)
c) messenger RNA (mRNA)
e) small nuclear RNA (snRNA)
e) small nuclear RNA (snRNA)
The infectious disease diphtheria is harmful to humans because diphtheria toxin can
a) inhibit prokaryotic translocation
b) inhibit eukaryotic translocation
c) interere with ergulation of cholesterol synthesis
d) methylate propomoter reions
e) demethylate promotor regions.
b) inhibit eukaryotic translocation
The active form of the “maturation promoting factor” (MPF) helps initiate mitosis by enzymattically _______ many protein structures such as tubulin and nuclear laminins.
a) hydrolyzing
b) methylating
c) phosphorylating
d) carboxylating
e) glycosylating
c) phosphorylating
A tRNA (transfer RNA) has
a) an mRNA (messenger RNA) on one end and an rRNA (ribosomal RNA) on the other
b) only silent mutations
c) a sequence that enables it to bind transcription factors
d) an anticodon RNA sequence on one end and the corresponding amino acid on the other
e) RNA polymerase on one end and an amino acid on the other.
d) an anticodon RNA sequence on one end and the corresponding amino acid on the other
Tetracyline inhibits
a) formation of covalent bonds by RNA polymerase
b) binding of the large ribosomal subunit to the complex including small ribosomal subunit and mRNA
c) proper function of vestibular and cochlear cells of the ear, and proximal tubular cells of the kidney
d) binding of aminacyl tRNAs
e) binding of TFIIA
d) binding of aminacyl tRNAs (in transcription)
Which of the following is an antibiotic that inhibits translation (hint: an adverse effect associated with this drug is fatal aplastic anemia)?
a) formivirsen (Vitravene)
b) chloramphenicol
c) sulfamethoxazole (A sulfa drug)
d) rifampicin (Rifampin)
e) methotrexate
b) chloramphenicol
Which of the following antibiotics binds to ribosomes?
a) ciproflaxacin
b) rifampicin
c) Bactroban
d) Agmentin
e) erythromycin
e) erythromycin
In the PROMOTER region of the beta-globin gene of some individuals, there is a mutation 88 base pairs up stream of the transcription start site resulting in a sequence of ATC where most humans have the sequence ACC. IN the genetic code AC encodes the amino acid theronine and the AUC encodes the aminoacid isoleucine. Which of the following is most likely the result of this mutation?
a) a msisense mutation
b) missplicing of the intron
c) a nonsense mutation
d) a silent mutation
e) misregulation of the gene
e) misregulation of the gene
One form of regulation used by intestional cells to slow iron entry when the body iron is sufficient is to
a) increase degradation of transferrin receptor mRNA through binding of the iron response element protein (IREBP) to the 5’ untranslated region (5’UTR).
b) inhibit translation through binding of the iron response element binding protein (RIEBP) to the 5’ untranslated region (5’ UTR) of the apoferritin mRNA
c) cleave the iron response element binding protein (IREBP) due to proteases in the cis GLogi, freeing it to act as a transcription factor that binds to the pormoter region of the transferrin receptor gene.
d) increase degradation of transferrin receptor gene through binding of the iron response element binding protein (IREBP) to the 5’ untranslated region (5’UTR)
e) inhibit translation through binding of the iron response element binding protein (IREBP) to the 5’ untranslated region (5’UTR) of the apoferritin gene
…?
The test key says B, but I have doubts
